No abstract available.
Penicillamine*

Large cell neuroendocrine carcinoma (LCNEC) of the lung is a newly recognized entity of pulmonary neuroendocrine carcinoma. Histologically, it is very difficult to differentiate LCNEC from other pulmonary carcinomas and the prognosis is significantly poor. The cutaneous metastasis of LCNEC of the lung shares some features with Merkel cell carcinoma of the skin in light microscopy and yet it is negatively stained with cytokeratin 20. We report a case of cutaneous metastasis of LCNEC of the lung, previously misdiagnosed as squamous cell carcinoma. Our patient showed a poor response to the chemotherapy and also revealed a brain metastasis on follow-up brain CT scan.
Brain ; Carcinoma, Merkel Cell* ; Carcinoma, Neuroendocrine* ; Carcinoma, Squamous Cell ; Drug Therapy ; Follow-Up Studies ; Humans ; Keratin-20 ; Lung* ; Microscopy ; Neoplasm Metastasis ; Prognosis ; Skin ; Tomography, X-Ray Computed

No abstract available.

Healthcare system in Korea was found to be very vulnerable to public health emergency preparedness and response as demonstrated in the recent outbreak of Middle East Respiratory Syndrome Coronavirus. We need to redefine the function of and improve the capability of local district public hospital and local health center to cope with potential threats by newly emerging infectious disease in the nearer future. While central government may be responsible for early detection of newly emerging infectious disease transmitted from outside of the country, local government and its district-level public healthcare agencies need to primarily control over spread of the disease among the local residents. Governance setting for rapid response required in public health crisis situation appears to be possible based on strong local public health infrastructure for health promotion and disease prevention at si-gun-gu district level. Proper and sustainable investment is also needed for local public hospital with high standard facilities and skilled healthcare manpower since there seems little economic incentives to maintain such facilities in private hospitals. In conclusion, it would be urgent task to improve prevention activities for infectious disease of local health centers and clinical activities of local public hospital. Especially, role and competencies of public health physicians working at the public health center need to be specified as an essential component of public health infrastructure.
Civil Defense ; Communicable Diseases ; Communicable Diseases, Emerging* ; Coronavirus ; Delivery of Health Care ; Disease Outbreaks ; Health Promotion ; Hospitals, Private ; Hospitals, Public* ; Investments ; Korea* ; Local Government ; Middle East* ; Motivation ; Public Health

No abstract available.

Bietti's crystalline retinopathy is a rare form of tapetoretinal degeneration characterized by yellow, polygonal, glistening intraretinal crystals in the posterior pole and in the superficial paralimbal cornea, which may be due to a systemic abnormality of lipid metabolism, and has been to have a autosomal recessive pattern.Also lots of the reports described similar cases without any corneal changes. 56 years-old female with complaint of progressive visual decrease had corrected visual acuity of 0.1 in her right eye and 1.0 in her left eye.Yellow intraretinal crystals with retinal pigment epithelial (RPE)dystrophy and choroidal sclerosis were noticed without any corneal changes.During follow-up for thirty months, visual acuity gradually decreased to counting fingers in her right eye and 0.7 in her left eye, and RPE degeneration and choroidal sclerosis worsened with no change in intraretinal crystals.
Choroid ; Cornea ; Crystallins* ; Female ; Fingers ; Follow-Up Studies ; Humans ; Lipid Metabolism ; Middle Aged ; Retinaldehyde ; Retinitis Pigmentosa ; Sclerosis ; Visual Acuity

No abstract available.
Granuloma Annulare* ; Granuloma* ; Herpes Zoster*

Surgical treatment is recommended in tricuspid valve endocarditis not responding to antibiotics or presenting severe heart failure. However, risk of early prosthetic valve endocarditis especially in drug addictors is principal concern in the treatment. A 37 year-old man with tricuspid valve endocarditis underwent staged operation of primary tricuspid valvulectomy and secondary bioprosthetic valve implantation successfully. We report it with references of literature.
Adult ; Anti-Bacterial Agents ; Endocarditis* ; Heart Failure ; Humans ; Tricuspid Valve

No abstract available.
Genitalia* ; Poroma*

BACKGROUND: The goal of this study was to evaluate whether a modified fluoroscopic technique for positioning a hook plate affected the clinical results of treating Neer type II distal clavicle fractures and Rockwood type V acromioclavicular (AC) joint separations with this device. METHODS: The study was a retrospective consecutive case series with data analysis. Sixty-four patients with a Neer type II distal clavicle fracture or a Rockwood type V AC joint injury treated between March 2009 and June 2013 were divided into 2 groups: traditional fluoroscopic technique (traditional view, 31 patients) or modified fluoroscopic technique ('hook' view, 33 patients). A visual analogue scale (VAS) score, the modified University of California-Los Angeles (UCLA) shoulder scale score, and radiographic osteolysis were the main outcome measures. RESULTS: The traditional group included a significantly larger number of patients with acromial osteolysis than the hook view group: 23 patients (74.2%) vs. 11 patients (33.3%), respectively (p=0.01). Before plate removal, the hook group reported less pain and higher UCLA shoulder scale scores than the traditional group: average VAS score, 1.55 vs. 2.26, respectively; average UCLA score, 30.88 vs. 27.06, respectively. However, there was no significant difference after plate removal. CONCLUSIONS: The hook view allows more accurate bending of the hook plate around the contour of the acromion, resulting in decreased osteolysis, decreased pain, and better function with the plate in situ.
Acromioclavicular Joint ; Acromion ; Clavicle* ; Dislocations ; Humans ; Joints ; Osteolysis ; Outcome Assessment (Health Care) ; Retrospective Studies ; Shoulder ; Statistics as Topic