1.The Influence of Hepatitis B Virus to Neonates.
Dong Hak SHIN ; Rac Kyun RO ; Sung Do YOON
Journal of the Korean Pediatric Society 1986;29(1):51-57
No abstract available.
Hepatitis B virus*
;
Hepatitis B*
;
Hepatitis*
;
Humans
;
Infant, Newborn*
2.A psychiatric study of patients with gastroscopy by means of BDI and STAI.
Sung Keun LEE ; Sook Haeng JOE ; Dong Kyun SHIN
Journal of Korean Neuropsychiatric Association 1991;30(6):1042-1062
No abstract available.
Gastroscopy*
;
Humans
3.A Clinical Study of Fractures and Dislocations of the Carpus
Jun Dong CHANG ; Sung Il SHIN ; Kyun Ho CHANG
The Journal of the Korean Orthopaedic Association 1989;24(5):1406-1418
In the fractures and dislocations of the carpus, prompt and accurate diagnosis is the prime prerequisite for restoring function to this most complicated joint in the body. And then, early precise reduction and continuous maintenance of the reduced position until ligamentous and bone healing is complete provide the best chance of achieving a satisfactory restoration of function. We analysed forty five cases of fractures and dislocations of the carpus which were treated for 5 years from Jan. 1984 to Dec. 1988 at the Department of Orthopedic Surgery, College of Medicine, Hallym University. The following results were obtained; l. Of the total 45 injuries, scaphoid fractures were seen in 32(71.1%), other carpal bone fractures except scaphoid in 13 patients(28.9%), and carpal bone dislocation and fracture- dislocations in 11 patients(24.4%). 2. Carpal scaphoid fracture 1) 19 of the 32 patients(59.4%) had an associated ipsilateral upper extremity injury. 2) This fracture was common in the young male. 3) A union rate(95.6%) was achieved using a usual conservative treatment for undisplaced racture(14), operative treatment for displaced(18). 4) The mean time to radiological union for all fractures was 11.1 weeks. Old fracture by SotoHall classification took the longest time to union(18.2 weeks), subacute fracture 13 weeks, and acute fracture 9 weeks. 5) 10 cases were treated for nonunion, 5 of 10 nonunions were classified as type (50%). 2 cases showed ultimately nonunion in spite of various sorts of treatment, which belonged to waist fracture. 3. Other carpal bone fractures except scaphoid were seen in 13(15 bones) of 45 injuries, and pisiform(4) and triquetrum(4) fractures were common. 4. Carpal dislocation and fracture-dislocations were seen in 11 of the 45 injuries and dorsal transscaphoid perilunate dislocations(4) were common. These were treated by C.R. and cast immobilization or O.R. and K-wire fixation relatively good results were obtained.
Carpal Bones
;
Classification
;
Clinical Study
;
Diagnosis
;
Dislocations
;
Humans
;
Immobilization
;
Joints
;
Ligaments
;
Male
;
Orthopedics
;
Upper Extremity
4.Histochemical studies on Echinorhynchus gadi (Acanthocephala).
Jung Kyun CHU ; Shin Yong KANG ; Jong Phil CHU ; Dong Wook SUNG
The Korean Journal of Parasitology 1977;15(1):36-42
The distribution of glycogen, polysaccharide, mucopolysaccharide, lipid and nucleic acid has been studied in Echinorhynchus gadi(Acanthocephala). The results were summarized as follows: Glycogen and polysaccharide was demonstrated by Bauer PAS reaction technique and was found in fertilization membrane in ovum, central nuclear mass in acanthor and lemnisci, hypodermis in cystacanth. Mucopolysaccharide was demonstrated by Mowry alcian blue staining technique and was found in outer membrane, fibrillar coat, fertilization membrane and inner membrane in acanthocephalan ova. Lipid was demonstrated by Smith Nile blue stain and Lison Sudan black B staining technique and was found roughly parallel to that of polysaccharide. Nucleic acid was demonstrated by Rosenbeck Feulgen reaction, Taft methylgreen-pyronin stain and Diengdoh acridine orange staining technique and found in central nuclear mass in acanthor, also, was found in lemnisci, proboscis and hypodermis in cystacanth.
parasitology-Acanthocephala
;
histochemistry
;
Echinorhynchus gadi
;
glycogen
;
mucopolysaccharide
;
lipid
;
nucleic acid
5.Measurement of digital blood flow using impedance plethysmography.
Dong Kyun RAH ; Kuek Shun SHIN ; Jae Duk LEW ; Deok Won KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(4):602-608
No abstract available.
Electric Impedance*
;
Plethysmography, Impedance*
6.Immunohistochemical study of p21 and p53 expression in ameloblastoma.
Dong Joon SHIN ; Hoon MYOUNG ; Kyeng Kyun HWANG ; Myung Jin KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2003;29(4):199-205
The p53 protein was discovered in 1979 as cellular 53-kD nuclear phosphoprotein bound to the large transforming antigen of SV40 virus. P21WAF1/CIP1, which has been described as the critical downstream mediator of p53, is known to suppress DNA replication and arrest the G1 cell cycle by quaternary complex with cyclin D, cyclin-dependent kinase(CDK) and proliferating cell nuclear antigen(PCNA). In these days, some studies shows that the p21 can be induced by independent pathways. There are various reports about the expression of p21 (67%.82.4%) in oral squamous cell carcinoma. But these studies are mostly done in malignant tumor not in benign tumor. So we decided to study the expression of p21 in ameloblastoma and the relationship between p53 and p21 as a downstream mediator of p53 in ameloblastoma. We investigated the expression of p21 and p53 with the method of immunohistochemistry. We selected 30 cases of ameloblastoma tissue blocks (acanthomatous type: 5 cases, follicular type: 8 cases, plexiform type: 17 cases) imbedded in paraffin. We used 30 cases of normal gingival tissues and 30 cases of squamous cell carcinoma tissues (SCC) respectively and compared their results with those of ameloblastoma. We made slides with the streptavidin-biotin methods and used monoclonal antibody DO-7 (Novocastra, Newcastle, United Kingdom) as p53 antibody and monoclonal antibody M7202 (DAKO, California, U.S.A.) as p21 antibody. We used Pearson's correlation coefficient to analyse the relationship. The results were as follows: 1. p21 was expressed in ameloblastoma about 30% and this is lower than that of normal gingiva and SCC. 2. In normal gingiva and ameloblastoma, p21 expression was correlated with p53 expression. 3. In SCC, p21 were expressed about 83.3% and this is more than that of p53. But there was no correlation between p21 and p53 expression. We confirmed p21 expression and relation with p53 in ameloblastoma. But, to confirm the function of p21, more studies about p21 expression in malignant ameloblastoma and ameloblastic carcinoma are needed.
Ameloblastoma*
;
Ameloblasts
;
California
;
Carcinoma, Squamous Cell
;
Cell Cycle
;
Cyclin D
;
DNA Replication
;
Gingiva
;
Immunohistochemistry
;
Paraffin
;
Simian virus 40
7.Two Cases of Cavernous Hemangioma of the Palpebral Conjuntiva.
Ho Kyun SONG ; Sung Kee CHO ; Dong Eul SHIN
Journal of the Korean Ophthalmological Society 1987;28(5):1169-1173
Hemangioma appearing on the conjuntiva is a rare benign tumor which may be derived from vessels of conjuntiva, sclera, ocular muscles and orbit. Recently, we have experienced two cases of well encapsulated movable, round and slightly nodular conjuntival masses which had smooth, dark bluish-red colored surfaces. The masses were simply excised and histopathologic study revealed cavernous hemangioma.
Hemangioma
;
Hemangioma, Cavernous*
;
Muscles
;
Orbit
;
Sclera
8.Three Cases of Waardenburg's Syndrome in One Family.
Journal of the Korean Ophthalmological Society 1987;28(5):1137-1142
Warrdenburg's syndrome, a rare hereditary disease, may be transmitted as an irregular autosomal dominant traits, which is distinguished by lateral displacement of the medial canthi and inferior lacrimal puncta, broad and prominant nasal root, hyperplasia of the medial portions of the eye-brows, white or grey colored forelock, partial or total heterochromia of the irides, congenital deafness, etc. Recently, the authors have experienced three cases of Waardenburg's syndrome in one family. They were 29 year old male, his 4 year old son and 3 year old daughter. We report these interesting cases with a brief review of literatures.
Adult
;
Child, Preschool
;
Deafness
;
Genetic Diseases, Inborn
;
Humans
;
Hyperplasia
;
Male
;
Nuclear Family
;
Waardenburg Syndrome*
9.Clinical analysis of composite graft replacement of amputated digital tips.
Hea Kyeong SHIN ; Jong Mun LEE ; Dong Sug JUNG ; Won Kyun JUNG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2000;27(1):40-45
Composite grafting remains a technique which is used reluctantly and without great hope of success. In the recent two years, unexpectedly good result of composite graft was gained from 30 cases. The purpose of our study is to identify factors influencing success and to overlook long-term problems from a cosmetic and a functional view point. A retrospective review and a questionnaire about 30 fingers of 29 patients which were operated for composite graft at Kyongju hospital of Dongguk university from March 1997 to February 1999 were carried out. In all cases of composite grafting, tie-over dressing and heat lamp were applied and left for five days. And following result and conclusion were obtained. 1. 24(80%) of 30 finger tips replaced as composite graft were survived completely or partially. 2. At children with an age range 1 to 14, the survival rate (100%) of composite grafted tips was higher than that (75%) at adults. So, patient's age was important factor for success. 3. The type of injury was more important factor than the level of amputation. The survival rate(100%) of tips to cutting injury was higher than that(75%) of tips to crushing injury. 4. The delay in time from amputation and replacement did not significantly correlate with the survival rate. But, all tips replaced within 3 hours were survived completely or partially. 5. Even if partial necrosis on grafted tips was present, a result of long-time conservative treatment with minimal debridrement was excellent. Especially in children, the tips with conservative treatment showed normal appearance, several months later. 6. Cosmetic and functional results were better in child group and in groups with higher survival rate. Most common problem in cosmetic aspect was a short digit and that in functional aspect was a tender tip. 7. As a heat lamp increased blood supply, we could obtain better outcome.
Adult
;
Amputation
;
Bandages
;
Child
;
Fingers
;
Gyeongsangbuk-do
;
Hope
;
Hot Temperature
;
Humans
;
Necrosis
;
Surveys and Questionnaires
;
Retrospective Studies
;
Survival Rate
;
Transplants*
10.Trend of Serum Lipid Levels in Normal Koreans.
Sung Wook HAN ; Dong Ho SHIN ; Sang Eun JOO ; Bang Hun LEE ; Chung Kyun LEE
Korean Circulation Journal 1983;13(1):107-112
The authors underwent the serum lipid study, involving the lipoprotein fraction, and the HDL-cholesterol mean values in normal Korean adults visited to Hanyang University Hospital, and also compared with the previously reported serum lipid studies. The results are as follows; 1) The mean values of triglyceride, total cholesterol, and phospholipid were 103.3+/-17.1mg%, 188.9+/-18.2mg%, and 196.7+/-19.8mg%, respectively. 2) Compared with the past 7 years triglyceride showed increasing tendency with significance, and cholesterol and phospholipid showed slightly increasing tendency. 3) In the serum lipoprotein fraction, the mean values of alpha-lipoprotein, pre-beta-lipoprotein, and beta-lipoprotein were 37.2+/-5.9%, 16.0+/-4.2%, and 48.6+/-5.2%, respectively. 4) Compared with the past 10 years, the alpha-, and pre-beta-lipoprotein showed increasing tendency, meanwhile, beta-lipoprotein revealed decreasing tendency. 5) The mean value of HDL-cholesterol was 52.3+/-14.6mg%, and the ratio of HDL-cholesterol to total cholesterol(HDL-cholesterol/total cholesterol) was 28.2+/-7.9. 6) Compared with the past 2 years, HDL-cholesterol level showed slightly increasing tendency.
Adult
;
Cholesterol
;
Humans
;
Lipoproteins
;
Triglycerides