Interleukin-6(IL-6) is a multifunctional cytokine, and deregulated IL-6 gene expression has been implicated as being involved in the pathogenesis of a number of diseaaes. So we measured the serum level of IL-6 to find a relationahip between uterine cervical cancer and serum IL-6 level. The serum levels of IL-6 were meesured m 54 patients adrnitted to the Severance hospital, from August, 1992 to February, 1993, of whom 27 patients were diagnosed as invasive cancer of cervix, 17 as CIN, and also utilizing 10 patiente diagnosed as uterine myoma as a control group for matched age and parity. The average serum level of IL-6 in invasive cancer, CIN, and uterine myoma were respectively 30.33pg/ml, 37.27pg/ml, and 12.45pg Jml. In 22% af cervical cancer patients (6 of 27), and 27% of CIN patients (4 of 17) studied blood levels of II-6 were detected whereas only 10% of uterine myoma (1 of 10) shorved the same result. However, the difference does not seem to be statistically significant, There was no statistically significant difference among any of the groups, and age and stage did not show any significant cmrelation, and the results need furt,ber investigations.
Cervix Uteri* ; Female ; Gene Expression ; Humans ; Interleukin-6* ; Leiomyoma ; Parity ; Uterine Cervical Neoplasms

The treatment of supracondylar fracture of the femur remains a difficult problem because of the wide range of portential complications. In the past, authors thought conservative treatment was superior to operative treatment of supracondylar fracture of the femur. In addition, the advent of the Cast-Brace introduced the change in concept of the conservative treatment. Recently, however, the advances in the techniques and in the devices used in intemal fixation have encouraged the operative treatment. Tibiofemoral angle, gap or stepping of the articular surface of the distal femur, range of motion of the knee, and pains in the knee were used to evaluate the following results investigated by statistical study(T-test). These clinical results were shown by analyzing 49 cases of supracondylar fracture of the femur trea ted in the Department of Orthopedic Surgery, Hallym College of Medicine, from Jan. 1980 to Dec. 1983 1. We end result of each patient was evaluated by scaled score value calculated from above mentioned criteria. 2. The mean value of the operative treatment(35 cases) was 31.03±5.52, while that of the conservative treatment(14 cases) was 27.71±4.56. 3. The mean value of the group which began the exercise of the knee joint within 2 weeks (33 cases) was 32.24±4.43. The mean value of the other group which began the exercise of the knee joint after 2 weeks(16 cases) was 25.78±4.56. This difference of means between two groups was statistically significant. Beginning the knee joint exercise within 2 weeks has large effect on the result of the treatment. 4.The results of treatment in patient over age of 50 were graded as fair irrespective of methods of treatment. 5. Various devices were used in intemal fixation but there was no difference in the results. 6. We mean value of the Tibiofemoral angle(difference from normal angle) in the operative treatment was 2.37±6.25 and that of the conservative treatment was 8.04±4.62. Both of the above method of treatment showed a varus trend, especially in the conservative treatment. In statistical study, through, there was no significance in two methods.
Adult ; Femur ; Humans ; Knee ; Knee Joint ; Methods ; Orthopedics ; Range of Motion, Articular ; Statistics as Topic

PURPOSE: To evaluate the characteristics of CT findings in differential diagnosis of cervical lymphadenopathy. MATERIALS AND METHODS: We evaluated CT findings of histopathologically proved 32 cases of tuberculous lymphadenitis, 12 cases of nodal lymphoma, 29 cases of metastasis from March 1986 to Dec. 1992, retrospectively. We analyzed age and sex distribution, location of lymphadenopathy, internal nodal density, feature of contrast enhancement, extracapsular spread and nodal calcification. RESULTS: Tuberculous lymphadenitis was more preponderant in young female (mean;32) and CT showed internal low density(91%) with irregular thick marginal enhancement(46.9%), predilection for spinal accessory node(71.9%), and nodal calcification(5/32). Nodal lymphoma showed predilection for internal jugular chain (100%) and had conglomerated homogeneous internal node structures(83%). Metastasis showed old male preponderance (mean :52 years), predilected at internal jugular chain(89.7%),internal low density(93.3%) with regular thin marginal enhancement(44.8%), extracapsular spread(41.4%), and nodal calcification(2 cases of nodal metastasis of papillary type thyroid cancer). CONCLUSION: We concluded that CT evaluation of the chracteristics of lymphadenopathy is helpful for differential diagnosis of cervical lymphadenopathy.
Diagnosis, Differential* ; Female ; Humans ; Lymphatic Diseases* ; Lymphoma ; Male ; Neoplasm Metastasis ; Retrospective Studies ; Sex Distribution ; Thyroid Gland ; Tuberculosis, Lymph Node

No abstract available.
HLA Antigens* ; Humans

Familial lichen planus is an uncommon disease, and there are 104 cases reported in the English literature. Several theories regarding the etiopathogenesis of lichen planus have been proposed. However, immunological mechanisms and genetic susceptibility have been emphasized the most. Several reports showed HLA analysis in lichen planus patients, and recently 2 cases have revealed an increased frequency of DR1 antigen in patients with lichen planus compared to a control group. We observed two brothers with typical skin lesions of lichen planus of almost simultaneous onset. We confirmed lichen planus by skin biopsies in both brothers and analyzed HLA typing. We also observed the occurrence of DR1 antigen in both of them.
Biopsy ; Genetic Predisposition to Disease ; Histocompatibility Testing ; Humans ; Lichen Planus* ; Lichens* ; Siblings ; Skin

The purpose of this study was to compare the fitness of the IPS Empress ceramic crowns according to margin type such as bevel, shoulder, rounded shoulder, shoulder with bevel, rounded shoulder with bevel and grooved bevel. After 10 experimental dies were constructed for each group, the IPS Empress ceramic crowns were fabricated on the dies, cemented with resin cement(Bistite resin cement, Tokuyama Soda Co. Ltd., Japan) and embeded in clear epoxy resin. Each specimen was sectioned with a low speed diamond saw in both the faciopalatal and the mesiodistal direction. The cement film thickness was measured with a measuring microscope. The obtained results were as follows : 1. The fitness at the external margin was good in the following order: rounded shoulder(28.99), shoulder with bevel(31.33), grooved bevel(31.79), rounded shoulder with bevel(34.65), bevel(35.02) and shoulder(35.08). However there is no significant statistical difference. 2. The fitness at the internal margin of bevel(25.75), rounded shoulder(31.24), shoulder with bevel(32.07) and rounded shoulder with bevel(34.45) was better than that of shoulder(47.98). 3. The fitness at the axial surface of bevel(26.58) was better than that of shoulder(49.59). 4. The fitness at the central fossa was good in the following order: shoulder with bevel(38.88), grooved bevel(40.46) rounded shoulder with shoulder(46.29), shoulder(48.91), bevel(49.47) and rounded bevel(52.07). However there is no significant statistical difference. 5. Overall fitness of bevel(29.71), rounded shoulder(32.49) and shoulder with bevel(34.47) was better than that of shoulder(44.73).
Ceramics* ; Crowns* ; Diamond ; Resin Cements ; Shoulder

No abstract available.
Androgen-Insensitivity Syndrome* ; Male

Since osseous healing in the fracture of the femoral neck is carried out by endosteal bone formation, the size of contact area of the fracture fragments and impaction are of prime importance. It is not uncommon to be faced with the problem of back out of the internal fixation devices during healing period. It seems unnecessary to emphasize the benefit of sliding to close the gap between the fracture fragments. We report a retrospective study of 25 cases of the femoral neck fractures treated by closed reduction and fixation with multiple Knowles pins, paying particular attention to the amount and duration of sliding back out of the fixation devices and relating these to the final results of fracture union. Our clinical study led us to the following conclusions; 1. The shortoning of the femoral neck over 3mm occurred in 16 cases(64%) out of 25 cases. The average amount of back out of Knowles pin is 6mm. 2. Most of the shortening occurred during the first 8 weeks after surgery and extrusion of the nail is frequent findings in unstable fractures and osteoporoses. 3. Backing out over 12 weeks after surgery was associated frequently with delayed union and non-union. 4. Collapse or shortening is nceessary to promote a bone to bone contact and bone healing.
Clinical Study ; Femoral Neck Fractures ; Femur Neck ; Internal Fixators ; Osteogenesis ; Osteoporosis ; Retrospective Studies

No abstract available.
Mucocele* ; Sphenoid Sinus*

Deep vein thrombosis is a frequently lethal complication following musculoskeletal surgery and skeletal trauma. For this study on incidence of deep vein thrombosis, we examined the data on 40 patients with contrast venography. Thrombosis limited to the veins in the calf of the leg was shown in 10 patients by venography. None of these patients had clinical symptoms of deep vein thrombosis or indicating embolism. We therefore concluded that the incidence of deep vein thrombosis of the lower extremity after injury or operation in Korea is not so rare as was considered before.
Embolism ; Humans ; Incidence ; Korea ; Leg ; Lower Extremity ; Phlebography ; Thrombosis ; Veins ; Venous Thrombosis