In thirteen adult male patient with scaphoid nonunion associated with DISI(Dorsal intercalated Segment Instability) defined as scapholunate angle is greater than 70 degrees of the radiolunate angle is greater than 10 degrees, anterior interpostitional bone grafting has been performed. Surgical procedure: 1) Closed reduction of lunate(reduction of DISI) by volar flexing of the wrist and holding the position by Kirschner wire inserted obliquely through the radial styloid to lunate. 2) Radical curettage of nonunion site and intraoperative measurement of the gap in the scaphoid through volar approach. 3) A bicortical wedge shaped graft from the iliac crest was then impacted between the fragments. 4) Temporary K-wire fixation of the grafted scaphoid from the scaphoid tubercle to prevent distortion of nonunion site and loss of fixation. 5) A Herbert screw was then inserted. Results: Mean patient age was 24.5 years, and mean duration of nonunion before surgery was 19.4 months. Mean follow-up time was 22.6 months. The nonunion involved the middle one-third of scaphoid in 11 patients and distal one-third in 2 patients. The mean postoperative grip strength was 39.4kg by Dynamometer(PC-5303J). The mean postoperative range of motion was volar flexion 50.5 degrees; dorsiflexion 47.3 degrees. The scaphlunate angle decreased from a mean of 78.8 preoperatively to 52.9 degrees postoperatively. The radiolunate angle was decresed from a mean of 16.8 degrees prope- ratively to a mean of 1.8 degrees postoperatively. Union was obtained in all 13 cases, According to Herbert and Fisher's formulation, 2 excellent, 10 good and 1 fair results were obtained from our study. The results of the series suggest that treatment of scaphoid nonunion associated with DISI by this method is an effective method that reconstitutes scaphoid anatomy and promotes excellent wrist function.
Adult ; Bone Transplantation ; Curettage ; Follow-Up Studies ; Hand Strength ; Humans ; Male ; Methods ; Range of Motion, Articular ; Transplants ; Wrist

BACKGROUND: IgA nephropathy is characterized by showing a prominent mesangial deposition of IgA in biopsy specimens. More than 20% of these patients progress to an end-stage renal disease over a period of 20 years. However, it is difficult to perform renal biopsies in all patients who present with hematuria or proteinuria. The present study was undertaken to determine whether discriminant analysis before renal biopsy is useful in the diagnosis of IgA nephropathy. METHODS: A total of 144 patients who were diagnosed by renal biopsy were analyzed. This group of 144 patients included 76 patients who had an IgA nephropathy, and did not include those patients that had systemic lupus erythematosus, Henoch-Schonlein purpura or other systemic diseases, and 68 patients with a different kind of primary chronic glomerulonephritis. Discriminant analysis was used to clearly demarcate these two groups by using 20 clinical variables. RESULTS: Among the 20 clinical variables, the levels of serum albumin, serum IgG, serum IgA, the degree and quantitation of proteinuria, the degree of microhematuria, and the RBC counts of the urinary sediments in the IgA nephropathy group were significantly higher than those in the non-IgA nephropathy group. Also, the presence of subjective symptoms was significantly different between the two groups. Using the stepwise method, serum albumin (ALB), serum IgA (IGA), and the degree of microhematuria (MICRO) were chosen to be the discriminant markers and resulted in a correct classification rate of 81.3%. The discriminant function (D) was 'D=0.842XALB+0.523XIGA+0.414XMICRO'. CONCLUSIONS: It was considered that discriminant analysis using clinical markers such as serum albumin, serum IgA, and degree of microhematuria before renal biopsy is useful in the clinical diagnosis of IgA nephropathy.
Biomarkers ; Biopsy ; Classification ; Diagnosis* ; Discriminant Analysis ; Glomerulonephritis ; Glomerulonephritis, IGA* ; Hematuria ; Humans ; Immunoglobulin A* ; Immunoglobulin G ; Kidney Failure, Chronic ; Lupus Erythematosus, Systemic ; Proteinuria ; Purpura, Schoenlein-Henoch ; Serum Albumin

BACKGROUND: Recently, sufficient numbers of lymphocytes that may cause alloimmunization have been detected in fresh frozen plasma (FFP) and the need for filtration and/or irradiation of FFP for certain patients has been proposed. We examined the numbers of white blood cells (WBCs) in FFP and evaluated a new WBC-reduction filter designed for FFP. METHODS: A total of 118 units of FFP were analyzed. We counted WBCs by using the crystal violet-staining method. Forty-four units of FFP were tested for WBC numbers before and after filtration by using the Nageotte chamber. The viable WBC count was performed using the 0.4% trypan blue-staining method. The biologic activity of the coagulation factor viii was measured in 34 units of FFP before and after filtration with the ACL 3000 (Instrumentation Laboratory, Milano, Italy). RESULTS: In the 118 units of FFP, 39 units (33.1%) and 1 unit (0.9%) had counts greater than 1X10(6)/unit and 5X10(6)/unit, respectively. The filter reduced the WBC numbers to less than 1X106/unit in all units. The average percentage of viable WBCs before and after filtration was 34.9% and 4.7%, respectively. The average leukocyte removal rate of the WBC-reduction filter was 81.0%. The average factor viii activity before and after filtration was 72.2 U/dL and 75.1 U/dL, respectively. CONCLUSIONS: Some FFP prepared by the Korean Red Cross blood center may contain enough to require WBC-reduction filtration. Therefore, WBC-reduction filtration of FFP should be considered in order to prevent adverse effects, particularly in those patients expected to receive repeated transfusions.
Factor VIII ; Filtration ; Humans ; Leukocytes* ; Lymphocytes ; Plasma* ; Red Cross

The aim of investigation is to calculate the mean value of the acetabular anteversion of normal Korean adult after closure of growth according to different gender and sex age group, to find out any significant difference of the value of acetabular anteversion to some other variables such as age, height, weight and radiographic inclination(abduction angle) of acetabulum. Transverse pelvic computed tomography(CT) scans of 360 right hips with no known pathology were examined. The study population consisted of 12 groups by gender (male and female) and age(from third to eighth decade). The number of each group was thirty. The scanning slice nearest the middle region of the acetabulum (nearest through the center of the femoral head) on the scout film was chosen. A measuring point was assigned at the anterior edge of the acetabulum and second at the posterior edge. The line connecting these points was drawn. The angle formed by this line and the plane sagittal to the pelvis was determined as acetabular anteversion. The data analysis was run on a statistical analysis system(SAS). The mean value of acetabular anteversion 19.8±5.4 degrees(17.1±5.6 in males, 22.2±5.4 in females), it was greater significantly in females than in males (p=0.0001). The mean value of acetabular anteversion in third decade male group than the third, fourth and fifth decade group significantly(p < 0.05). The mean value of acetabular anteversion of Koreans was similar to Caucasians value. The value of acetabular anteversion was relatively releated to age. In conclusion, the acetabular anteversion of Korean females was larger than the Korean males. It was increased with aging. When we perform the total hip arthroplasty and pelvic osteotomy or reorientation procedure, we must consider the acetabular anteversion by different gender and age group.
Acetabulum ; Adult ; Aging ; Arthroplasty, Replacement, Hip ; Female ; Hip ; Humans ; Male ; Osteotomy ; Pathology ; Pelvis ; Statistics as Topic

We developed Extor pins for Extor external fixator, it made of stainless steel and applied it clinically to manage open fractures and chronic osteomyelitis from December, 1993 to January, 1995. The main aim of present study is to compare the mechanical strength and biocompatibillity between Extor pins and AO Schanz pins, and to determine the safety and possibility of clinical use. We performed the biomechanical test for bending, tension, and shearing of pin itself using universal testing machine (LR5OK) and pullout test in cadeveric cortical femur to determine the bone holding power. There was no significant difference between Extor and AO Schanz pin (p>0.05). Clinically, the incidence of pin site infection, pin lossening, radiological rarefaction, and pathological change were not different significantly (p>0.05). Although Extor pins are somewhat different from AO Shanz pins in material and design characteristics, we can find the safety and possibility of clinical use of Extor pins made in Korea.
External Fixators* ; Femur ; Fractures, Open ; Incidence ; Korea ; Osteomyelitis ; Stainless Steel

BACKGROUND: Pelvic inflammatory disease (PID) is a microbial infection caused by the upward spread of infectious organisms through the cervical os. Early diagnosis and treatment of PID are essential for the prevention of sequelae such as ectopic pregnancies, infertility, and chronic pelvic pain. Although Chlamydia trachomatis and Neisseria gonorrhoeae are well-known causal agents of PID, there have been reports on some changes in PID-associated infection. The aim of this study was to investigate the infection patterns in patients with PID in Jeju. METHODS: Endocervical samples obtained from 65 patients with PID were tested for C. trachomatis, Mycoplasma genitalium, Mycoplasma hominis, N. gonorrhoeae, Trichomonas vaginalis, and Ureaplasma urealyticum using multiplex PCR. RESULTS: The samples were positive for C. trachomatis (63%), M. hominis (34%), U. urealyticum (20%), M. genitalium (17%), N. gonorrhoeae (9%), and T. vaginalis (6%). CONCLUSIONS: This study showed that C. trachomatis infection was prevalent and the incidence of M. hominis was higher than that of U. urealyticum.
Chlamydia trachomatis ; Early Diagnosis ; Female ; Humans ; Incidence ; Infertility ; Mycoplasma genitalium ; Mycoplasma hominis ; Neisseria gonorrhoeae ; Pelvic Inflammatory Disease ; Pelvic Pain ; Polymerase Chain Reaction ; Pregnancy ; Pregnancy, Ectopic ; Trichomonas vaginalis ; Ureaplasma urealyticum

No Abstract Available.
Posterior Cruciate Ligament*

It has been reported that cavernous hemangiomas in the spine are generally located in vertebral bodies. Wereport a case of epidural cavernous hemangioma, a very rare condition, at the C7-T2 level. MR images showed adumbbell-shaped mass, with iso and high signal intensity on T1- and T2-weighted images, respectively. The mass wasintensely enhanced following Gd-DTPA injection.
Gadolinium DTPA ; Hemangioma, Cavernous* ; Spine

BACKGROUND: Mycoplasma pneumoniae (MP) is a major cause of community-acquired pneumonia in children. The particle agglutination (PA) assay is a clinical test routinely used to detect MP infection and to determine total MP antibody titers. Using this assay, however, it is difficult to differentiate between IgM and IgG antibodies. The aim of this study was to investigate the seroprevalence of MP IgM antibodies in children living in Jeju Island. METHODS: We investigated the seroprevalence of mycoplasma IgM antibodies in 1,693 patients in the age of 0-10 yr who were ordered for mycoplasma IgM antibody testing in Cheju Halla Hospital between April 2011 and March 2013. Results were classified according to age, sex and the month and year during which the samples were obtained. RESULTS: The overall positive rate for mycoplasma IgM antibody was 24.7% and was higher in females than in males (P=0.012). The positive rate was lowest in infants under 6 months of age, and gradually rose with increasing age until the age of 4 yr. A major increase in positive rates was observed between January-April of 2012 and minor cyclical increases were also observed at 2-4 month intervals during the study period. CONCLUSIONS: The seroprevalence of mycoplasma IgM antibodies rises gradually with age until the age of 4 yr. A major peak in MP IgM antibody-positive cases was observed in early 2012, with minor cyclical increases at every 2-4 months. These results will be helpful in the interpretation and diagnosis of MP in children living in Jeju Island.
Agglutination ; Antibodies* ; Child* ; Diagnosis ; Female ; Humans ; Immunoglobulin G ; Immunoglobulin M* ; Infant ; Jeju-do ; Korea ; Male ; Mycoplasma ; Mycoplasma pneumoniae* ; Pneumonia ; Pneumonia, Mycoplasma* ; Seroepidemiologic Studies*

BACKGROUND: Mycoplasma pneumoniae (MP) is a major cause of community-acquired pneumonia in children. Currently, no study exists regarding the frequency of the mycoplasmal antibody on Jeju Island. The aim of the present study was to investigate the frequency of mycoplasmal antibody among children living on Jeju Island. METHODS: From March 2009 to February 2011, the frequency of mycoplasmal antibody among 1580 pediatric (<10 years old) patients who were tested for the mycoplasmal antibody titer in Cheju Halla Hospital were retrospectively investigated. The authors also analyzed the positive rates according to age, sex, and season. RESULTS: The frequency of mycoplasmal antibody titers were 69.4% for an antibody titer >1:40, 20.8% in an antibody titer >1:320, and 10.7% in an antibody titer >1:640. The positive rates of each antibody titer were lowest in children under the age of 6 months, and the positive rates increased gradually with age until 4 years, where the frequency showed a "plateau." There were minor cyclic increases of positive rate (>1:320, >1:640) every three months from August 2009 to June 2010, and there was a major increase of positive rate (>1:320, >1:640) from July 2010 to January 2011. However, there was no positive rate cyclic pattern of mycoplasmal antibody in the lower titer (>1:40) patients. CONCLUSION: The frequency of mycoplasmal antibody titer is lowest under the age of 6 months. The positive rates rise gradually with age until the age of 4 years. The present study showed minor peaks of mycoplasmal antibody titer every three months and a major peak of mycoplasmal antibody titer. The results can be helpful for the interpretation and diagnosis of MP among pediatric patients on Jeju Island.
Antibodies ; Child ; Humans ; Mycoplasma ; Mycoplasma pneumoniae ; Pneumonia ; Pneumonia, Mycoplasma ; Retrospective Studies