2.A Case of Malignant Mixed Mullerian Tumor of Uterus.
Sang Wook BAI ; See Yong KIM ; Yoon Ho LEE ; Dong Hoon WHANG
Korean Journal of Gynecologic Oncology and Colposcopy 1993;4(4):118-122
A Malignant mixed miillerian tumor of uterus is rare and highly malignant containing epithelial and mesenchymal components. A case of mixed germ cell tumor was exprienced and presented with a brief review of concerned literature.
Neoplasms, Germ Cell and Embryonal
;
Uterus*
3.Effects of applying antioxidants on bond strength of bleached bovine dentin.
Hyo Jin WHANG ; Dong Hoon SHIN
Restorative Dentistry & Endodontics 2015;40(1):37-43
OBJECTIVES: Some antioxidants are believed to restore dentin bond strength after dental bleaching. This study was done to evaluate the influence of antioxidants on the bond strength of bleached bovine dentin. MATERIALS AND METHODS: Thirty incisors were randomly assigned to 10 groups (two unbleached control and eight bleached groups: immediate bonding IB, 4 wk delayed bonding DB, 10% sodium ascorbate treated SA, 10% alpha-tocopherol treated TP groups). Teeth in half of groups were subjected to thermal stress, whereas the remaining groups were not. Resin-dentin rods with a cross-sectional area of 2.25 mm2 were obtained and microtensile bond strength was determined at a crosshead speed of 1 mm/min. Fifteen specimens were prepared for SEM to compare the surface characteristics of each group. The change in dentin bond strength from thermal stress and antioxidant treatment was evaluated using two-way analysis of variance (ANOVA) and Sheffe's post hoc test at a significance level of 95%. RESULTS: The control group exhibited the highest bond strength values, whereas IB group showed the lowest value before and after thermocycling. The DB group recovered its bond strength similar to that of the control group. The SA and TP groups exhibited similar bond strength values with those of the control and DB groups before thermocycling. However, The TP group did not maintain bond strength with thermal stress, whereas the SA group did. CONCLUSIONS: Applying a 10% sodium ascorbate solution rather than 10% alpha-tocopherol solution for 60 sec is recommended to maintain dentin bond strength when restoring non-vitally bleached teeth.
alpha-Tocopherol
;
Antioxidants*
;
Ascorbic Acid
;
Dentin*
;
Incisor
;
Tooth
;
Tooth Bleaching
4.Two Cases of Squamous Cell Carcinoma of the Bulbar Conjunctiva.
Dong Min KIM ; Sang Hoon RHA ; Seon Ki WHANG
Journal of the Korean Ophthalmological Society 1989;30(5):799-803
Squamous cell carcinoma of the conjunctiva is a rare disease and usually arises at the limbus and spreads to the cornea, adjacent bulbar conjunctiva and sclera. We experienced two cases of squamous cell carcinoma of the cornea and bulbar conjunctiva. One patient was a 36-year old male with progressive loss of visual acuity and discomfort in the nasal side of the left eyeball for about 7 months. The other patient was a 67-year old male with excessive tearing, recurrent conjunctival injection and elevated mass on inferonasal side of the limbus of the left eye. Excisional biopsy was carried out and histopathologic examination revealed bulbar squamous cell carcinoma in both patients.
Adult
;
Aged
;
Biopsy
;
Carcinoma, Squamous Cell*
;
Conjunctiva*
;
Cornea
;
Humans
;
Male
;
Rare Diseases
;
Sclera
;
Visual Acuity
5.A Case of Early-Onset Childhood Sarcoidosis.
Sung Won WHANG ; Dong Soo KIM ; Kwang Hoon LEE
Korean Journal of Dermatology 2000;38(12):1696-1698
Early-onset childhood sarcoidosis is a unique form of the disease characterized by the triad of rash, uveitis, and arthritis in patients presenting before age 4 years. We report a case of early onset childhood sarcoidosis in a 4-year-old girl. She presented with fever, right ankle joint swelling, multiple skin lesions on whole body and was diagnosed as juvenile rheumatoid arthritis in padiatric department. She was transferred to dermatologic department for skin evaluation, histological investigation revealed well-circumscribed, non-caseating naked granuloma with epitheloid cells, histiocytes, lymphocytes on the upper dermis. Laboratory evaluation, chest X-ray, and ophthalmologic evaluation are all within normal limit. She is treated with systemic steroid, methotrexate, non-steroidal anti-inflammatory drugs and follow up evaluation will be planned for possible eye involvement.
Ankle Joint
;
Arthritis
;
Arthritis, Juvenile
;
Child, Preschool
;
Dermis
;
Exanthema
;
Female
;
Fever
;
Granuloma
;
Histiocytes
;
Humans
;
Lymphocytes
;
Methotrexate
;
Sarcoidosis*
;
Skin
;
Thorax
;
Uveitis
6.Clinical Results of Selective Thoracic Fusion by Segmental Pedicle Screws in King type II Adolescent Idiopathic Scoliosis ( AIS ).
Se Il SUK ; Jin Hyok KIM ; Won Jung KIM ; Dong Soo KIM ; Sang Min LEE ; Hoon WHANG
The Journal of the Korean Orthopaedic Association 1998;33(4):1140-1147
STUDY DESIGN: This study analyzes the results of selective thoracic fusion by segmental pedicle screw fixation in King type II adolescent idiopathic scoliosis(AIS). OBJECTIVES: To verify the efficacy of selective thoracic fusion by segmental pedicle screw fixation in King type II adolescent idiopathic scoliosis. SUMMARY OF BACKGROUND DATA: Decompensations following selective thoracic fusion in King type II adolescent idipathic scoliosis have been attributed to relative inability of the lumbar curves to accommodate correction of the thoracic curves. However, with segmental pedicle screw fixation, selective thoracic fusions yielded satisfactory results in most of the patients regardless of the lumbar curve characteristics. MATERIALS AND METHODS: Eighty patients subjected to selective thoracic fusion by segmental pedicle screw fixation were analyzed after a minimum follow-up of 2 years for deformity correction and spinal balance. Deformity correction was performed by derotation of rod contoured to the normal sagittal curve without additional compression or distraction. RESULTS: Mean preoperative thoracic curve of 53.3 was corrected to 20.3 showing a correction of 63.2%. The mean preoperative lumbar curve was 34.4 with a flexibility of 97.2% and mean lumboapical distance(LAD)of 18.0mm, L4 tilt of 8.0, and lumbar apical rotation (LAR) of 10.9. It was corrected to 16.5 showing a correction of 55.5%. All the patients were balanced clinically and radiologically. CONCLUSIONS: Selective thoracic fusion with segmental pedicle screw fixation and rod rotation offers a satisfactory correction of the deformity and maintenance of spinal balance in King type g AIS regardless of lumbar curve magnitude, LAD, L4 tilt or LAR.
Adolescent*
;
Congenital Abnormalities
;
Follow-Up Studies
;
Humans
;
Pliability
;
Scoliosis*
7.Changes in Vertebral Rotation Following Segmental Pedicle Screw Instrumentation and Rod Derotation in Idiopathic Thoracic Scoliosis : Part I - CT Evaluation.
Won Jung KIM ; Se Il SUK ; Chil Soo KWON ; Jin Hyok KIM ; Dong Soo KIM ; Sang Min LEE ; Hoon WHANG
The Journal of the Korean Orthopaedic Association 1998;33(4):1164-1169
The employment of segmental pedicle screw instrumentation has greatly enhanced the correction of scoliotic deformity. However there is still much controversy on the ability of the system to correct the rotational deformity. This prospective study with 12 idiopathic throacic scoliosis patients subjected to segmental pedicle screw instrumentation was performed to determine the effect of the system on the rotational deformity of idiopathic throacic scoliosis. In addition to the standing films to measure the magnitude of scoliotic curvatures, preand postoperative CT were utilized for the measurement and comparison of angle of rotation relative to the sagittal plane(RAsag.), relative rotation with reference to the upper and lower end vertebrae(RAend), relative rotation with reference to the sacrum(RAsac.), frontal translation(TF) and sagittal translation(TS) for the apical vertebrae. Despite the high correction rate obtained in the frontal plane(average 71.1%) and normalization of sagittal contour, the rotational corrections were statistically insignificant in all parameters and showed no significant correlation to the correction of the curvatures nor horizontal plane displacement as represented by the frontal and sagittal displacement. In conclusions, the segmental pedicle screw instrumentation with rod derotation does not produce significant derotation by itself.
Congenital Abnormalities
;
Employment
;
Humans
;
Prospective Studies
;
Scoliosis*
;
Spine
8.Imatinib Mesylate (Gleevec(TM))-induced Lichenoid Drug Eruption Improved by Tentative Dose-reduction and Topical Steroid.
Jung Hoon YANG ; Jung Woong SHIN ; Hyung Dong KIM ; Young Lip PARK ; Sung Yul LEE ; Kyu Uang WHANG
Korean Journal of Dermatology 2011;49(2):155-158
Imatinib mesylate (Gleevec(TM)) is an oral anticancer drug. It works as a selective and competitive inhibitor of tyrosine kinases such as bcr-abl protein, c-kit, and platelet-derived growth factor receptors (PDGFR). Gleevec(TM) is a first-line therapeutic agent for chronic myelogenous leukemia (CML) and gastrointestinal stromal tumors, but causes various adverse cutaneous reactions. We herein report on a case of lichenoid drug eruption induced by Gleevec(TM) in a patient with a malignant gastrointestinal stromal tumor.
Benzamides
;
Drug Eruptions
;
Gastrointestinal Stromal Tumors
;
Humans
;
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
;
Mesylates
;
Phosphotransferases
;
Piperazines
;
Pyrimidines
;
Receptors, Platelet-Derived Growth Factor
;
Tyrosine
;
Imatinib Mesylate
9.Right Hepatic Lobectomy for Adult Living Donor Liver Transplantation Safety, anatomical points, and technical points.
Young Joo LEE ; Seung Gyu LEE ; Kwang Min PARK ; Shin WHANG ; Ki Hoon KIM ; Dong Rak CHOI ; Pyung Chul MIN
Journal of the Korean Surgical Society 1999;57(4):558-565
BACKGROUND: Living related liver transplantation (LRLT) has gained acceptance as treatment modality for children with end-stage liver disease. The left lobe used in LRLT doesn't provide adequate parenchymal mass for its application to adults. We have used right lobe for LRLT in adults. Some criticism has been aroused becuase of the potential significant risk to the donors. METHODS: We analyzed the surgical risk and the stress to 20 donors in a right lobectomy for LRLT. We also analyzed anatomical points for safe harvest, and we describe techincal points based on anatomical variations. RESULTS: There were no deaths, and 6 major complications (3 bleeding, 1 perihepatic fluid collection, 1 pleural effusion, and 1 bile peritonitis after removal of the T-tube) occurred in 6 patients. Liver function was normalized within 2 weeks. There were anatomical variations in the hepatic vein, the portal vein, and the bile duct, especially the right inferior hepatic vein (55%), trifurcation of the portal vein (10%), low inserion of the right posterior bile duct into the common hepatic duct (10%), and separate insertion of the right anterior bile duct and right posterior bile duct into the hepatic duct (10%). We made a vena cava patch for the right inferior hepatic vein. In cases of the low insertion of the right posterior hepatic duct into the common hepatic duct, the cholecystectomy should be done carefully so as not to injure the right posterior hepatic duct. We ligated and divided the right posterior bile duct before dissection of the hepatic artery and the portal vein. In cases of trifurcation of the portal vein, closure of the left portal vein should be done to prevent the narrowing of the left portal vein lumen. CONCLUSIONS: Our results suggest that a right lobectomy for LRLT is safe for donors. However, anatomical variations in the bile duct, the hepatic vein, and the portal vein should be kept in mind to ensure a safe and successful operation.
Adult*
;
Bile
;
Bile Ducts
;
Child
;
Cholecystectomy
;
Hemorrhage
;
Hepatic Artery
;
Hepatic Duct, Common
;
Hepatic Veins
;
Humans
;
Liver Diseases
;
Liver Transplantation*
;
Liver*
;
Living Donors*
;
Peritonitis
;
Pleural Effusion
;
Portal Vein
;
Tissue Donors
10.A Case of Percutaneous Transluminal Coronary Angioplasty with Stent in a Patient of Acute Myocardial Infarction with Situs Inversus Totalis.
Kyung Wha WHANG ; Tae Yong KIM ; Joon Young KIM ; Yu Jeong CHOI ; Hong Youp CHOI ; Jane C OH ; Sang Wook LIM ; Dong Hoon CHA
Korean Circulation Journal 1999;29(9):985-988
Situs inversus totalis with dextrocardia is a rare congenital anomaly and its incidence is approximately 1: 6,000-35,000 in general population. Such patients usually have structurally normal hearts and are expected to have normal life span. Coronary angioplasty in such patients have previously been reported, but reported cases in literature are scanty. This report describes our experience of successful percutaneous transluminal coronary angioplasty with stent in acute myocardial infarction patient with situs inversus totalis and dextrocardia who exhibited total occlusion of the mid left anterior descending coronary artery.
Angioplasty
;
Angioplasty, Balloon, Coronary*
;
Coronary Vessels
;
Dextrocardia
;
Heart
;
Humans
;
Incidence
;
Myocardial Infarction*
;
Situs Inversus*
;
Stents*