1.Alzheimer’s Disease Prediction Using Attention Mechanism with Dual‑Phase 18 F‑Florbetaben Images
Nuclear Medicine and Molecular Imaging 2023;57(2):61-72
Materials and Methods:
A total of 264 patients (74 CN and 190 AD), who underwent FBB imaging test and neuropsychological tests, were retrospectively analyzed. Early- and delay-phase FBB images were spatially normalized with an in-house FBB template. The regional standard uptake value ratios were calculated with the cerebellar region as a reference region and used as independent variables that predict the diagnostic label assigned to the raw image.
Results:
AD positivity scores estimated from dual-phase FBB showed better accuracy (ACC) and area under the receiver operating characteristic curve (AUROC) for AD detection (ACC: 0.858, AUROC: 0.831) than those from delay phase FBB imaging (ACC: 0.821, AUROC: 0.794). AD positivity score estimated by dual-phase FBB (R: −0.5412) shows a higher correlation with psychological test compared to only dFBB (R: −0.2975). In the relevance analysis, we observed that LSTM uses different time and regions of early-phase FBB for each disease group for AD detection.
Conclusions
These results show that the aggregated model with dual-phase FBB with long short-term memory and attention mechanism can be used to provide a more accurate AD positivity score, which shows a closer association with AD, than the prediction with only a single phase FBB.
2.Family’s Perception of Proxy Decision Making to Authorize Do Not Resuscitate Order of Elderly Patients in Long Term Care Facility: A Q-Methodological Study
Journal of Korean Academy of Nursing 2021;51(1):15-26
Purpose:
This study aimed to distinguish and describe the types of perceptions of do not resuscitate (DNR) proxy decisions among families of elderly patients in a long-term care facility.
Methods:
This exploratory study applied Q-methodology, which focuses on individual subjectivity. Thirty-four Q-statements were selected from 130 Q-populations formed based on the results of in-depth interviews and literature reviews. The P-samples were 34 families of elderly patients in a long-term care hospital in Busan, Korea. They categorized the Q-statements using a 9-point scale. Using the PC-QUANL program, factor analysis was performed with the P-samples along an axis.
Results:
The families’ perceptions of the DNR proxy decision were categorized into three types. Type I, rational acceptance, valued consensus among family members based on comprehensive support from medical staff. Type II, psychological burden, involved hesitance in making a DNR proxy decision because of negative emotions and psychological conflict. Type III, discreet decisions, valued the patients’ right to self-determination and desire for a legitimate proxy decision. Type I included 18 participants, which was the most common type, and types II and III each included eight participants.
Conclusion
Families’ perceptions of DNR proxy decisions vary, requiring tailored care and intervention. We suggest developing and providing interventions that may psychologically support families.
3.Ultrasonographic and CT Findings of Hepatosplenic Tuberculosis.
Un Hyeon MOON ; Jeong Seok LEE ; Kang Seok KO ; Byung Ran PARK ; Dong Cheol YANG ; Ju Hyeon IM ; In Young KANG
Journal of the Korean Radiological Society 1998;39(2):345-351
PURPOSE: To evaluate the ultrasonographic and CT findings of hepatosplenic tuberculosis MATERIALS AND METHODS: We retrospectively reviewed the ultrasonographic and CT findings of confirmed hepatosplenic tuberculosis in 12patients. Six were men and six were women ; their average age was 41, and most were in their twenties. Lesions ofthe liver and spleen, as well as associated findings such as abdominal tuberculosis and other organ involvement oftuberculosis were analyzed. RESULTS: There were three cases of hepatic tuberculosis, seven of splenictuberculosis, and two of hepatosplenic involvement of tuberculosis. On the basis of the ultrasonographic and CTfindings, hepatosplenic tuberculosis was classified as one of two patterns : miliary or micronodular, ormacronodular. The micronodular type was more common (9/12 cases) being characterized by innumerable micronodules,and with easy coalescence in the liver and spleen in five of the nine cases. The macronodular type of low densitymass was noted in the other three patients. Splenomegaly was noted in 12 cases and hepatomegaly in ten. Pulmonarytuberculosis-including the miliary type(n=5)-was noted in eight patients. Associated abdominal tuberculosis suchas lymphadenopathy with central low density and peripheral rim enhancement (n=6), tuberculous peritonitis(n=3),highly attenuated ascites(n=6), adrenal tuberculosis(n=1), renal tuberculosis(n=1), ovarian abscess(n=1), psoasabscess(n=1), and systemic tuberculosis such as central nervous system tuberculoma(n=2), cervicallymphadenopathy(n=4) and tuberculous spondylitis(n=1) were noted. CONCLUSION: Ultrasonography and CT werevaluable in the detection and diagnosis of hepatosplenic tuberculosis
Central Nervous System
;
Diagnosis
;
Female
;
Hepatomegaly
;
Humans
;
Liver
;
Lymphatic Diseases
;
Male
;
Retrospective Studies
;
Spleen
;
Splenomegaly
;
Tuberculosis*
;
Tuberculosis, Gastrointestinal
;
Tuberculosis, Hepatic
;
Ultrasonography
4.A Case of Giant Multilocular Prostatic Cystadenoma.
Hee Tak YANG ; Jeong Su KANG ; Dong Goo KANG ; Jang Wook SONG ; Ho Hyeon JEONG ; Nak Gyeu CHOI
Korean Journal of Urology 2000;41(6):791-793
No abstract available.
Cystadenoma*
5.A Case of Giant Multilocular Prostatic Cystadenoma.
Hee Tak YANG ; Jeong Su KANG ; Dong Goo KANG ; Jang Wook SONG ; Ho Hyeon JEONG ; Nak Gyeu CHOI
Korean Journal of Urology 2000;41(6):791-793
No abstract available.
Cystadenoma*
6.Transperineal Sonography of the Prostate in the Patients with Abdominoperineal Resection.
Jung Suk LEE ; Byung Ran PARK ; Un Hyeon MOON ; Dong Cheol YANG ; Joo Hyeon IM ; In Yeong KANG
Journal of the Korean Radiological Society 1998;39(6):1203-1207
PURPOSE: To evaluate the usefulness of transperineal sonography of the prostate in patients with previousabdominoperineal resection. MATERIALS AND METHODS: Transperineal prostatic sonograms were obtained from ninepatients with abdominoperineal resection. The shortest distance between the probe and the prostate gland, itsvolume, and its internal and external structures were evaluated for image quality, shape, border, and the degreeof distortion in internal echo. Because the number of patients was small, statistical analysis was not performed. RESULTS: Transperineal sonography of the prostate in eight patient was obtained at ease, except that one of ninepatients was not able to continue the procedure because of severe tenderness of the perineum and poor cooperation.Acceptable images of the prostate gland and their adjacent structures were obtained in one patient with less than1cm between the probe and prastate gland, three of four with between 1cm and 1.5cm, and one of three with morethan 1.5cm. CONCLUSION: In patients with previous abdominoperineal resection, transperineal sonography of theprostate may be a good imaging modality.
Humans
;
Perineum
;
Prostate*
7.Immediate effect of cigarette smoking on exercise.
Kang Hyeon CHOE ; Cheol Jun CHOI ; Yong Tae KIM ; Chae Man LIM ; Younsuck KOH ; Woo Sung KIM ; Won Dong KIM
Tuberculosis and Respiratory Diseases 1992;39(6):511-516
No abstract available.
Smoking*
;
Tobacco Products*
8.Hemodynamic Effect of Prazosin in Congestive Heart Failure.
Jin Won JEONG ; Hyeon KWON ; Dong Hee YANG ; Sang Myung LEE ; Jung Chaee KANG ; Ock Kyu PARK
Korean Circulation Journal 1982;12(2):181-186
The hemodynamic effects of Prazosin were evaluated in 31 cases with congestive heart failure (mitral stenosis; 15 cases, mitral insufficiency; 7 cases, hypertensive heart disease;4 cases, congestive cardiomyopathy; 5 cases) by means of echocardiographic method. Before and 90 min. after the administration of prazosin(3mg p.o.), M-mode echocardiograms of left ventricle were recorded, from which end-diastolic and end-systolic dimensions of left ventricle and left ventricular ejection time were measured. Hemodynamic parameters of left ventricular performance, i.e., mean veloity of circumferential fiber shortening, fractional fiber shortening, ejection fraction, stroke volume, and cardiac output were calculated from the measurements. Left ventricular end-diastolic and end-systolic dimensions were decreased significantly after prazosin administration and left ventricular performance was significantly increased after prazosin administration, whereas stroke volume was not. Total systemic peripheral resistance and mean arterial pressure showed no significant changes. All cases, except one of the patients showed marked symptomatic relief after prazosin administration evaluated by NYHA functional classification. There was no considerable untoward effect in the patients of congestive heart failure to whom the prazosin was administered.
Arterial Pressure
;
Cardiac Output
;
Cardiomyopathy, Dilated
;
Classification
;
Constriction, Pathologic
;
Echocardiography
;
Estrogens, Conjugated (USP)*
;
Heart
;
Heart Failure*
;
Heart Ventricles
;
Hemodynamics*
;
Humans
;
Mitral Valve Insufficiency
;
Prazosin*
;
Stroke Volume
;
Vascular Resistance
9.Isolated Shoulder Weakness due to a Small Cortical Infarction.
Hyeon Uk NAH ; Hee Kyung PARK ; Dong Wha KANG
Journal of Clinical Neurology 2006;2(3):209-211
Small cortical infarctions can produce isolated motor paresis in the upper extremities. Several cases of isolated hand or finger paresis have been reported, but isolated shoulder weakness is extremely rare. We report here a patient who developed isolated shoulder weakness due to a small cortical infarction in the medial precentral gyrus.
Fingers
;
Hand
;
Humans
;
Infarction*
;
Paresis
;
Shoulder*
;
Upper Extremity
10.Finite element analysis on the connection types of abutment and fixture.
Byeong Hyeon JUNG ; Gyeong Je LEE ; Dong Wan KANG
The Journal of Korean Academy of Prosthodontics 2012;50(2):119-127
PURPOSE: This study was performed to compare the stress distribution pattern of abutment-fixture connection area using 3-dimensional finite element model analysis when 5 different implant systems which have internal connection. MATERIALS AND METHODS: For the analysis, a finite element model of implant was designed to locate at first molar area. Stress distribution was observed when vertical load of 200 N was applied at several points on the occlusal surfaces of the implants, including center, points 1.5 mm, 3.0 mm away from center and oblique load of 200 N was applied 30degrees inclined to the implant axis. The finite element model was analyzed by using of 3G. Author (PlassoTech, California, USA). RESULTS: The DAS tech implant (internal step with no taper) showed more favorable stress distribution than other internally connected implants. AS compare to the situations when the loading was applied within the boundary of implants and an oblique loading was applied, it showed higher equivalent stress and equivalent elastic strain when the loading was applied beyond the boundary of implants. Regardless of loading condition, the abutments showed higher equivalent stress and equivalent elastic strain than the fixtures. CONCLUSION: When the occlusal contact is afforded, the distribution of stress varies depending on the design of connection area and the location of loading. More favorable stress distribution is expected when the contact load was applied within the diameter of fixtures and the DAS tech implant (internal step with no tapering) has more benefits than the other design of internally connected implants.
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid
;
Axis, Cervical Vertebra
;
Bite Force
;
California
;
Dental Implants
;
Finite Element Analysis
;
Molar
;
Sprains and Strains