Adult ; Fibrous Dysplasia, Polyostotic ; complications ; Follow-Up Studies ; Humans ; Male ; Pituitary Neoplasms ; complications

Objective To discuss the distribution of TCM syndromes and clinical characteristics in adult viral pneumonia. Methods Retrospective analysis was carried out during 2009-2012 in 107 cases of adult viral pneumonia with virus antigen and serum virus IgM antibody positive detected with PCR, ELISA and IF method. The clinical symptoms, serology and TCM syndrome type distribution were analyzed. Results The average age of the patients with adult viral pneumonia was 34.78±11.4. The clinical symptoms were mainly fever, cough and sore throat, and defense phase symptoms such as headache and general aching were outstanding. TCM syndromes distribution accounted for 92.52%(99/107) of syndrome of wind-heat invading lung, syndrome of phlegm-heat congesting lung, syndrome of wind-heat with dampness, and syndrome of wind-cold to heat. Syndrome of wind-heat invading lung was commonly seen in disease course ≤7 d, and syndrome of phlegm-heat congesting lung in course >7 d. The viruses were mainly influenza A and B, parainfluenza virus. Among the 107 cases, 86 cases (80.37%) were infected with single virus. There were no significant difference among different pathogens in the distribution of type (P>0.05). Conclusion TCM syndrome distribution of adult viral pneumonia has some characteristics, and has correlation with disease course.

TORCH infection during pregnancy is a group of infectious diseases resulting from viruses and other microorganisms. According to the past over 20-year experiences in serum screening in China, several infections which should be performed in the first trimester, or even much earlier in pregnant period, are hepatitis B, syphilis, HIV, and these three infections are confirmed to be harmful to the fetus or infants and also diagnostic methods and treatment are available. Screening for rubella should be better performed before conception and no specific management is required with IgM+, while immunization is recommended before pregnancy with IgM-. Screenings for cytomegalovirus, toxoplasmosis and herpes virus are not recommended. Scnography is warranted if fetal abnormalities were resulted from the above infections and amniocentesis or cordocentesis might be required for further investigations.

Ischemia-reperfusion injury can cause graft injury, and rapamycin, as an immunosuppressant commonly used clinically, show multiple effects on graft which after reperfusion. Here, we will review the role of rapamycin in renal ischemia-reperfusion injury.

Objective To design and manufacture the simple lower fixtures of WXX2000 field medical box group, the medical boxes ZT-4-1 as an example. The principle, instrument, process and the applying of the device were introduced. Methods Based on the guidance principle of the ZT-4-1 medical box, the size of lower space and ampoule of the ZT-4-1 medical box were measured and design its layout, and then suitable instruments and materials of the device was selected, and external fixed wooden box and foam stuffing were produced step by step. Results The simple lower fixture is available for fixed and transportation safety. Conclusion The simple device is effective for fixed effect and can be used extensively.

ObjectiveTo evaluate the efficacy and tolerance of tolterodine in treating detrusor hyperreflexia in patients with spinal cord injury.Methods50 patients of spinal cord injury patients with detrusor hyperreflexia were involved in this study.The data from voiding diary were evaluated 7 days before and after the patients being treated with tolterodine 2 mg twice daily.ResultsAfter 12 weeks of treatment,the functional bladder volume increased from(114.0±44.3) ml to(207.7±54.9) ml,the mean frequency of micturition decreased from(8.9±2.7) /d to(4.6±2.5) /d,the mean volume of incontinence decreased from(646.7±348.9) ml to(426.6±291.3) ml,the mean frequency of incontinence decreased from(7.8±3.1) /d to(4.8±3.2) /d,which were all statistically different before and after treatment.5 patients felt dry mouth,but they could tolerated it.ConclusionTolterodine is an effective and well tolerable antimuscarinic agent for treating detrusor hyperreflexia after spinal cord injury.

Objective: To explore the clinical values of using flexible multi-analyte profiling (xMAP) technology for detection of high-risk human papillomavirus (HR-HPV). Methods: Six hundred and thirty eight cervical exfoliated cell samples were collected from women who lived in the region with high-incidence of cervical cancer in Shanxi province. The samples were tested with xMAP technology and Hybrid Capture 2 ® Assay (hc2). Pathological diagnosis was used as a hallmark to evaluate the detection results. HR-HPV infection rate and its genotyping distribution were analyzed and the coincidence of two methods above was assessed. Results: The sensitivity, specificity and accuracy of xMAP technology were 77.78%, 93.59% and 92.42%, respectively. The negative and positive predictive values were 98.13% and 49.30%, respectively. The prevalence rate of HR-HPV was 11.7%. HPV16 and 52 were the dominant types in non-neoplastic disease and cervical intraepithelial neoplasia (CIN) grade 1; HPV16 and 58 were the most common types in CIN2 samples; HPV16 was the most frequent type in CIN3 and cervical cancer. The lesion progress was positively related to the infection rate of HPV16, 52 or 58 (P<0.01). The Kappa value for agreement between xMAP technology and hc2 was 0.60. Conclusions: Compared with the hc2 test, the xMAP technology was highly specific, and the sensitivity is 77.78%. The agreement of these two methods is satisfactory. More improvements should be made to elevate the sensitivity of xMAP method and to increase the numbers of genotypes that can be detected.

Objective To investigate the clinical effects,complications and cautions for transcatheter supperselective internal maxillary artery and facial artery embolization for treatment of intractable epistaxis.Methods Eight patients with intractable epistaxis underwent transcatheter supperselective internal maxillary artery and facial artery embolization.Results Immediate hemostasis was obtained in all patients,while varying degrees of headache were observed,but no serious complications occurred.Conclusion Transcatheter supperselective internal maxillary artery and facial artery embolization is a safe,effective method for the treatment of intractable epistaxis.

Objective To compare the effects of laparoscopy and open operations on high ligation of internal spermatic veins for varicocele. Methods A retrospective study was conducted to look into the clinical data of 38 cases having undergone laparoscopic high ligation of internal spermatic veins and 46 cases having undergone open operations for high ligation. Results The two methods presented no significant differences in bleeding , operation time and hospital stay (P > 0.05);Both groups were fast in postoperative recovery, without any recurrence, atrophy of testis and hydrocele. Conclusions The endoscopic high ligation of internal spermatic veins is equal to open operations for varicocele.

Objective To evaluate the effects of Botulinum-A toxin (BTX-A) injection into detrusor to treat detrusor hyperreflexia and neurogenic incontinence in the patients with spinal cord injury (SCI). Methods A total of 31 patients with SCI(mean age,30 years;male 20,female 11) were included into the study.All the patients underwent urodynamic examination and voiding diary was recorded.300 U of BTX-A was dissolved in 15 ml of saline,and the solution of BTX-A was injected into 30 different points in detrusor using a flexible cystoscopic needle.The evaluation for the effects and follow-up included voiding diary,urodynamic testing and observation of adverse and toxic effects. Results After the first injection,29 of the 31 patients had symptom relief within 3 to 14 days;4 cases received the second injection;4 cases were treated in combination with anticholinergic medication;and 2 cases had no improvement and,therefore,received other treatments.The mean follow-up was 8.5 months. After 3-week treatment of BTX-A,the mean frequency of incontinence decreased from 14.2 to 2.5 times per day.The mean volume of intermittent catheterization (IC) increased from 124 to 495 ml each time.Urodynamic data showed that mean cystometric bladder storage volume increased from 133 to 475 ml,mean maximum storage detrusor pressure decreased from 62.7 to 17.1 cmH 2O(1 cmH 2O=0.098 kPa).No adverse and toxic effect was observed. Conclusions Our initial experience suggests that Botulinum-A toxin injection into detrusor to treat detrusor hyperreflexia and neurogenic incontinence in patients with SCI may be an effective,safe,feasible and micro-invasive treatment choice.However,it is necessary to observe its long term outcome.