1.Cutaneous Plasmacytoma Associated with Multiple Myeloma.
Sung Ku AHN ; Seung Hun LEE ; Dong Hwan SHIN
Korean Journal of Dermatology 1987;25(6):854-857
A 52-year-old man with multiple myeloma developed cutaneous nodules while being treated with melphalan and prednisolone. A biopsy specimen showed dermal infiltration by well differentiated plasma cells similar to those found on bone marrow biopsy. The use of peroxidase anti-peroxidase to demonstrate the monoclonality or polyclonality of the cytomplasmic immunoglohulins in the tumor cells revealed a positivity for IgG and 1 chain (ie, monotypic staining). Ultrastructurally, each plasmacytoma cell contained varyting amounts of rough endoplasmic reticulum and Golgi-apparatus. The cutnneous nodules completely disappeared after radiotherapy
Biopsy
;
Bone Marrow
;
Endoplasmic Reticulum, Rough
;
Humans
;
Immunoglobulin G
;
Melphalan
;
Middle Aged
;
Multiple Myeloma*
;
Peroxidase
;
Plasma Cells
;
Plasmacytoma*
;
Prednisolone
;
Radiotherapy
2.Comparative Study of Panoramic Mandibular Parameters in Postmenopausal Osteoporotic women.
Cheol Hun KIM ; Sang Hun SHIN ; Dong Kyu YANG
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2000;26(5):519-526
Osteoporosis has recently been recognized as a major health problem in the elderly population. The disorder is manifested as a loss of bone mass accompanied by structural alteration of bone and increased incidence of fracture. Mandible also may be affected. So, I evaluated panoramic views of 66 postmenopausal women for finding the possibility of useful diagnostic mandibular parmeters of osteoporosis. To know the correlationship between skeleton and mandible, the average of the bone mineral density of lumbar from 2nd to 4th by the dual energy X-ray absorptiometry(DEXA, LUNAR DPZ. USA), and age and mandibular parameters, that is, the number of residual teeth, alveolar ridge resorption ratio, panoramic mandibular index (PMI), mandibular cortical width (MCW), angular cortical thickness (ACT), ramus cortical thickness (RCT), morphology of mandibular inferior cortical (MIC) were compared. And I divided the all tested women to the osteoporotic group and non-osteoporotic group by the use of T-score-2.0, which was derived from skeletal bone mineral density (BMD). To find the correlationship of the each group with mandibular parameters, t-test and discriminant analysis were done. The results of the t-test were that all parameters were highly related with 2 groups (p<0.05). Especially ACT, MIC, age have had even higher correlationship than others (p<0.001). The results of the discriminant analysis by the use of these ACT, MIC and age were that the discriminant function was Z =-2.973+(-1.447)x(ACT)+1.131x(MIC score)+(0.052)x(age), the cutting score was 0.257 and the classification accuracy was 84.8%. Therefore I suggest that the consideration of the angular cortical thickness (ACT), the age of patient and the morphology of mandibular inferior cortical(MIC) may help find the osteoporosis.
Aged
;
Alveolar Process
;
Bone Density
;
Classification
;
Female
;
Humans
;
Incidence
;
Mandible
;
Osteoporosis
;
Skeleton
;
Tooth
3.A study of care for diabetic patients in primary care setting.
Chang Hun CHOI ; Kyeung Yul KIM ; Chul Yung BAE ; Hang Soon SHIN ; Dong Hak SHIN
Journal of the Korean Academy of Family Medicine 1993;14(4):258-264
No abstract available.
Humans
;
Primary Health Care*
4.An Experimental Study on the Survival of Membranous Inlay Bone Graft on the Mandible.
Bong Soo BAIK ; Dong Pill SHIN ; Dong Hun LEE ; Jung Hyung LEE ; Byung Chae CHO
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(4):677-682
Bone graft is an important procedure in craniomaxillofacial reconstruction and the success of reconstruction depends on the survival of the grafted bone. In this study, the survival of the membranous inlay bone graft on the mandibles of dogs was investigated with bone scan and histologic examination. The inlay bone graft, 1x2cm critical-sized bone, was completely separated from the lower border of the mandible of dogs and then refixed to the original site. Bone scan and histologic examination were done at 1,2,3 and 4 weeks postoperatively. The bone scan after 1 week showed radioisotope uptake on the margin of the grafted bone and the isotope count was 21% compared to the uptake of the normal bone. After 2 weeks, the radioisotope uptake in the grafted bone increased to 52% of normal bone uptake. After 3 and 4 weeks, the degree of isotope uptake was 111% and 124% respectively. Histological findings after 1 week showed the absence of osteoblastic activity and 6 viable blood vessels in one 200X magnified field, which was 25% compared to the vessels of the normal bone. After 2 weeks, osteoblastic activities were noted and the number of viable blood vessels totalled 15, which was 63% of the vessels of the normal bone. After 3 weeks, osteoblastic activities increased and the number of viable blood vessels totalled 21, which was 88% of the vessels of the normal bone. After 4 weeks, there were markedly increased osteoblastic activities with a total number of 23 vessels, which was 96% of the normal bone. In summary, the revascularization of the membranous inlay bone graft began from the first week after bone graft, and then it gradually increased. After 3 weeks, the revascularization had returned to a nearly normal value compared with the value of the near-by normal mandibular bone.
Animals
;
Blood Vessels
;
Dogs
;
Inlays*
;
Mandible*
;
Osteoblasts
;
Reference Values
;
Transplants*
5.A Case of Patau Syndrome Diagnosed in Early Pregnancy.
Dong Yul SHIN ; Kyung Tai KIM ; Youn Yeung HWANG ; Eun Kyung HONG ; Dong Hun KIM
Korean Journal of Obstetrics and Gynecology 2000;43(2):330-333
Patau syndrome, or Trisomy 13 is one of the most common autosomal aberration associtated with multiple congenital abnormalities. We report a case with trisomy 13 mosacism which was found during an amniocentesis performed due to the age of the mother and abnormal nuchal translucency. The clinical features of fetus included cleft lip and palate, low set ears, polydactily, small ""micro"" penis, and Rocker-bottom feet. After termination of the pregnancy, the fetus was sent for an autopsy. The autopsy report was compatible with the gross findings and pulmonary hypoplasia, microophthalmia, hypoplasia of left ventricle of heart were found.
Amniocentesis
;
Autopsy
;
Cleft Lip
;
Congenital Abnormalities
;
Ear
;
Fetus
;
Foot
;
Heart
;
Heart Ventricles
;
Humans
;
Male
;
Mothers
;
Nuchal Translucency Measurement
;
Palate
;
Penis
;
Pregnancy*
;
Trisomy
6.A Clinical Study of Interrupted Aortic Arch.
Myoung Dong SHIN ; Tae Hun KANG ; Hyoung Doo LEE ; Si Chan SUNG
Journal of the Korean Pediatric Society 1995;38(10):1349-1355
No abstract available.
Aorta, Thoracic*
7.Evaluation of aniline blue dye method for rapid identification of candida albicans.
Kap Jun YOON ; Won Keun SONG ; In Ho JANG ; Dong Hun SHIN
Korean Journal of Clinical Pathology 1993;13(2):271-274
No abstract available.
Candida albicans*
;
Candida*
8.A Case of Chronic Gonorrheal Orbital Cellulitis.
Wan Hun KOO ; Sang Shin KIM ; Dong Jae LEE
Journal of the Korean Ophthalmological Society 1977;18(4):405-407
Authors have experienced a case of long standing chronic gonorrheal orbital cellulitis in a 50 years old Korean male. Surgical evacuation of pus discharges and microscopcially confirmed the gram negative intncellular and extracellular gonococcus. A brief review of the related literatures is present.
Humans
;
Male
;
Middle Aged
;
Neisseria gonorrhoeae
;
Orbit*
;
Orbital Cellulitis*
;
Suppuration
9.A Clinical Analysis of Colorectal Cancer in Young and Elderly Patients.
Hyeong Rok KIM ; Young Jin KIM ; Jung Hun LEE ; Dong Yi KIM ; Shin Kon KIM
Journal of the Korean Society of Coloproctology 1998;14(2):199-208
Colorectal carcinoma in patients under 40 years and over 70 years of age is unusual but not rare. The prognosis of these two groups, compared with remainder of patients, is thought to be unfavorable. From Jan. 1981 to Dec. 1997, 541 patients with primary colorectal cancer who were treated by surgical resection were analyzed retrospectively. They were divided into three age groups according to the age at admission, i.e. under 40 years, over 70 years and between 40 and 69 years(control group). Among three age groups, sex ratio, tumor characteristics(size, location , depth of invasion, lymph node metastasis, liver metastasis, peritoneal metastasis, histopathologic classification, stage, DNA ploidy pattern), serum CEA level and survival were compared and analyzed. The results were as follows: 1) In the young patient group(52 cases), female predominence, large tumor size, high proportion of mucinous adenocarcinoma in histopathologic classification, more frequent metastasis to regional lymph node, frequent peritoneal metastasis and high incidence in tumor location at transverse colon were noted(p<0.05). 2) In the elderly group(69 cases), deep invasion of tumor(T4) was noted (p<0.05). In addition, among them, concomittent diseases were presented in 25 patients(36%). They were diabetes(8), cardiac arrhythmia(4), old myocardial infarction(2), liver cirrhosis(5), COPD(3), previous cancer(3). 3) The 5-year survival rates of the young patient group and that of elderly patient group were lower than that of the other(p<0.01). 4) There was no significant differences in liver metastasis, tumor stage, DNA ploidy pattern, serum CEA level among three age groups.
Adenocarcinoma, Mucinous
;
Aged*
;
Classification
;
Colon, Transverse
;
Colorectal Neoplasms*
;
DNA
;
Female
;
Humans
;
Incidence
;
Liver
;
Lymph Nodes
;
Neoplasm Metastasis
;
Ploidies
;
Prognosis
;
Retrospective Studies
;
Sex Ratio
;
Survival Rate
10.A clinical study on ludwig's angina.
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1998;24(1):68-74
This is a retrospective study on the Ludwig's angina patients treated in Dept of Oral and Maxillofacial Surgery of Pusan National University Hospital for the period of Jan. 1985 to March 1996. The used materials of this study were 30 in total, including 18 male patients, 12 female patients. The author analyzed the distribution and incidence of sex, age, etiologic factor, pus culture, involved systemic disease, treatment methods, mortality rate. The results were as follows; 1. The incidences was higher in sixth decades(26.7%) and prevalent in male. 2. The most cause was odontogenic(83.3%) and in 15 cases(50%), the symptom aggravated after dental treatment. 3. The causative organism isolated from pus culture were Streptococci (40.7%), Staphylococci(22.2%), Bacteroid(14.8%), Candida(11.1%), Pseudomonas(3.7%), Pneumococci(3.7%), Salmonella(3.7%). 4. The patients with systemic disease were 66.7%, involved disease were DM(25%), malnutrition(22.7%), rheumatoid arthritis(11.4%), pulmonary disease(11.4%), hypertension(11.4%). 5. In all patients, surgical I&D was done, and 5 cases(16.7%) required tracheostomy. 6. In all patients, we used combination antibiotics, and the most commonly used antibiotics in the treatment were combination of Penicillin, Cephalosporin and Aminiglycoside(46.7%), and combination of Cephalosporin, Aminiglycoside and Metronidazole(30%). 7. The mortality rate was 6.7%.
Anti-Bacterial Agents
;
Busan
;
Female
;
Humans
;
Incidence
;
Ludwig's Angina*
;
Male
;
Mortality
;
Penicillins
;
Retrospective Studies
;
Suppuration
;
Surgery, Oral
;
Tracheostomy