1.Pityriasis Rotunda with Familial Occurrence.
Jong Kyu YANG ; Dong Won LEE ; Baik Kee CHO
Annals of Dermatology 1997;9(3):194-196
Pityriasis rotunda is an uncommon chronic dermatosis characterized by multiple, round or oval, hyperpigmented or hypopigmented patches that have a fine scale on the trunk and extremities. Most of the cases reported predominantly occurred in Oriental and black patients in association with internal disease. However, in Caucasians it has been documented in healthy persons usually as a familial tendency. We report a case of pityriasis rotunda which showed familial occurrence and had no underlying disease.
Extremities
;
Humans
;
Pityriasis*
;
Skin Diseases
2.Detection of the Proliferation of Muscle Fibers During Limb Lengthening by Monoclonal Antibody to Bromodeoxyuridine
Hui Wan PARK ; Kyu Hyun YANG ; Dong Min KANG
The Journal of the Korean Orthopaedic Association 1996;31(2):265-269
Soft tissue related complications are quite frequent in limb lengthening. Muscle fibers may proliferate or regenerate after stretching injury over 10-20% of their original length. However, the cells which are engaged in this phenomenon are not confirmed yet. We chased the S-phase cells (phase for DNA replication) in the posterior leg muscle during limb lengthening by immunohistochemical technique. We lengthened the tibiae of fifteen New Zealand white rabbits. We divided them into three groups and each group is consisted of five rabbits. In group 1, we lengthened the left tibiae by 10% of their original length, in Group 2, 20%, and in group, 3, 25%, respectively, At the end of lengthening posterior muscles of lengthened left side and of controlled right side were fixed and processed for Immunohistochemical staining which could detect the incorporation of bromodeoxyuridine(BDU). Labelling index(LI:% of positively stained S-phase nuclei) of group 1 was zero. LI of groups for more than 20% lengthening (sum of group 2 and 3) was statistically significant. In conclusion, nuclei around or within the muscle tissue are in S-phase during limb lengthening which means proliferation of the muscle fivers or of the certain cells that abut muscle fibers.
Bromodeoxyuridine
;
DNA
;
Extremities
;
Immunohistochemistry
;
Leg
;
Muscles
;
Rabbits
;
Tibia
3.A CLINICAL STUDY ON MIDFACIAL FRACTURE.
Tae Kyu KIM ; Yeong Cheol CHO ; Dong Kyu YANG ; In Kyo CHUNG ; Jong Ryoul KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1997;23(3):458-464
The midface are bounded by a line connecting the two zygomaticofrontal suture, passing through the frontomaxillary and frontonasal suture, and limited below by the occlusal plane of maxillary teeth. Midface fractures include fractures affecting the maxilla, the zygoma, and the nasoorbital ethmoid complex. Midface fractures can be classified as LeFort 1, II, III fractures, sygomaticomaxillary complex fractures, zygomatic arch frationctures, or nasoorbital ethmoid fractures. These injuries may be isolated or occur in combine. And sort tissue injuries to the facial structures are commonly encountered in the treatment of midface fractured patient. Soft tissue wounds may be limited to the superficial structures, but more serious injuries may extend to involve anatomic structures such as the sensory and motor nerves of the face; the parotid, or nasolacrimal glands or ducts ; or the dentoalveolar structures. Especially, these fractures are combined with the orbit, brain injuries and skull base fractures. This is to report the incidence, causes, criteria, complication and treatments of patients who visited our department for midface fracture, for last 10 years.
Brain Injuries
;
Dental Occlusion
;
Humans
;
Incidence
;
Maxilla
;
Orbit
;
Skull Base
;
Sutures
;
Tooth
;
Wounds and Injuries
;
Zygoma
;
Zygomatic Fractures
4.Complete remission of maxillary and infratemporal squamous cellcarcinoma after induction chemotherapy.
Jong Ryoul KIM ; One Ryong MOON ; Sang Jun PARK ; Uk Kyu KIM ; Dong Kyu YANG
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1992;18(1):91-97
No abstract available.
Induction Chemotherapy*
5.Change of Femoral Anteversion during Closed Femoral Intramedullary Nailing
Kyu Hyun YANG ; Dae Yong HAN ; Dong Eun SHIN ; Dong Min KANG
The Journal of the Korean Orthopaedic Association 1996;31(2):218-224
Average anteversion of the femur is 15.3 degree. Ultrasound, computerized tomogram, and three dimensional reconstruction from CT or MRI have been used for more accurate measurement of the anteversion. There are two methods in measuing anteversion angle from CT scan:one is by drawing a mid line through long axis of the femoral neck (conventional method). Another is by drawing a line from the center of the head to that of the neck at the base of the trochanter using several cut slices (Murphy’s method). We compared these methods with fluoroscopic measurement of the Anteversion. We traced the change of the anteversion before and after closed femoral intramedullary (IMO) nailing to evaluate the origin of malrotation of the femur. 1. Normal anteversion angles were measured in 15 cases. Average anteversion angle was 6.9 degrees by conventional method, 12.3 degrees by Murphy’s method, and 12.2 degrees by fluoroscope. 2. Anteversion angles were measured after IM nailing in 18 cases. Average was 17 degrees by Murphy’s method and 15.2 degrees by fluoroscope. Mean of difference between these two methods sea 6.3 degrees. That was 1.7 degrees in normal side. 3. Change of the anteversion angle between before and after IM nailing was measured in 17 cases by fluoroscope. Average anteversion angle before the operation was 11.9 degrees and it was change to 15.8 degrees after operation. Mean of these change was 7.1 degrees. 4. Pereperative traction provides important information on change of anteversion. Reduction excessive flexion of proximal fragment was a origin of change of anteversion during nailing procedure. Conclusion : Malrotation of the femur after IM nailing must be keep in mind and it may be preventable by fluoroscopic control of the rotation in nailing procedure.
Femur
;
Femur Neck
;
Fracture Fixation, Intramedullary
;
Head
;
Magnetic Resonance Imaging
;
Methods
;
Neck
;
Traction
;
Ultrasonography
6.Influence of left ventricular function on the pattern of left ventricular diastolic filling assessed by doppler echocardiography in dilated cardiomyopathy.
Dong Hun KIM ; Seong Wook HONG ; Kyeong A OH ; Jin Weon JEONG ; Yang Kyu PARK ; Ock Kyu PARK
Korean Circulation Journal 1993;23(2):262-272
BACKGROUND: Recently, Doppler echocardiography has been widely used to evaluate left ventricular(LV) diastolic filling. However, There are only limited date about the influence of LV systolic function on the pattern of left ventricular diastolic filling. METHODS: To evaluate the changes of Doppler echocardiographic parameters of left ventricular filling induced by variations in left ventricular systolic function in dilated cardiomyopathy(DC) with heart failure(HF), 25 patients(M : F=14 : 11) with DC and HF, and 21 age-matched normal subjects(M : F=13 : 8) were examined by ECG, phonocardiography and echocardiography. From the Doppler recording, A2D(time from second heart sound to the onset of early diastolic mitral flow), peak velocity at early diastole(E) and late diastole(A), ratio of E to A velocity(E/A) and flow velocity integral(FVI) were measured. RESULTS: In 22 patients with DC and HF without mitral regurgitation(MR), A2D was significantly prolonged(119.5+/-12.7 vs 92.4+/-14.1msec, p<0.01), and early diastolic peak velocity and E/A velocity ratio were decreased as compared with the normal subjects(E=0.39+/-0.08 vs 0.57+/-0.12m/sec, p<0.01, E/A : 0.87+/-0.19 vs 1.33+/-0.19 vs 1.33+/-0.18, p<0.05). There were significant correlations between A2D and FVI(r=+0.73, p<0.01), and between E/A velocity ratio and FVI(r=-0.78, p<0.01). However, in 3 patients with MR, A2D(88.7+/-12.1msec), E(0.56+/-0.05m/sec), and E/A(1.32+/-0.12) were similar to those in normal subjects, despite of decreased FVI(12.0+/-0.9cm). CONCLUSIONS: These data show that a change of left ventricular systolic function in patients without MR may influence a diastolic filling pattern of left ventricle but not in patient with MR, and suggest that MR masks left ventricular distolic filling abnormalities.
Cardiomyopathy, Dilated*
;
Echocardiography
;
Echocardiography, Doppler*
;
Electrocardiography
;
Heart
;
Heart Sounds
;
Heart Ventricles
;
Humans
;
Masks
;
Phonocardiography
;
Ventricular Function, Left*
7.Cephalometric analysis of postsurgical behavior of mandibular prognathism
Jong Ryoul KIM ; Tae Kyu KIM ; In Kyo CHUNG ; Dong Kyu YANG ; Soo Byung PARK ; Woo Sung SON ; Byung Tae RHEE
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons 1993;15(2):123-128
No abstract available.
Prognathism
8.Truncus Arteriosus Associated with Interrupted Aortic Arch.
Chang Hyun YANG ; Jae Seung YANG ; Jun Hee SUL ; Dong Soo KIM ; Sung Kyu LEE ; Dong Shik CHIN
Journal of the Korean Pediatric Society 1988;31(6):779-783
No abstract available.
Aorta, Thoracic*
;
Truncus Arteriosus*
9.Serum Interleukin-6 Concentration in Carcinoma of the Cervix.
Yong Ju LEE ; Jae Wook KIM ; Ki Seok OH ; Oh Seung YANG ; Dong Kyu KIM
Korean Journal of Gynecologic Oncology and Colposcopy 1993;4(3):1-6
Interleukin-6(IL-6) is a multifunctional cytokine, and deregulated IL-6 gene expression has been implicated as being involved in the pathogenesis of a number of diseaaes. So we measured the serum level of IL-6 to find a relationahip between uterine cervical cancer and serum IL-6 level. The serum levels of IL-6 were meesured m 54 patients adrnitted to the Severance hospital, from August, 1992 to February, 1993, of whom 27 patients were diagnosed as invasive cancer of cervix, 17 as CIN, and also utilizing 10 patiente diagnosed as uterine myoma as a control group for matched age and parity. The average serum level of IL-6 in invasive cancer, CIN, and uterine myoma were respectively 30.33pg/ml, 37.27pg/ml, and 12.45pg Jml. In 22% af cervical cancer patients (6 of 27), and 27% of CIN patients (4 of 17) studied blood levels of II-6 were detected whereas only 10% of uterine myoma (1 of 10) shorved the same result. However, the difference does not seem to be statistically significant, There was no statistically significant difference among any of the groups, and age and stage did not show any significant cmrelation, and the results need furt,ber investigations.
Cervix Uteri*
;
Female
;
Gene Expression
;
Humans
;
Interleukin-6*
;
Leiomyoma
;
Parity
;
Uterine Cervical Neoplasms
10.Expression of Glutathione S-Transferase Isoenzymes in Carcinoma of the Uterine Cervix.
Jung Pil LEE ; Jae Wook KIM ; Oh Seung YANG ; Dong Kyu KIM
Korean Journal of Gynecologic Oncology and Colposcopy 1993;4(4):10-19
Glutathione S-Tanaferase (GST) is tripeptide, which plays a central role in the detoxification of electrophilic xenobioticas, including cytotoxic drugs and carcinogens, by conjugation with redueed glutathione. There are four major claases af human GST : pi, alpha, mu and rnicrosomal, They are propoaed as a marker for human and experimental neoplasia iincluding liver, kidney, lung,colon, uterine cervix, etc. Expression of pi, alphn, mu form of GST in control (15 cases), CIN (14 cases), invasive carcinoma (28 cases) of human uterine cervix was investigated immunohistochemically. They were selected fram September, 1992, to,June, 1992, in the department of Obstetrics and Gynecology, Yonsei university College of medicine. In nucleus, the expresaion of GST pi was increased statistically significant in case of CIN and invasive Ca. of Cx. compared to control(p=0.018, p=0.002). But expression of GST alpha, mu has no significant difference in each case. In cytoplasms, the expvession of GST pi was increased statistically significani, in case of CIN and invasive Ca. of Cx. (p=0.001, p<0.001). But expreasion of GST alpha, mu has no significant differenrce in each case. There was no statistically significant diHerence in expression of GST isoenzymes oC each nucleua and cytoplasm according to stage and cell type in Ca. oC Cx. The further evaluation of survival and expression of GST pi in Ca. of Cx. in order to establish new prognostic factor in Ca. of Cx.
Carcinogens
;
Cervix Uteri*
;
Cytoplasm
;
Female
;
Glutathione Transferase*
;
Glutathione*
;
Gynecology
;
Humans
;
Isoenzymes*
;
Kidney
;
Liver
;
Obstetrics