No abstract available.
Humans ; Technetium Tc 99m Disofenin* ; Ultrasonography*

No abstract available.
Humans ; Peritoneal Dialysis* ; Spinal Cord*

PURPOSE: The purpose of this study is to evaluate the use of plain knee films in assessing the position of tibial component after total knee arthroplasty. MATERIALS AND METHODS: Plain radiological antero-posterior(AP) and lateral view of tibia of 51 adults (mean age: fifty-years old) were taken. On AP view, the medial angles between tibia plateau and mechanical, anatomical and proximal anatomical axis of tibia were measured, and then correlation of each angle and the angle between the tibia plateau and anatomical axis were assessed. On lateral view, the posterior angle formed between the medial tibial plateau and anatomical, proximal anatomical axis, anterior and posterior cortex of proximal tibia were measured, and then correlation of each angle and the angle between the medial tibial plateau and anatomical axis were assessed. RESULTS: On tibial AP view, both axes had significant correlation(p<0.05) with the anatomical axis. The anatomical axis of proximal tibia was closest to it. On lateral view, all three axes had significant correlation(p<0.05) with anatomical axis. Among these, the anterior cortex of proximal tibia was closest to it. CONCLUSION: The position of the tibia component and posterior slope after total knee arthroplasty can be measured on plain knee X-rays using anatomical axis and the anterior cortex line of proximal tibia.
Adult ; Arthroplasty ; Axis, Cervical Vertebra* ; Humans ; Knee* ; Tibia

Endothelin (ET)-1 and its receptors (ETA and ETB receptor) are present in the central nervous system. ET exerts biological effects on gliogenesis and glial cell functions. In order to define a possible mechanism of ETA receptor signaling, the distribution of the ETA receptor in developing oligodendrocytes and the effects of ET-1 on the myelination of oligodendrocytes were examined. ETA receptor immunoreactivity was confined to the perivascular elements of the blood vessels during early postnatal development. However later in development, ETA receptor immunoreactivity was no longer observed in the vessels but became localized to the myelinating oligodendrocytes of the primitive corpus callosum of the white matter, apart from the vessels. ET-1 induced myelin basic protein (MBP) in primary oligodendrocyte precursor cell culture though the ETA receptor and was blocked by an ETA receptor antagonist. In addition, ET-1 evoked the release of Ca2+ which is a central regulator of oligodendrocyte differentiation. Our results provide a link between ET-1 and its ETA receptor and myelination during oligodendrocyte differentiation.
Animals ; Brain/pathology ; Calcium/metabolism ; Calcium Signaling ; Cells, Cultured ; Endothelin-1/metabolism/physiology ; Mice ; Mice, Inbred ICR ; Myelin Basic Proteins/genetics/metabolism ; Myelin Sheath/*physiology ; Oligodendroglia/cytology/*metabolism ; Rats ; Rats, Sprague-Dawley ; Receptor, Endothelin A/metabolism/*physiology