1.A Case of Fanconi's Anemia.
Dong Hwan CHA ; Jung Shim CHOI ; Kwang Ho KIM ; Hong Ku LEE ; Sha Sook HAHN
Journal of the Korean Pediatric Society 1983;26(8):808-811
No abstract available.
Fanconi Anemia*
2.The incidence of complications in severely obese children.
Dong Hwan LEE ; Chul LEE ; Chong Guk LEE ; Yong Seung HWANG ; Sung Ho CHA ; Yong CHOI
Journal of the Korean Pediatric Society 1991;34(4):445-453
No abstract available.
Child*
;
Fatty Liver
;
Humans
;
Hypercholesterolemia
;
Incidence*
;
Obesity
3.Clinical Efficacy of Carvedilol in Patients with Moderate to Severe Congestive Heart Failure.
Dong Hoon CHA ; Young Soo CHA ; Jin Hwan KOOK ; Kyung Wha WHANG ; Hyung Tae KIM ; Sang Wook LIM ; Tae Yong KIM ; Yun Kyung CHO ; Pil Won PARK
Korean Circulation Journal 1998;28(4):523-531
BACKGROUND: Clinical trials have shown that b-adrenergic blocking drugs are effective and well tolerated in patients with mild to moderate congestive heart failure. Carvedilol is a mild b1-selective adrenergic blocking agent with vasodilating properties due to a blocker and antioxidant and anti-proliferative properties. This study assessed the efficacy and safety of carvedilol in patients with moderate to severe congestive heart failure caused by idiopathic dilated cardiomyopathy. METHODS: We enrolled 27 patients with moderate to severe congestive heart failure with a left ventricular ejection fraction of 35% by MUGA scan. Each patient was randomly assigned to either control (n-9) or carvedilol (n-18, target dose 25 mg bid) for 6 months while background therapy with digoxin, diuretics, and ACE inhibitor remained constant. RESULTS: Compared to the control group, patients in the carvedilol group showed significant increase of left ventricular ejection fraction (p<0.05). In addition, patients in the carvedilol group had a tendency to show a decrease in left ventricular end-diastolic dimension and heart rate. Also, the carvedilol group had a greater frequency of symptomatic improvement than the control group. There was neither serious side effects nor hospitalization. CONCLUSION: These finding indicate that carvedilol produces important clinical benefits in patients with moderate to severe heart failure treated with digoxin, diuretics, and ACE inhibitor without serious side effects.
Cardiomyopathy, Dilated
;
Digoxin
;
Diuretics
;
Heart Failure*
;
Heart Rate
;
Hospitalization
;
Humans
;
Stroke Volume
4.The common orthopedic problems in parent's concern.
Dong Eun SHIN ; Byung Ho YOON ; Ju Hwan CHUNG
Korean Journal of Pediatrics 2008;51(2):122-128
Roughly one third of medical problems in children are related to the musculoskeletal system. Most of these problems are common and can be precisely diagnosed. For these problems, nonoperative treatment or reassurance can be given by the pediatrician. Occasionally, a problem needs surgical treatment, but a precise diagnosis must be made. There is little agreement about what types of orthopedic problems a primary care pediatrician should understand in order to effectively care for children. Many pediatric residencies lack an organized teaching curriculum that effectively covers these topics or that includes a required pediatric orthopedic rotation. In this article the authors delineate pediatric orthopedic problems that require recognition and urgent surgical treatment and are relatively common, but have different treatment options (observation, conservative treatment, and surgery) depending on their natural history. Whenever possible, the diagnosis should be made before a decision to refer is made. An accurate diagnosis allows the pediatrician to discuss the natural history of the condition properly. Referral to the wrong specialty can needlessly generate expensive tests and further delay in treatment or generate inappropriate treatment. The parents can be reassured rather than waiting to hear the same information from another physician. In particular, orthopedic problems are known to generate pressure from the parents to seek specialty consultation for reassurance. It is important to communicate to the specialist that the reason for the referral is for parental reassurance rather than for further work-up or treatment. After a proper diagnosis, communication directly between the pediatrician and the appropriate specialist can often avoid an unnecessary referral, and avoid unnecessary tests. The authors reviewed our experience at our outpatient clinic over last 1 year and found that it is useful to classify conditions as common or uncommon, and whether they require surgical or nonsurgical treatment. Many conditions fall in between. The following is a discussion of some of these more important or common conditions.
Ambulatory Care Facilities
;
Child
;
Curriculum
;
Humans
;
Internship and Residency
;
Musculoskeletal System
;
Natural History
;
Orthopedics
;
Outpatients
;
Parents
;
Primary Health Care
;
Referral and Consultation
;
Specialization
5.Over-the-top Augmentation with ABC Synthetic Ligament in the Treatment of Acute Rupture of Anterior Cruciate Ligament.
Dong Bae SHIN ; Young Soo LEE ; Yong Jung KIM ; Dong Eun SHIN ; Soo Hong HAN ; Jong Hwan CHA
Journal of the Korean Knee Society 1999;11(2):189-194
PURPOSE: To evaluate the clinical outcome after the over-the-top augmentation with ABC synthetic lig-ament for the treatment of acute rupture of anterior cruciate ligament at least two years follow up. MATERIALS AND METHODS: From January 1992, authors have treated acute rupture of ACL with this method on 91 cases. Among these, 46 cases were available for full data acquisition. At the last follow-up, clinical results were analyzed subjectively and objectively by Lachman, pivot shift test and presence of joint effusion. Functional evaluation was performed by various knee ligament scoring systems and the side-to-side differences were measured with KT-2000 arthrometer. RESULTS: On Lachman test, 82.7% were under grade I&II; grade 0 : 17 cases(37%), grade I: 21 cases(45.7%), grade III: 8 cases(17.3%). 89.3% were under grade 0 & Ion pivot shift test. On measure-ment of side-to-side difference, 25 cases(54.3%) were showed difference less than 3 mmand the differences of 16 cases(34.8%) were 3~5 mm. On six cases joint effusions were present. Among these six cases, four cases were accompanied by anterior instability which were brought to second look arthroscopy. Two cases were treated with several times of aspiration and steroid instillation. The one case was failed its continuity which solved with ACL reconstruction with patellar bone-tendon-bone autograft. The other three cases showed only lax ACL which was cared with retightening of ligament at the femoral attach-ment site. At the last follow up, 37 cases(80.4%) were resulted excellent and good on Lysholm score and 41 cases(89.1%) were group A & B on IKDC score. On Tegner scale, 34 cases(73.9%) were above five point. CONCLUSIONS: Authors suggest this over-the-top augmentation of ACL with synthetic polyester ligament would be good treatment option with several advantages; early rehabilitation is possible to get maximal function of knee and no tunnel in the lateral condyle would be good for late ACL reconstruction even though failure of this artificial ligament.
Anterior Cruciate Ligament*
;
Arthroscopy
;
Autografts
;
Follow-Up Studies
;
Joints
;
Knee
;
Ligaments*
;
Polyesters
;
Rehabilitation
;
Rupture*
6.Clinical results of partial zona dissection for infertility.
Sung Eun PARK ; Dong Hee CHOI ; Hwan Cheol RHO ; Jung Jae KO ; Jong Young PARK ; Kwang Yul CHA
Korean Journal of Fertility and Sterility 1993;20(1):45-51
No abstract available.
Herpes Zoster*
;
Infertility*
7.A clinical study in phenylketonuria.
Hye Kyeong NAM ; Jin Seop SHIM ; Dong Hwan LEE ; Sang Jhoo LEE ; Ki Weon CHA ; Jeong Bin YIM
Journal of the Korean Pediatric Society 1992;35(1):69-79
No abstract available.
Phenylketonurias*
8.Prenatal Cytogenetic Analysis of 145 Fetuses Conceived by Intracytoplasmic Sperm Injectiion ( ICSI ).
Sook Hwan LEE ; Ki Boong OUM ; Eun Jung LEE ; Tae Ki YOON ; Kwang Yul CHA ; In Pyung KWAK ; Dong Hee CHOI
Korean Journal of Obstetrics and Gynecology 1998;41(12):3040-3043
Prenatal diagnoses were performed in 145 fetuses resulting from 73 singleton and 36 twin pregnancies, all established by intracytoplasmic sperm injection (ICS: amniocentesis in 108 patients and Chorionic villus sampling in one. The prenatal cytogenetic results were obtained from pregnancies after ICSI using ejaculated spermatozoa, epididymal spermatozoa, testicular spermatozoa and after the replacement of frozen-thawed embryos derived from ICSI. The Karyotypes were normal in 138 cases (95.2%) of the prenatal diagnoses and there were 2 cases (1.4%) de novo and 5 cases (3.4%) inherited chromosomal aberrations. The two cases of de novo abnormalities were: 46, XY, t(6;7)(q21;p22) and 47, XY, +21 (trisomy 21).
Amniocentesis
;
Chorionic Villi Sampling
;
Chromosome Aberrations
;
Cytogenetic Analysis*
;
Cytogenetics*
;
Embryonic Structures
;
Female
;
Fetus*
;
Humans
;
Karyotype
;
Pregnancy
;
Pregnancy, Twin
;
Prenatal Diagnosis
;
Sperm Injections, Intracytoplasmic*
;
Spermatozoa*
9.A case of Congenital Osteogenesis Imperfecta.
Suck Young LEE ; Yoon Ho KANG ; Sang Keun OH ; Mi Sook PARK ; Hee Dae PARK ; Dong Hwan CHA
Journal of the Korean Pediatric Society 1986;29(5):111-114
No abstract available.
Osteogenesis Imperfecta*
;
Osteogenesis*
10.Upper Limit of Normal Value for Antistreptolysin O Titer of Healthy Children in Seoul.
Sung Ho CHA ; Yong Mook CHOI ; Sei Won YANG ; Dong Hwan LEE ; Chong Guk LEE ; Chang Ho HONG
Journal of the Korean Pediatric Society 1995;38(8):1061-1068
No abstract available.
Antistreptolysin*
;
Child*
;
Humans
;
Reference Values*
;
Seoul*