Objective To evaluate the application of quantitative sensory testing (QST) to diabetic peripheral neuropathy. Methods TSA 2001 thermal sensory analyzer and VSA 6003 vibratory sensory analyzer made in Israel were used for thermal, vibratory tests and sensory conduction velocity (SCV) at four different locations of extremities in 45 diabetics and 22 normal persons. Results The thermal threshold (TT) and vibratory threshold (VT) of the diabetics were higher than those of age matched normal controls. In diabetics the TT was more frequently abnormal than the VT, which suggested that the small nerve fibers were more vulnerable than large fibers. Quantitative thermal testing (QTT) was more sensitive than quantitative vibratory testing (QVT) and SCV in diabetic peripheral neuropathy, especially in subclinical neuropathy. There was no significant correlation between the TT or VT and blood glucose in diabetics. Conclusion QTT is a sensitive method for diagnosis of diabetic neuropathy.

Objective 　To evaluate the quantitative sensory testing in Guillain-Barre syndrome (GBS) and polyneuropathy (PNP). Methods　The quantitative sensory test (QST) was performed with Thermal Sensory Analyzer(TSA-2001) and Vibratory Sensory Analyzer(VSA-6003). Thermal and vibratory sensory tests were performed in the left patients with GBS or PNP and healthy subjects, on four sites of the left limbs by the method of Limits. Stimultaneously sensory conduction velocity (SCV) was measured. Results　There were increased TT and VT on distal limbs in the patients with GBS (with or without the symptoms or signs of disturbance of sensation) and PNP. QST in GBS and PNP was more sensitive than the clinical examination and SCV. There was significant association between VT and SCV in GBS, but not a significant association between TT\, VT and SCV in PNP. There was a paradoxical heat sensation in two patients with uremic PNP. Conclusions　QST is a sensitive and reliable test and can be a useful test in the diagnosis of PNP.

Adenoid cystic carcinoma(ACC) of the salivary gland constitutes approximately 21.9%-24.0% of all salivary gland malignant tumors,and is described as a tumor with indolent,but persistent and recurrent,growth and late onset of metastases,leading eventually to death.This review focuses on the advances in the studies of the diagnosis,treatment,and prognosis of ACC in the recent years.

OBJECTIVETo investigate the effects of closed reduction and ulna intramedullary nail fixation for the treatment of fresh Monteggia fractures of Bado type I and II in children.

METHODSTwenty-three children patients with Monteggia fracture during July 2010 to September 2013 were treated by closed reduction and ulna intramedullary nail fixaion including 18 boys and 5 girls with an average age of 9.3 years old ranging from 6 to 13 years old. Among them,15 cases were Bado type I and 8 cases were Bado type II. There were 9 cases with radial nerve injury. The operation time,the recovery of nerve injury, the fracture healing and the function of elbow were observed and recorded.

RESULTSAll patients were followed up for 6 to 24 months (12 months on average). All patients were obtained bone healing. According to Anderson standard, at the final follow-up, 20 cases got excellent result, 2 cases got good result, and one case got fair result.

CONCLUSIONTreatment of the fresh Monteggia fractures in children by closed reduction and ulna intramedullary nail fixation has advantages of simple operation, less trauma and good results.

Adolescent ; Child ; Female ; Fracture Fixation, Intramedullary ; methods ; Fracture Healing ; Humans ; Male ; Monteggia's Fracture ; surgery ; Ulna ; surgery

Objective To report the clinical result of island flaps of hand in reparing of hand skin defects Methods According to location of skin defect, thirty eight cases with skin defect in hand were repaired by different types of island flap on hand Results The repair effect was satisfactory, almost all flaps were transplanted successfully, except two flaps The postoperative follow up period was 6 to 18 months, the blood supply, elasticity and texture of flaps were fine Conclusion Transfering of different types of island flap of hand is an easy, safe and reliable method with fewer complication

Objective For analyzing the outcome of toe transplantation Methods From 1992 to 2001, 24 cases of defect of fingers were treated with toe transplantation, including second toe transplantation for thumb in 19 cases, for index finger in 1 case, and for middle finger 2 cases, as well as second toe and third toe transplantation for middle and ring fingers in 2 cases Results The transplantated toe survived in 23 cases The reconstituted fingers and thumbs showed good shape and excellent function Conclusion Careful examination, reasonable design of reconstrction plan, and fine manipulation to protect blood vessels from trauma induced by operation play a key role in the toe transplantation, especially in the presence of abnormal blood vessels

Purpose:To detect DNA polymerase ? gene (pol?) mutations in human gastric cancer specimens and the relationship between H.pylori infection and pol? mutation. Methods:Extracting total RNA from gastric carcinoma,corresponding cancer specimens tissues and normal tissues, synthesizing cDNA and then using them as templates proceed PCR,The products of PCR were checked by SSCP. Extracting DNA from the specimen, we could detect the H.Pylori from the tissue of gastric carcinoma and the tissue adjacent to them by PCR.Results:There were 7 abnormal SSCP of 32 gastric carcinoma samples, and the mutation rate was 21.9%, but nothing abnormal was found in the tissues adjacent to the tumor. The results of H.Pylori DNA were positive in 15 samples from 32 gastric carcinoma tissues. Positive rate was 46.9(15/32).Detection result of tissues adjacent to tumor was consistent with gastric carcinoma. Comparing pol? SSCP to H.pylori-DNA in gastric carcinoma,we found the positive samples of pol? SSCP correlated with H.pylori-DNA.Conclusions:It is suggested that the pol?gene mutation may be associated with carcinogenesis and development of human gastric cancer. H.pylori infection is possibly related to pol? mutation in gastric carcinoma.

Bile Duct Neoplasms ; etiology ; pathology ; Bile Ducts, Intrahepatic ; pathology ; Carcinoma in Situ ; etiology ; pathology ; Carcinoma, Papillary ; pathology ; Cholangitis, Sclerosing ; complications ; Diagnosis, Differential ; Humans ; Precancerous Conditions ; etiology ; pathology

Adenomatous Polyposis Coli ; genetics ; pathology ; Colonic Neoplasms ; classification ; genetics ; pathology ; Colorectal Neoplasms, Hereditary Nonpolyposis ; diagnosis ; genetics ; DNA Glycosylases ; metabolism ; Humans ; Intestinal Polyps ; pathology ; Lymphatic Metastasis ; Neoplasm Staging ; Neuroendocrine Tumors ; classification ; pathology ; Precancerous Conditions ; pathology ; Rectal Neoplasms ; classification ; genetics ; pathology ; World Health Organization

CA-19-9 Antigen ; metabolism ; Carcinoembryonic Antigen ; metabolism ; Carcinoma ; pathology ; Carcinoma in Situ ; etiology ; genetics ; metabolism ; pathology ; Chromosomes, Human, Pair 17 ; Chromosomes, Human, Pair 5 ; Diagnosis, Differential ; Gallbladder Diseases ; pathology ; Gallbladder Neoplasms ; etiology ; genetics ; metabolism ; pathology ; Humans ; Loss of Heterozygosity ; Microsatellite Instability ; Polyps ; pathology ; Precancerous Conditions ; etiology ; genetics ; metabolism ; pathology