We aimed to evaluate the long term trantment of enalapril on the vascular response in the isolated aorta, and in anesthetized or pithed spontaneously hypertensive rats(SHR). In the isolated aorta, the increase in tension provoked by addition of KC1 16.7mM was attenuated by enalapril treatment(3mg/kg/day for 6 weeks), whereas the increment by addition of NE 0.1uM tension was not influenced. The frequency-dependent vasoconstricution induced by electrical field stimulation of aorta was also attenuated by enalapril treatment. In pithed SHR, the frequency-related hypertension provoked by electrical stimulation(10sec, 1ms with 40V) of sympathetic pregnglionic nerve was also attenuated by enalapril treatment. Neither dose-related vasorelaxation by acetylcholine addition in the aorta nor decrease of DBP by intravenously(i.v.)-injected aetylcholine was altered by enalapril treatment. However, beta2-agonist, salbutamol-induced vasorelaxation in enalapril-treated group, was more remarkable than that in control group. The hypotension by i.v.-but not by intracerebroventricularly-injected salbutamol strengthened by enalapril treatment. These results suggest that the suppression of development of hypertension by enalapril treatment may result from the reduction of adrenergic neurotransmission and activity to voltage dependent calcium channel by acting on vascular smooth muscle itself.
Acetylcholine ; Albuterol ; Aorta ; Blood Pressure* ; Calcium Channels ; Enalapril* ; Hypertension ; Hypotension ; Muscle, Smooth, Vascular ; Rats, Inbred SHR* ; Synaptic Transmission ; Vasodilation

Necrotizing fasciitis, an uncommon, often fulminant bacterial infection, rarely originates in the chest wall. Although it can occur in any region of the body, the abdominal wall, perineum, and extremities are the most common sites of infection. It is characterized by wide spread fascial necrosis with relative sparing of skin and underlying muscle. Diagnosis is often extremely difficult and relies on a high index of suspicion. Prompt surgical intervention is essential. We experienced a patient with idiopathic necrotizing fasciitis in the chest wall and reported with brief review of literature.
Abdominal Wall ; Bacterial Infections ; Diagnosis ; Extremities ; Fasciitis, Necrotizing* ; Humans ; Necrosis ; Perineum ; Skin ; Thoracic Wall* ; Thorax*

BACKGROUND: Bullectomy through a transaxillary minithoracotomy have been widely used in the treatment of primary spontaneous pneumothorax. MATERIAL AND METHOD: From September 1997 to September 1998, 22 consecutive cases of those who underwent transaxillary mini thoracotomy with Finochieto rib spreader(group F) and 24 consecutive cases with Naruke thoraco-opener(group N) at Taegu Fatima Hospital were reviewed retrospectively to compare the clinical results of transaxillary minithoracotomy with different rib spreaders in the opera tive treatments of primary spontaneous pneumothorax. RESULT: There were no significant differences in operative time, hospital stay, postoperative hospital stay, the duration of the indwelling chest tube, and the number of postoperative recurrences and complications in the two group. CONCLUSION This technique may be useful in the operative treatments of primary spontaneous pneumothorax.
Chest Tubes ; Daegu ; Length of Stay ; Operative Time ; Pneumothorax* ; Recurrence ; Retrospective Studies ; Ribs ; Thoracotomy

No abstract available.
Hospitals, General* ; Humans ; Outpatients*

BACKGROUND: To evaluate the efficacy of cellulose mesh with fibrin glue to decrease recurrence rate after bullectomy for a treatment of primary spontaneous pneumothorax. MATERIAL AND METHOD: 222 patients underwent a bullectomy for primary spontaneous pneumothorax in our institute between April. 1996, and June, 2000. Patients were divided into four groups by period and operation method. Group 1(n=25) underwent video-assited thorasic surgery(VATS) and mechanical pleurodesis between 1996 and 1997. Group 2(n=53) underwent axillary thoracotomy and mechanical pleurodesis between the same period. Group 3(n=110) undewent VATS and mechanical pleurodesis between 1998 and April, 2000. Group 4(n=34) underwent VATS and reinforcement with absorbable cellulose mesh and fibrin glue between 1998 and June, 2000. The data of recurrence rate, duration of air leakage, and duration of chest tube drainage evaluated by each group were compared and analysed using general linear model procedure. RESULT: There were 203 men and 19 women. Mean age was 23.2+9.6 years. Recurrent rate in group 1 was 25%, 3.8% in group 2 and 4.5% in group 3. Threre was no recurrence of pneumothorax in group 4. All recurrent cases after bullectomy were developed at the period of surgeon' s experience of bullectomy if it was less than 2 years. Chest tube indwelling period in group 4 was shorter compared to that of group 1,group 2(p<0.0006) and group 3(p<0.0001). There was no postoperative air- leakage in group 4. Recurrence rate was higher in minimal and moderate size pneumothorax than that in massive pneumothorax. In the 12 recurred cases, nine cases had blebs near the suture line. CONCLUSION: The covering of the suture area with an bsorbable cellulose mesh and the application of the fibrin glue on the mesh in wedge resection of blebs are effective and shorter tube indwelling period was resulted. There were no postoperative air leakage through chest tube after this additional procedure and no recurrence in short term follow-up period. Recurrence rate was higher in small size pneumothorax than that in large sizepneumothorax. Recurrence rate was also influenced by the experience of surgeon.
Blister ; Cellulose ; Cellulose, Oxidized* ; Chest Tubes ; Drainage ; Female ; Fibrin Tissue Adhesive* ; Fibrin* ; Follow-Up Studies ; Humans ; Linear Models ; Male ; Pleurodesis ; Pneumothorax* ; Recurrence ; Sutures* ; Thoracic Surgery, Video-Assisted ; Thoracotomy

BACKGROUND: Video-assisted thoracic sympathicotomy plays an important role as an effective method for the treatment of axillary hyperhidrosis. People with axillary hyperhidrosis were not satisfied by the occurrence of the high rate of disabling compensatory hyperhidrosis and axillary resweating. Therefore, by comparing and assessing the clincal results according to the level and extent of sympathicotomy in axillary hyperhidrosis, we aim to determine which method will result in maximal benefits. MATERIAL AND METHOD: Among 70 patients suffering from axillary hyperhidrosis having undergone thoracoscopic sympathicotomy from January 2001 through December 2003, 57 patients who responded to either telephone interview or questionnaire were included in the current study. The patients were divided into two groups, Group I (n=25): patients having undergone R3, 4, 5 sympathicotomy which consist of blocking the interganglionic neural fiber on the third, fourth, and fifth rib, Group II (n=32): patients having undergone R3,4 sympathicotomy which consist of blocking the interganglionic neural fiber on the third and fourth rib. The study parameters were satisfaction rate and degree of compensatory sweating. RESULT: There was no difference on age and sex, family history, combined hyperhidrosis, and mean follow up month between the two groups. Patients expressing satisfaction were 88.0% in group and 56.3% in groups II with statistically significant difference (p=0.02). Moderate to severe compensatory sweating were 52.0% (embrassing 6 patients, disabling 7 patients) in group I and 62.5% (embrassing 5 patients, disabling 15 patients) in groups II with no significance in the statistical analysis. CONCLUSION: R3, 4, 5 sympathicotomy was an effective means of treating axillary hyperhidrosis because of higher long term satisfaction rate.
Follow-Up Studies ; Humans ; Hyperhidrosis* ; Interviews as Topic ; Quality of Life ; Surveys and Questionnaires ; Ribs ; Sweat ; Sweating

Phthiriasis has been usually known as a sexually-transmitted disease. The majority of these cases are found in the hair of the genital lesion, however, infestation of the eyelashed may occur. Eyeld involvement frequently causes blepharitis or conjunctivitis. The authors found a crab louse, Phthirus pubis and their nits on the eyelashes of 22-year-old female who complained foreign body and itching sensation of her right upper lid. Treatment is accomplished by careful mechanical removal of the louse and nits followed by the epilation and alllication of antibiotic eyedrops. We report a case of Phthiriasis palpebrarum with a review of the literatures.
Blepharitis ; Conjunctivitis ; Eyelashes ; Female ; Foreign Bodies ; Hair ; Hair Removal ; Humans ; Ophthalmic Solutions ; Pediculus ; Phthiraptera ; Phthirus ; Pruritus ; Sensation ; Young Adult

No abstract available.
Mitral Valve Insufficiency*

PURPOSE: This study was undertaken to evaluate the clinical results of pars plana vitrectomy on posterior segment complications in posterior uveitis. METHODS: We reviewed the records of 20 eyes of 19 uveitis patients who were followed up for 6 months or more after vitrectomy. RESULTS: The mean follow-up period was 20 months. Final visual acuity improved in 10 eyes (50%), was maintained in 6 (30%), and decreased in 4 (20%). The mean improvement of vision was 1.6 lines (p=0.019). Detached retina was reattached in 8 (80%) among the 10 eyes with primary surgery. Postoperative complications were cataract (7 eyes), macular degeneration (2 eyes), retinal detachment (2 eyes), and recurrence (1 eye). CONCLUSIONS: These results suggest that pars plana vitrectomy may be a safe and effective treatment for posterior segment complications in posterior uveitis, but that early and complete vitrectomy should be considered for a better visual prognosis.
Cataract ; Follow-Up Studies ; Humans ; Macular Degeneration ; Postoperative Complications ; Prognosis ; Recurrence ; Retina ; Retinal Detachment ; Uveitis ; Uveitis, Posterior* ; Visual Acuity ; Vitrectomy*

No abstract available.
Humans