Tracheobronchial aspergillosis is an unusual form of invasive aspergillosis characterized by noninvasive or only superficially invasive tracheobronchitis with a propensity for dissemination. We report a two-year-old male who suddenly died of respiratory failure. Postmortem examination revealed a pseudomembrane covering the mucosa of larynx, trachea and bronchial tree of both lungs. This pseudomembrane was composed predominantly of Aspergillus hyphae. There was transmural necrotizing bronchitis with fungal invasion to the narrow zone of peribronchial tissue, and dissemination to the stomach and kidney. This form of pulmonary aspergillosis had not been reported in this country.
Aspergillosis* ; Aspergillus ; Autopsy* ; Bronchitis ; Humans ; Hyphae ; Kidney ; Larynx ; Lung ; Male ; Mucous Membrane ; Pulmonary Aspergillosis ; Respiratory Insufficiency ; Stomach ; Trachea

No abstract available.
Antibodies*

No abstract available.
Female ; Humans ; Urodynamics* ; Uterine Prolapse*

An isolated granulocytic sarcoma (chloroma) of the left ovary occured in the absence of leukemia in a 12-year-old woman. This lesion is defined as a localized tumor mass composed of immature cells of the granulocytic series. Granulocytic sarcomas can occur at extramedullary sites including ovary but, isolated myelosarcoma in the absence of usual manifestations of AML may be rare and has some difficulties in diagnosis. Contrary to findings in other series, granulocytic sarcoma arising in this nonleukemic patient did not progress to acute leukemia during two years she has been followed.
Child ; Diagnosis ; Female ; Humans ; Leukemia ; Ovary* ; Sarcoma, Myeloid*

BACKGROUND: Propofol has a high incidence of pain with intravenous injection, and different methods have been used to minimize the incidence and severity of this pain. In this study, we have compared the effect of lidocaine pretreatment with that of ketamine pretreatment on propofol injection pain. METHODS: Ninety healthy female patients scheduled for general anesthesia were randomly divided into three groups; saline group (n=30), lidocaine group (n=30) and ketamine group (n=30). Each patient received 2 ml of pretreatment solution (normal saline, 1% lidocaine, 0.5% ketamine) via 18G angiocatheter inserted in the antecubital fossa after applying an arm tourniquet inflated to 50 mmHg. The tourniquet was released 1 minute later, followed by intravenous injection of 2.5 mg/kg of propofol. The assessment of pain was made at the induction of anesthesia and in the recovery room, and the severity of pain was classified as none, mild, moderate, severe by one observer. RESULTS: The severity and incidence of pain diminished significantly in the lidocaine group and the ketamine group compared with the saline group at the induction of anesthesia (p<0.05) and there was no significant difference between the lidocaine group and the ketamine group. We had similar results in the recovery room and one patient from the saline group and the ketamine group had no recall regarding injection pain. CONCLUSION: Intravenous ketamine pretreatment is as effective as intravenous lidocaine pretreatment in alleviating the propofol injection pain.
Anesthesia ; Anesthesia, General ; Arm ; Female ; Humans ; Incidence ; Injections, Intravenous ; Ketamine* ; Lidocaine* ; Propofol* ; Recovery Room ; Tourniquets

Interstitial cystitis is prevalent in the 5th decade women, characterized by frequency, urgency and pelvic pain. To diagnose interstitial cystitis, NIH diagnostic criteria was used. Patients underwent overdistention and all patients were evaluated with IPSS symptom score and urodynamic study in preoperative period, post operative(POD) 1 week and 1 month. The age distribution was 4th decade in 1 patient, 5th decade in 3, 6th decade in 2, 7th decade in 4 and then above 7th decade in 2. Symptom durations was less than 7 years in 7 patients, between 7-10 years in 2 and more than 10 years in 3. Changes in bladder irritative symptom score between preop. and POD 1 week, and preop. and POD 1 month were 6.00+/-4.40(p<0.05) and 6.36+/-2.29(p<0.05) with statistical significance, respectively. Changes in obstructive symptom scores were 4.91+/-4.27(P<0.05) and 3.91+/-4.76(P<0.05) with statistical significance. On urodyna-mic study, the volume of first voiding sensation between preop and POD 1 week was 29.45+/-52.04(p>0.05) but statistically insignificant. However, the change between pre op. and POD 1 month was 97.45+/-90.29(p<0.05) with statistical significance. Difference in maximal capacity between preop. and POD 1 week was statistically significant as 87.55+/-126.39(p<0.05). Bladder functional capacity changes between with and without anesthesia was statistically significant(p<0.05) Postop. complications were bladder rupture in 1 case, and hematuria in 12. The results of overdistention was useful in the diagnosis and treatment of interstitial cystitis. Then more evaluation and follow up will be needed.
Age Distribution ; Anesthesia ; Cystitis, Interstitial* ; Diagnosis ; Female ; Follow-Up Studies ; Hematuria ; Humans ; Pelvic Pain ; Preoperative Period ; Rupture ; Sensation ; Urinary Bladder ; Urodynamics

Torsion of the testis is a common urological emergency. We treated 28 cases of spermatic cord torsion during the period from March. 1978 to November, 1988. Detorsion with orchiopexy was performed in 19 cases, remaining cases underwent orchiectomy. Follow up was made in 13 cases who underwent detorsion with orchiopexy, and 11 cases of them under went testicular biopsy at same operation field. histopathologic findings of testicular biopsies were compared with clinical characteristics and courses of patients. The results were as follows : 1. Among the group of biopsy, testicular atrophy occurred in 5 cases and normal testis was palpable in 6 cases 2. Testicular salvage is closely related with duration of symptoms. 3. Histopathologic findings of atrophic testis group showed marked hemorrhagic necrosis of seminiferous tubule and interstitial tissue, but normally palpable testis group showed mild to moderate congestive and hemorrhagic changes of seminiferous tubule and interstitial tissue. 4. histopathologic changes were more deteriorative in the group of patients more delayed managed. 5. We could predict fate of testis after orchiopexy by biopsy findings.
Atrophy ; Biopsy* ; Emergencies ; Estrogens, Conjugated (USP) ; Follow-Up Studies ; Humans ; Necrosis ; Orchiectomy ; Orchiopexy ; Seminiferous Tubules ; Spermatic Cord Torsion* ; Spermatic Cord* ; Testis

No abstract available.
Indicators and Reagents*

No abstract available.
Indicators and Reagents*

No abstract available.
Humans ; Hyperbilirubinemia, Hereditary* ; Siblings*