2.Outdoor Air Pollution and Pterygium in Korea.
Ki Woong LEE ; Yoon Hyeong CHOI ; Sung Ha HWANG ; Hae Jung PAIK ; Mee Kum KIM ; Won Ryang WEE ; Dong Hyun KIM
Journal of Korean Medical Science 2017;32(1):143-150
We investigated relationships between outdoor air pollution and pterygium in Korean adults. This study includes 23,276 adults in population-based cross-sectional data using the Korea National Health and Nutrition Examination Survey 2008–2011. Pterygium was assessed using slit lamp biomicroscopy. Air pollution data (humidity, particulate matter with aerodynamic diameter less than 10 μm [PM₁₀], ozone [O₃], nitrogen dioxide [NO₂], and sulfur dioxide levels [SO₂]) for 2 years preceding the ocular examinations were acquired. Associations of multiple air pollutants with pterygium or pterygium recurrence after surgery were examined using multivariate logistic models, after adjusting for several covariates. Distributed lag models were additionally used for estimating cumulative effects of air pollution on pterygium. None of air pollution factors was significantly associated with pterygium or pterygium recurrence (each P > 0.05). Distributed lag models also showed that air pollution factors were not associated with pterygium or pterygium recurrence in 0-to-2 year lags (each P > 0.05). However, primary pterygium showed a weak association with PM₁₀ after adjusting for covariates (odds ratio [OR] 1.23; [per 5 μg/m³ PM₁₀ increase]; P = 0.023). Aging, male sex, and greater sun exposure were associated with pterygium, while higher education level and myopia were negatively associated with pterygium (each P ≤ 0.001). Male sex and myopia were negatively associated with pterygium recurrence (each P < 0.05). In conclusion, exposure to higher PM10 levels was associated with primary pterygium, although this study observed no significant association between air pollution and overall pterygium or pterygium recurrence in Korean adults.
Adult
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Aging
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Air Pollutants
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Air Pollution*
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Education
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Humans
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Korea*
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Logistic Models
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Male
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Myopia
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Nitrogen Dioxide
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Nutrition Surveys
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Ozone
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Particulate Matter
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Pterygium*
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Recurrence
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Slit Lamp
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Solar System
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Sulfur Dioxide
3.Annual Report on External Quality Assessment in Immunoserology in Korea (2003).
Young Joo CHA ; So Yong KWON ; Dong Gil KUM ; Sung Won KIM ; Think You KIM ; Jae Ryong KIM ; Hyon Suk KIM ; Myong Hee PARK ; Seong Hoon PARK ; Ae Ja PARK ; Han Chul SON ; Joo Suk YANG ; Kye Sook LEE ; Seok Lae CHAE
Journal of Laboratory Medicine and Quality Assurance 2004;26(1):47-69
The followings are the results for external quality assessment (EQA) in immunoserology for 2003: 1.Evaluation of EQA was done in 2 trials in May and November, about 99% of laboratories participating average 8.2 items. 2.In C-reactive protein (CRP), rheumatoid factor (RF) and anti-streptolysin O (ASO) tests, about 63%, 49% and 44% of the participating laboratories respectively have used quantitative assays. Because the laboratories using quanitiative assays were on the increase annually, commercial control, Liquicheck(TM) Immunology Contol from Bio-Rad Laboratories (Irvine, CA, USA) was used to assure the quality of quantitiavie results in 2003. A few laboratories reproted the outlier results, comparing with the reference ranges presented by the company. 3.Over 92% of participating laboratoreis have used imunoassays including enzyme immunoassay (EIA), microparticle EIA (MEIA), chemiluminescence immunoassay (CIA), immunochromatography assay (ICA) or radioimmunoassay (RIA) for detedting viral antigens or antibodies. Especially for anti-HCV, over 98% of participating laboratoreis have used various kind of imunoassays. Laboratories using ICA increased and about 24% of participating laboratoreis have used ICA for anti-HCV and anti-HIV. However, many laboratories using ICA for detecting anti-HCV reported false negative results, suggesting lower sensitivity of ICA than those of other immunoassays. 4.The criteria of interpretation were considered to be evaluated in Widal test and laboratories using ICA increased in serological tests for syphilis.
Allergy and Immunology
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Antibodies
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Antigens, Viral
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C-Reactive Protein
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Hepatitis B Surface Antigens
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Immunoassay
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Immunochromatography
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Immunoenzyme Techniques
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Korea*
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Luminescence
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Nephelometry and Turbidimetry
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Radioimmunoassay
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Reference Values
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Rheumatoid Factor
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Serologic Tests
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Syphilis
4.Annual Report on External Quality Assessment in Immunoserology in Korea (2004).
Young Joo CHA ; So Yong KWON ; Dong Gil KUM ; Sung Won KIM ; Think You KIM ; Jae Ryong KIM ; Hyon Suk KIM ; Myong Hee PARK ; Seong Hoon PARK ; Ae Ja PARK ; Han Chul SON ; Joo Suk YANG ; Kye Sook LEE ; Seok Lae CHAE
Journal of Laboratory Medicine and Quality Assurance 2005;27(1):37-57
The followings are the results for external quality assessment (EQA) in immunoserology for 2004: 1. Evaluation of EQA was done in 2 trials in May and November, about 99% of laboratories participating average 8.4 items. EQA for anti-HBc test was newly started in 2004. 2. Commercial control, MASR Immunology Control from Medical Analysis Systems (Camarillo, CA, USA) was used to assure the quality of quantitative results of C-reactive protein (CRP), rheumatoid factor (RF) and anti-streptolysin O (ASO) tests in 2004. All the specimens for Immunoserology in EQA were delivered refrigerated for the first time, being received within 48 hours after sending. 3. EQA for detection of HBsAg mutants was tried for the first time, using the recombinant HBsAg mutant (Gly/Arg 145) kindly provided by Abbott Laboratories, USA. 4. The laboratories using immunochromatography assay (ICA) were increased, however, many laboratories using ICA reported falsely negative for the positive specimens. The sensitivity of ICA test kits as well as various factors influencing the ICA results should be evaluated. 5. Standardization of methods including calibrators for quantitative results should be required for the harmonization of results.
Allergy and Immunology
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C-Reactive Protein
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Hepatitis B Surface Antigens
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Immunochromatography
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Korea*
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Nephelometry and Turbidimetry
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Rheumatoid Factor
5.Annual Report on External Quality Assessment in Immunoserology in Korea (2002).
Young Joo CHA ; Dong Gil KUM ; Sung Won KIM ; Think You KIM ; Jae Ryong KIM ; Hyon Suk KIM ; Myong Hee PARK ; Seong Hoon PARK ; Ae Ja PARK ; Han Chul SON ; Joo Suk YANG ; Kye Sook LEE ; Seok Lae CHAE
Journal of Laboratory Medicine and Quality Assurance 2003;25(1):51-71
The followings are the results for external quality assessment (EQA) in immunoserology for 2002: 1. Evaluation of EQA was done in 2 trials in May and November, about 96% of laboratories participating average 8.3 items. 2. In C-reactive protein (CRP), rheumatoid factor (RF) and anti-streptolysin O (ASO) tests, about 40%, 53% and 52% of the participating laboratories respectively have used qualitative assays, mainly latex agglutination. And about 55%, 43% and 40% of the participating laboratories have used quantitative assays, turbidimetric immunoassay (TIA) or nephelometry in CRP, RF and ASO tests respectively. Laboratories using TIA increased and those using nephelometry decreased. The instruments which were the most frequently used in nephelometry were BN series (Dade Behring Inc., Germany). The instruments of Hitachi series (Hitachi Ltd., Japan), Cobas Integra and Mira series (Roche Diagnostics GmbH, Germany), Toshiba series (Toshiba Corporation, Japan) and Olympus AU series (Olympus Optical Co., Ltd., Japan) were frequently used in TIA. The quantitative results were quite variable according to the methods or reagents, especially in RF and ASO. 3. Over 90% of participating laboratoreis have used imunoassay including enzyme immunoassay (EIA), microparticle EIA (MEIA), chemiluminescence immunoassay (CIA), immunochromatography assay (ICA) or radioimmunoassay (RIA). Laboratories using CIA and ICA increased. Sensitivities of ICA were lower than those of other immunoassays in the results of HBsAg and anti-HCV. The sensitivity of SD HCV (Standard Diagnostics, Inc., Korea) was especially lower in anti-HCV results. Sensitivities of CIA and ICA were also lower than those of EIA including MEIA in the results of anti-HIV. 4. The criteria of interpretation were considered to be evaluated in Widal test and laboratories using ICA increased in serological tests for syphilis.
Agglutination
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C-Reactive Protein
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Hepatitis B Surface Antigens
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Immunoassay
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Immunochromatography
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Immunoenzyme Techniques
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Indicators and Reagents
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Korea*
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Latex
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Luminescence
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Nephelometry and Turbidimetry
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Radioimmunoassay
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Rheumatoid Factor
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Serologic Tests
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Syphilis