2.A Case of Malignant Mixed Mullerian Tumor of Uterus.
Sang Wook BAI ; See Yong KIM ; Yoon Ho LEE ; Dong Hoon WHANG
Korean Journal of Gynecologic Oncology and Colposcopy 1993;4(4):118-122
A Malignant mixed miillerian tumor of uterus is rare and highly malignant containing epithelial and mesenchymal components. A case of mixed germ cell tumor was exprienced and presented with a brief review of concerned literature.
Neoplasms, Germ Cell and Embryonal
;
Uterus*
3.Effects of applying antioxidants on bond strength of bleached bovine dentin.
Hyo Jin WHANG ; Dong Hoon SHIN
Restorative Dentistry & Endodontics 2015;40(1):37-43
OBJECTIVES: Some antioxidants are believed to restore dentin bond strength after dental bleaching. This study was done to evaluate the influence of antioxidants on the bond strength of bleached bovine dentin. MATERIALS AND METHODS: Thirty incisors were randomly assigned to 10 groups (two unbleached control and eight bleached groups: immediate bonding IB, 4 wk delayed bonding DB, 10% sodium ascorbate treated SA, 10% alpha-tocopherol treated TP groups). Teeth in half of groups were subjected to thermal stress, whereas the remaining groups were not. Resin-dentin rods with a cross-sectional area of 2.25 mm2 were obtained and microtensile bond strength was determined at a crosshead speed of 1 mm/min. Fifteen specimens were prepared for SEM to compare the surface characteristics of each group. The change in dentin bond strength from thermal stress and antioxidant treatment was evaluated using two-way analysis of variance (ANOVA) and Sheffe's post hoc test at a significance level of 95%. RESULTS: The control group exhibited the highest bond strength values, whereas IB group showed the lowest value before and after thermocycling. The DB group recovered its bond strength similar to that of the control group. The SA and TP groups exhibited similar bond strength values with those of the control and DB groups before thermocycling. However, The TP group did not maintain bond strength with thermal stress, whereas the SA group did. CONCLUSIONS: Applying a 10% sodium ascorbate solution rather than 10% alpha-tocopherol solution for 60 sec is recommended to maintain dentin bond strength when restoring non-vitally bleached teeth.
alpha-Tocopherol
;
Antioxidants*
;
Ascorbic Acid
;
Dentin*
;
Incisor
;
Tooth
;
Tooth Bleaching
4.Two Cases of Squamous Cell Carcinoma of the Bulbar Conjunctiva.
Dong Min KIM ; Sang Hoon RHA ; Seon Ki WHANG
Journal of the Korean Ophthalmological Society 1989;30(5):799-803
Squamous cell carcinoma of the conjunctiva is a rare disease and usually arises at the limbus and spreads to the cornea, adjacent bulbar conjunctiva and sclera. We experienced two cases of squamous cell carcinoma of the cornea and bulbar conjunctiva. One patient was a 36-year old male with progressive loss of visual acuity and discomfort in the nasal side of the left eyeball for about 7 months. The other patient was a 67-year old male with excessive tearing, recurrent conjunctival injection and elevated mass on inferonasal side of the limbus of the left eye. Excisional biopsy was carried out and histopathologic examination revealed bulbar squamous cell carcinoma in both patients.
Adult
;
Aged
;
Biopsy
;
Carcinoma, Squamous Cell*
;
Conjunctiva*
;
Cornea
;
Humans
;
Male
;
Rare Diseases
;
Sclera
;
Visual Acuity
5.A Case of Early-Onset Childhood Sarcoidosis.
Sung Won WHANG ; Dong Soo KIM ; Kwang Hoon LEE
Korean Journal of Dermatology 2000;38(12):1696-1698
Early-onset childhood sarcoidosis is a unique form of the disease characterized by the triad of rash, uveitis, and arthritis in patients presenting before age 4 years. We report a case of early onset childhood sarcoidosis in a 4-year-old girl. She presented with fever, right ankle joint swelling, multiple skin lesions on whole body and was diagnosed as juvenile rheumatoid arthritis in padiatric department. She was transferred to dermatologic department for skin evaluation, histological investigation revealed well-circumscribed, non-caseating naked granuloma with epitheloid cells, histiocytes, lymphocytes on the upper dermis. Laboratory evaluation, chest X-ray, and ophthalmologic evaluation are all within normal limit. She is treated with systemic steroid, methotrexate, non-steroidal anti-inflammatory drugs and follow up evaluation will be planned for possible eye involvement.
Ankle Joint
;
Arthritis
;
Arthritis, Juvenile
;
Child, Preschool
;
Dermis
;
Exanthema
;
Female
;
Fever
;
Granuloma
;
Histiocytes
;
Humans
;
Lymphocytes
;
Methotrexate
;
Sarcoidosis*
;
Skin
;
Thorax
;
Uveitis
6.Clinical Results of Selective Thoracic Fusion by Segmental Pedicle Screws in King type II Adolescent Idiopathic Scoliosis ( AIS ).
Se Il SUK ; Jin Hyok KIM ; Won Jung KIM ; Dong Soo KIM ; Sang Min LEE ; Hoon WHANG
The Journal of the Korean Orthopaedic Association 1998;33(4):1140-1147
STUDY DESIGN: This study analyzes the results of selective thoracic fusion by segmental pedicle screw fixation in King type II adolescent idiopathic scoliosis(AIS). OBJECTIVES: To verify the efficacy of selective thoracic fusion by segmental pedicle screw fixation in King type II adolescent idiopathic scoliosis. SUMMARY OF BACKGROUND DATA: Decompensations following selective thoracic fusion in King type II adolescent idipathic scoliosis have been attributed to relative inability of the lumbar curves to accommodate correction of the thoracic curves. However, with segmental pedicle screw fixation, selective thoracic fusions yielded satisfactory results in most of the patients regardless of the lumbar curve characteristics. MATERIALS AND METHODS: Eighty patients subjected to selective thoracic fusion by segmental pedicle screw fixation were analyzed after a minimum follow-up of 2 years for deformity correction and spinal balance. Deformity correction was performed by derotation of rod contoured to the normal sagittal curve without additional compression or distraction. RESULTS: Mean preoperative thoracic curve of 53.3 was corrected to 20.3 showing a correction of 63.2%. The mean preoperative lumbar curve was 34.4 with a flexibility of 97.2% and mean lumboapical distance(LAD)of 18.0mm, L4 tilt of 8.0, and lumbar apical rotation (LAR) of 10.9. It was corrected to 16.5 showing a correction of 55.5%. All the patients were balanced clinically and radiologically. CONCLUSIONS: Selective thoracic fusion with segmental pedicle screw fixation and rod rotation offers a satisfactory correction of the deformity and maintenance of spinal balance in King type g AIS regardless of lumbar curve magnitude, LAD, L4 tilt or LAR.
Adolescent*
;
Congenital Abnormalities
;
Follow-Up Studies
;
Humans
;
Pliability
;
Scoliosis*
7.Changes in Vertebral Rotation Following Segmental Pedicle Screw Instrumentation and Rod Derotation in Idiopathic Thoracic Scoliosis : Part I - CT Evaluation.
Won Jung KIM ; Se Il SUK ; Chil Soo KWON ; Jin Hyok KIM ; Dong Soo KIM ; Sang Min LEE ; Hoon WHANG
The Journal of the Korean Orthopaedic Association 1998;33(4):1164-1169
The employment of segmental pedicle screw instrumentation has greatly enhanced the correction of scoliotic deformity. However there is still much controversy on the ability of the system to correct the rotational deformity. This prospective study with 12 idiopathic throacic scoliosis patients subjected to segmental pedicle screw instrumentation was performed to determine the effect of the system on the rotational deformity of idiopathic throacic scoliosis. In addition to the standing films to measure the magnitude of scoliotic curvatures, preand postoperative CT were utilized for the measurement and comparison of angle of rotation relative to the sagittal plane(RAsag.), relative rotation with reference to the upper and lower end vertebrae(RAend), relative rotation with reference to the sacrum(RAsac.), frontal translation(TF) and sagittal translation(TS) for the apical vertebrae. Despite the high correction rate obtained in the frontal plane(average 71.1%) and normalization of sagittal contour, the rotational corrections were statistically insignificant in all parameters and showed no significant correlation to the correction of the curvatures nor horizontal plane displacement as represented by the frontal and sagittal displacement. In conclusions, the segmental pedicle screw instrumentation with rod derotation does not produce significant derotation by itself.
Congenital Abnormalities
;
Employment
;
Humans
;
Prospective Studies
;
Scoliosis*
;
Spine
8.Flushing in a Young Woman: Skin Manifestation of Carcinoid Syndrome.
Ji Hoon SIM ; Gun Hong LEE ; Hyung Dong KIM ; Sung Yul LEE ; Young Lip PARK ; Kyu Uang WHANG
Korean Journal of Dermatology 2011;49(11):1006-1009
Carcinoid tumors are derived from enterochromaffin cells that are capable of producing a wide range of neuroendocrine mediators including serotonin or 5-hydroxytryptamine. Carcinoid syndrome occurs when mediators produced by the tumor and normally metabolized by the liver escape into the systemic circulation. The syndrome classically involves the gastrointestinal tract, respiratory system, cardiovascular system and the skin. Flushing is almost universal in the syndrome. A 23-year-old woman came to our hospital presenting with flushing on face and trunk. The patient had experienced flushing for 2 years and it was aggravated by emotional change, stress, exercise, and eating spicy food. The patient also had abdominal pain, diarrhea, weight loss and hepatomegaly. Urinary 5-hydroxyindoleacetic acid was elevated (81.5 mg/day). Abdominal computed tomography scans showed multiple hepatic masses diagnosed as a carcinoid tumor by computed tomography-guided needle biopsy. Physicians should consider carcinoid syndrome when patients present with flushing and systemic symptoms.
Abdominal Pain
;
Biopsy, Needle
;
Carcinoid Tumor
;
Cardiovascular System
;
Collodion
;
Diarrhea
;
Eating
;
Enterochromaffin Cells
;
Female
;
Flushing
;
Gastrointestinal Tract
;
Hepatomegaly
;
Humans
;
Liver
;
Porphyrins
;
Respiratory System
;
Serotonin
;
Skin
;
Skin Manifestations
;
United Nations
;
Weight Loss
;
Young Adult
9.A Case of Congenital Pericardial Defect Diagnosed by Computed Tomography.
Hong Youp CHOI ; Sang Wook LIM ; Joon Young KIM ; Byung Wook NA ; Kyung Wha WHANG ; Eun Mi JEONG ; Tae Yong KIM ; Dong Hoon CHA ; Jeung Sook KIM
Korean Circulation Journal 2000;30(10):1281-1284
Pericardial defect is a rare congenital cardiac disorder. Most patients were asymptomatic but some patients with partial pericardial defect occasionally complain acute symptoms such as angina, syncope, rarely sudden cardiac death. So, differential diagnosis with other ischemic or structural heart disease is crucial in the management of such patients. But there is no consistently successful diagnostic method. In the past, artificial diagnostic pneumothorax was used to document the absence of pericardium. However, it is not easily accepted due to excess morbidity and failure rate. Recently, echocardiography and more often, computed tomography, magnetic resonance imaging are used to confirm the diagnosis. We experienced a 52 years old male patient with atypical chest pain, who was diagnosed as complete left pericardial defect with computed tomography.
Chest Pain
;
Death, Sudden, Cardiac
;
Diagnosis
;
Diagnosis, Differential
;
Echocardiography
;
Heart Diseases
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Middle Aged
;
Pericardium
;
Pneumothorax
;
Syncope
10.Cutaneous Metastasis of Lung Angiosarcoma to the Scalp.
Ji Hoon SIM ; Jung Woong SHIN ; Hyung Dong KIM ; Young Lip PARK ; Jong Suk LEE ; Kyu Uang WHANG
Korean Journal of Dermatology 2011;49(6):520-523
Angiosarcoma is a rare malignant tumor of an endothelial cell derivation and it accounts for less than 2% of all sarcomas. It is a highly aggressive neoplasm with a poor prognosis and most patients die within a short period after presentation. Although angiosarcoma may occur in any location on the body, it rarely arises from major vessels, but has a decided predilection for the skin and superficial soft tissue. A 39-year-old man was referred to our department with an asymptomatic, firm, ulcerative nodule on his scalp that was noticed almost 2 months previously. He had been diagnosed with lung angiosarcoma 9 month earlier. Histopathologically, the skin specimen showed angiosarcoma. The histological findings of the metastatic skin cancer are usually the same as that of the primary cancer. Metastatic cutaneous angiosarcoma is uncommon. Based on these clinical and histopathological findings, our case seems to be skin metastasis at the scalp from the lung angiosarcoma.
Adult
;
Endothelial Cells
;
Hemangiosarcoma
;
Humans
;
Lung
;
Neoplasm Metastasis
;
Prognosis
;
Sarcoma
;
Scalp
;
Skin
;
Skin Neoplasms
;
Ulcer