1.Placental Findings of Listeria Monocytogenes Infection in Twin Pregnancy: A Case Report.
Dong Hoon SHIN ; Dong Eun SONG ; Kyu Rae KIM
Korean Journal of Pathology 2007;41(2):119-122
A Listeria monocytogenes infection is relatively rare in healthy adults. However, the chance of an infection increases almost 17 times in pregnancy due to changes in the immune function. A Listeria monocytogenes infection results in characteristic gross and microscopic features in the placenta, including multiple yellowish nodules showing microscopic intervillous abscess and intervillositis. We describe the placental findings of a Listeria monocytogenes infection that was complicated by maternal sepsis, myocarditis and congestive heart failure. The infection was discovered in the 34th week of a twin gestation in a 28 year-old woman. This case should emphasize the importance of this condition to pathologists. Antibiotic treatment was started based on the placental histologic findings before a maternal blood culture confirmed growth of Listeria monocytogenes. Both the mother and twin babies were healthy at the time of this report.
Abscess
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Adult
;
Female
;
Heart Failure
;
Humans
;
Listeria monocytogenes*
;
Listeria*
;
Mothers
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Myocarditis
;
Placenta
;
Pregnancy
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Pregnancy, Twin*
;
Sepsis
3.Changes of c-Fos Protein Expression in Rat Brain Neurons after Formalin Induced Pain.
Kyu Geun HWANG ; Myeong Dong SHIN ; Ki Soo YOO
Journal of the Korean Child Neurology Society 1999;7(1):29-41
PURPOSE: The effects of pain on brain is not well known. Also, differences between somatic and visceral pains have not been fully elucidated. This study was conducted to investigate changes in the expression of c-Fos protein after somatic and visceral pains were induced by formalin. METHODS: Male rats(n=65) were underwent one of three procedures : (i) Control group, rats were left undisturbed in their cages; (ii) Somatic pain group, rats were injected subcutaneously with 0.1 ml of 10% formalin in the plantar surface of right hindpaw; (iii) Visceral pain group, rats were administered with same amount of formalin, as described above, in the rectum. Rats were sacrificed at increasing times(30 minutes, 1 hour, 2 hours, 6 hours, 1 day, 3 days and 7 days) after noxious formalin stimuli to hindpaws and rectums. Rat brains were removed and sliced in rat brain matrix. Brain slices were coronal sectioned at interaural 5.70-6.70mm. Serial sections were immunohistochemically reacted with polyclonal c-Fos antibody. The numbers of c-Fos protein immunoreactive neurons in cingulate cortex, primary somatosensory area, and hippocampus were examined and analyzed statistically with Mann-Whitney U test. RESULTS: 1) The numbers of c-For protein immunoreactive neurons in cingulate cortex, primary somatosensory area and hippocampus peaked at 2 hours after somatic pain stimuli and reached almost normal conditions at 7 days. 2) The numbers of c-Fos protein immunoreactive neurons in cingulate cortex, primary somatosensory area and hippocampus peaked at 1 day after visceral pain stimuli and reached almost normal conditions at 7 days. 3) The numbers of c-Fos protein immunoreactive neurons of somatic pain groups were higher than that of visceral groups at all times and the difference of numbers peaked at 2 hours after pain stimuli. CONCLUSION: Reactions of somatic pain stimuli influenced more changable than visceral pain stimuli to brain. Conduction velocities of somatic pain were more faster than those of visceral pain. Higher numbers of c-Fos protein immunoreactive neurons were found in specific regions. These results provide some basic knowledge in understanding the mechanism and control of pain.
Animals
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Brain*
;
Formaldehyde*
;
Gyrus Cinguli
;
Hippocampus
;
Humans
;
Male
;
Neurons*
;
Nociceptive Pain
;
Rats*
;
Rectum
;
Visceral Pain
4.Functional Evaluation of Tumor Prosthetic Arthroplasty for the Malignant Bone Tumor around the Knee: Interim Report
Joo Chul IHN ; Il Hyung PARK ; Dong Kyu SHIN
The Journal of the Korean Orthopaedic Association 1994;29(4):1109-1119
With the recent development of tumor prosthesis, limb salvage technique has attributed to the preservation of the limb function in patients with malignant bone tumors around the knee without substantial difference of local recurrence and the survival rate. From Feb., 1991 to Sep., 1992, 9 patients were treated with limb salvage operation with total knee arthroplasty due to the malignant bone tumor around the knee at Dept. of Orthopedic Surgery, Kyungpook National University Hospital. We applied the above procedure mainly to young adult whose tumor was expected to be excised wide marginally without damaging major neurovascular structures. We evaluated the functional status of all 9 patients(4 osteosarcoma, 2 chodrosarcoma, 2 malignant fibrohistiocytoma, 1 malignant giant cell tumor) to estimate the efficacy of limb salvage operation with tumor prosthesis total knee arthroplasty. Mean follow up period was 10 months. Primary tumor site was 4 in distal femur, 5 in proximal tibia and stage was 4 IIa, 5 IIb. Range of the motion of knee is maximum 0°
Arthroplasty
;
Arthroplasty, Replacement, Knee
;
Artificial Limbs
;
Extremities
;
Femur
;
Follow-Up Studies
;
Giant Cells
;
Gyeongsangbuk-do
;
Humans
;
Knee
;
Limb Salvage
;
Methods
;
Orthopedics
;
Osteosarcoma
;
Prostheses and Implants
;
Recurrence
;
Survival Rate
;
Tibia
;
Young Adult
6.Treatment of unstable pelvic ring fracture.
Dong Bae SHIN ; Pil Gu YI ; Young Kyu LEE ; Dong Hoon SON
The Journal of the Korean Orthopaedic Association 1993;28(7):2532-2539
No abstract available.
7.Influence on Changing of Area of Spinal Canal after Reduction by Posterior instrumentation in Thoracolumbar & Lumbar Burst Fractures
Dong Bai SHIN ; Jang Yeub AHN ; Young Kyu LEE ; Dong Hoon SON
The Journal of the Korean Orthopaedic Association 1994;29(4):1142-1150
There have been many debates concerning operative decompression of treatment of thoracolumbar burst fractures with retropulsed bone fragment. From March 1988 to February 1992, authors treated thirty-three thoracolumbar burst fractures by using transpedicular screw fixation and posterior fusion via the posterior approach. We attempted to reduce retropulsed fragment by ligamentotaxis alone and not to do posterolateral nor anterior decompression. After the reduction of fractured spine by posterior instrumentation, we tried to determine the efficiency of reduction of the retropulsed fragment by ligamentaxis along. As a method, we compared the change of anteroposterior, transverse to diameter and area of spinal canal of fractured spine between preoperative and the postoperative situation. The results were as follows; 1. The mean anteroposterior and transverse diameter of the spinal canal on computed tomogram film was 10.1mm & 21.8mm preoperatively & 12.4mm & 23.2mm postoperatively, showing an increase. 2. The area of spinal canal of involved spine on CT film was evaluated preoperatively & post-operatively, the mean spinal canal invasion rate decreased from 36.3% preoperatively to 14.3% postoperatively. 3. The degree of reduction of middle height on plain x-ray and reduction of spinal canal invasion on computed tomogram were statistically correlated(p < 0.01). 4. There was no correlation between the degree of canal narrowing and degree of neurologic impairment. also, there was no correlation between the reduction of retropulsed fragments and subsequent neurologic impairment. 5. There was the relatively satisfactory enlargement of the spinal canal on computed tomogram at the follow-up So we suggest that it is possible to get enough decompression through reduction of retropulsed fragment by ligamen to taxis alone without posterolateral decompression.
Decompression
;
Follow-Up Studies
;
Methods
;
Spinal Canal
;
Spine
8.Change of Femoral Anteversion during Closed Femoral Intramedullary Nailing
Kyu Hyun YANG ; Dae Yong HAN ; Dong Eun SHIN ; Dong Min KANG
The Journal of the Korean Orthopaedic Association 1996;31(2):218-224
Average anteversion of the femur is 15.3 degree. Ultrasound, computerized tomogram, and three dimensional reconstruction from CT or MRI have been used for more accurate measurement of the anteversion. There are two methods in measuing anteversion angle from CT scan:one is by drawing a mid line through long axis of the femoral neck (conventional method). Another is by drawing a line from the center of the head to that of the neck at the base of the trochanter using several cut slices (Murphy’s method). We compared these methods with fluoroscopic measurement of the Anteversion. We traced the change of the anteversion before and after closed femoral intramedullary (IMO) nailing to evaluate the origin of malrotation of the femur. 1. Normal anteversion angles were measured in 15 cases. Average anteversion angle was 6.9 degrees by conventional method, 12.3 degrees by Murphy’s method, and 12.2 degrees by fluoroscope. 2. Anteversion angles were measured after IM nailing in 18 cases. Average was 17 degrees by Murphy’s method and 15.2 degrees by fluoroscope. Mean of difference between these two methods sea 6.3 degrees. That was 1.7 degrees in normal side. 3. Change of the anteversion angle between before and after IM nailing was measured in 17 cases by fluoroscope. Average anteversion angle before the operation was 11.9 degrees and it was change to 15.8 degrees after operation. Mean of these change was 7.1 degrees. 4. Pereperative traction provides important information on change of anteversion. Reduction excessive flexion of proximal fragment was a origin of change of anteversion during nailing procedure. Conclusion : Malrotation of the femur after IM nailing must be keep in mind and it may be preventable by fluoroscopic control of the rotation in nailing procedure.
Femur
;
Femur Neck
;
Fracture Fixation, Intramedullary
;
Head
;
Magnetic Resonance Imaging
;
Methods
;
Neck
;
Traction
;
Ultrasonography
9.Quality of Life after Total Knee and Total Hip Replacement.
Dong Heon KIM ; Kyu Chul SHIN ; Byeong Chun CHANG ; Dong Hyeuk KIM
Journal of the Korean Knee Society 1998;10(1):7-12
We reviewed 40 consecutive patients having a primary total hip replacement(THR) and 60 patients having a primary total knee replacement(TKR) for osteoarthritis to compare the qu;dity of hfe(QoL) before and after operation. Bilateral arthroplasties were perfomed 10 cases of THR and 25 cemes of TKR. We used a modified Harris hip score and a knee score of American knee society, the Rosser Lndex Matrix and authors eval- uation system to generate these scores. Quality of life was highly improved by Rossers and authors evalua- tion system after THR and TKR. The median values of QoL scores before and after operation were signifi- cantly different(p<0.05). The median preoperative QoL score in THR was t>etter than in TKR. Postoperative QoL scores for both groups were similar. Quality of life evaluated by Rossers score and authors evaluation system in bilateral THR was better than bilateral TKR. We think better quality of life in bilateral THR over bilateral TKR by authors evaluation system is because the hip joint is mcire stable and has better range of motion than knee joint. We conclude that change of life style including the use of bed, toilet seat elevation, and the use of dinning table will be neccesary after bilateral TKR.
Arthroplasty
;
Arthroplasty, Replacement, Hip*
;
Climacteric
;
Hip
;
Hip Joint
;
Humans
;
Knee Joint
;
Knee*
;
Osteoarthritis
;
Quality of Life*
;
Range of Motion, Articular
10.A clinical review of the surgical treatment for pulmonary tuberculo- sis.
Cheol Shick SHIN ; Hyo Kyu JO ; Dong Cheol JANG ; Young Jun KIM ; Seok Shin KOH ; Sun Dae SONG
Tuberculosis and Respiratory Diseases 1991;38(3):245-249
No abstract available.