1.Traumatic Extrapleural Hematoma Mimicking a Hemothorax.
Young Woo PARK ; Jae Wook LEE ; Dong Gi LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 2010;43(3):328-331
Extrapleural hematoma results from blood accumulating between the parietal pleura and the endothoracic fascia, whereas hemothorax shows pooling in the pleural space. Extrapleural hematoma results from an intact parietal pleura that blocks blood from escaping the pleural cavity. Extrapleural fat, a fat layer outside the pleura in the chest wall between the parietal pleura and the endothoracic fascia, is pathognomonic on computed tomography. We diagnosed traumatic extrapleural hematoma and treated it with video-assisted thoracic surgery. We report here on this case along with a review of the literature.
Fascia
;
Hematoma
;
Hemothorax
;
Pleura
;
Pleural Cavity
;
Thoracic Surgery, Video-Assisted
;
Thoracic Wall
;
Thoracoscopy
;
United Nations
2.Stimulation of melanogenesis by glycyrrhizin in B16 melanoma cells.
Gi Dong JUNG ; Jeong Yeh YANG ; Eun Sup SONG ; Jin Woo PARK
Experimental & Molecular Medicine 2001;33(3):131-135
Glycyrrhizin (GR), triterpenoid saponin composed of one glycyrrhetinic acid (GA) and two glucuronic acids, is a main constituent of the hydrophilic fraction of licorice (Glycyrrhiza glabra) extracts and is known to have a wide range of pharmacological actions. In this study, we investigated the mechanism of GR effect on melanogenesis in B16 murine melanoma cells. The cellular levels of tyrosinase mRNA, protein, enzyme activities and melanin contents were increased by GR in a dose dependent manner. Expression of tyrosinase-related protein-2 (TRP-2) mRNA was also increased by GR, however, no significant change was observed on TRP-1. No cytotoxicity was observed at the effective concentration range of GR. GA showed no effect on melanogenesis at the equivalent nontoxic concentrations, indicating that glycoside structure is important in the stimulatory effect of GR on melanogenesis. These results indicate that GR-induced stimulation of melanogenesis is likely to occur through the transcriptional activation.
Animal
;
Blotting, Western
;
Glycyrrhetinic Acid/pharmacology
;
Glycyrrhizic Acid/*pharmacology
;
Intramolecular Oxidoreductases/genetics/metabolism
;
Melanins/*biosynthesis
;
Melanoma, Experimental/enzymology/*metabolism
;
Mice
;
Monophenol Monooxygenase/genetics/metabolism
;
Proteins/genetics/metabolism
;
Reverse Transcriptase Polymerase Chain Reaction
3.Construction of an ideal set-up model for lingual orthodontic treatment.
Korean Journal of Orthodontics 2005;35(6):459-474
Making a precise and ideal set-up model is an essential part in the indirect bonding procedure for lingual orthodontic treatment. To evaluate the accuracy of the making a set-up model, 22 adult patients who received lingual orthodontic treatment with 4 bicuspid extractions were selected, and 3 sets of dental models (before, set-up, and after treatment) were measured using the set-up model gauge, an instrument for measuring the inclination and angulation of the clinical crowns on the dental model. Two sets of lateral cephalograms (before and after) from each patient were also evaluated. The mean difference between the before treatment model and the set-up model was -3.93 +/- 6.98 degrees for the inclination and 1.87 +/- 5.79 degrees for the angulation. And the mean difference between the set-up model and the after treatment model was -4.31 +/- 5.91 degrees labiolingually and -2.16 +/- 3.27 degrees mesiodistally. The after treatment model differed from the before treatment model about -8.24 +/- 5.39 degrees in inclination. There were no significant difference between the measured gauge that measured from the dental model using the set-up model gauge and the calculated gauge angle measured from the lateral cephalogram using constructed points and lines. Using the set-up model gauge, it is possible to evaluate the study model 3-dimensionally in relation with the patient's lateral cephalogram and establish whether the doctor's prescription or overcorrection is built in the set-up model precisely.
Adult
;
Bicuspid
;
Crowns
;
Dental Models
;
Humans
;
Prescriptions
4.Korean Pain Descriptors in Patients with Neuromusculoskeletal Pain
Gi Young PARK ; Dong Rak KWON ; In Ho WOO
Clinical Pain 2019;18(2):82-87
OBJECTIVE: To evaluate which Korean pain descriptors are frequently used in the patients with neuromusculoskeletal diseases and compare the frequency of Korean pain descriptor according to age, gender, pain pattern and intensity, and clinical diagnosis.METHOD: Two hundreds sixty nine patients with neuromusculoskeletal diseases were enrolled in this study. The patients were asked to fill out a pain questionnaire using Korean. The Korean pain descriptors were collected and classified according to neurophysiological mechanism. The frequency of Korean pain descriptor was analyzed by age, gender, pain pattern and intensity, and clinical diagnosis. They were divided into axial spine and peripheral joint pain group depending on the location of causal disease and shoulder pain descriptors were divided into intra-articular and bursa group.RESULTS: Among 24 Korean pain descriptors, ‘arida’ was the most common pain descriptor, followed by ‘ssusida’ and ‘jjireunda’. When the pain descriptors were classified according to neurophysiological mechanism, superficial somatic pain was the most common, followed by deep somatic pain. There was a significant difference in the frequency of the pain descriptor between axial spine and peripheral joint pain group (p=0.007). The pain descriptor ‘danggida’ was used significantly more in the patients with axial spine pain than peripheral joint pain (p=0.024). However, there was no significant difference in other factors.CONCLUSION: The patients with neuromusculoskeletal diseases expressed their pain using various Korean pain descriptors with stabbing nature and superficial somatic pain. Our results may be helpful to assess and develop a new Korean pain quality measure in the patients with neuromusculoskeletal diseases.
Arthralgia
;
Diagnosis
;
Humans
;
Methods
;
Musculoskeletal Pain
;
Neuralgia
;
Nociceptive Pain
;
Sensation
;
Shoulder Pain
;
Spine
;
Subject Headings
5.Phlegmonous Esophagitis Treated with Internal Drainage and Feeding Jejunostomy.
Won Gi WOO ; Young Woo DO ; Geun Dong LEE ; Sung Soo LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 2017;50(6):453-455
We report the case of a 67-year-old woman presenting with epigastric pain. Computed tomography identified diffuse phlegmonous esophagitis. Esophagogastroduodenoscopy revealed multiple perforations in the mucosal layer of the esophagus. A large amount of pus was drained internally through the gut. The patient was treated with antibiotics and early jejunostomy feeding. Although phlegmonous esophagitis is a potentially fatal disease, the patient was successfully treated medically with only a minor complication (esophageal stricture).
Aged
;
Anti-Bacterial Agents
;
Cellulitis*
;
Drainage*
;
Endoscopy, Digestive System
;
Esophagitis*
;
Esophagus
;
Female
;
Humans
;
Jejunostomy*
;
Suppuration
6.Two Cases of Successful Surgical Treatment of Postmyocardial Infarction Ventricular Septal Defect-Repeated Performation After the First Operation.
Ji Hyun LEE ; Byung Gyu NA ; Sang Woo OH ; Gi Byoung NAM ; Dong Woon KIM ; Myeong Chan CHO ; Youn Woo NO ; Jong Myun HONG ; Jae Ho AN
Korean Circulation Journal 1997;27(2):234-240
Mechanical complications of acute myocardial infarction which may lead to heart failure or shock include ruptute of left ventricular free wall, ventricular septum and papillary muscle. The clinical characteristics of these lesions vary conservative management alone has high mortality rate, for which reason surgical repair of these defects are essential. Structural defects including rupture of the left ventricular free wall, ventricular septum, and papillary muscle, accout for 5% to 20% of all deaths from acute myocardial infarction. Among these, ventricular septal defects occur in approximately 1% of all myocardial infarction, and account for up to 2% of deaths subsequent to myocardial infarction. Rupture of the ventricular septum following acute myocardial infarction(AMI) is associated with high mortality rate, as 54% of the patients succumb within two weeks, 87% within two months and 92.5% during the first year. We experienced two cases of postinfarct ventricular septal defects(VSD) which had been repaired within 1 week after AMI due to progressive deterioration of patients` conditions, and were to be reoperated because of repeated septal ruptures in postoperation period and development of cardiogenic shock.
Heart Failure
;
Heart Septal Defects, Ventricular
;
Humans
;
Infarction*
;
Mortality
;
Myocardial Infarction
;
Papillary Muscles
;
Rupture
;
Shock
;
Shock, Cardiogenic
;
Ventricular Septum
7.The effect of labial inclination on intrusion of the upper and lower incisors by three-dimensional finite element analysis.
Dong Woo KIM ; Hoon Chul YANG ; Gi Tae KIM ; Sung Sik KIM ; Woo Sung SON
Korean Journal of Orthodontics 2003;33(4):259-277
This study was designed to investigate the position of anteroposterior center of resistance for genuine intrusion and the mode of change of the minimum distal force for simultanous intrusion and retraction of the upper and lower incisors according to the increase of labial inclination. For this purpose, we used the three-piece intrusion arch appliance and three-dimensional finite element models of upper and lower incisors. 1. Positions of the center of resistance in upper incisors according to the increase of the labial inclination were as follows; 1) In normal inclination situation, the center of resistance was located in 6mm behind the distal surface of the lateral incisor bracket. 2) In 10degrees increase of the labial inclination situation, the center of resistance was located in 9mm behind the distal surface of the lateral incisor bracket. 3) In 20degrees increase of the labial inclination situation, the center of resistance was located in 12m behind the distal surface of the lateral incisor bracket. 4) In 30degrees increase of the labial inclination situation, the center of resistance was located in 16m behind the distal surface of the lateral incisor bracket. 2. Positions of the center of resistance in lower incisors according to the increase of the labial inclination were as follows; 1) In normal inclination situation, the center of resistance was located in 10mm behind the distal surface of the lateral incisor bracket. 2) In 10degrees increase of the labial inclination situation, the center of resistance was located in 13mm behind the distal surface of the lateral incisor bracket. 3) In 20degrees increase of the labial inclination situation, the center of resistance was located in 15m behind the distal surface of the lateral incisor bracket. 4) In 30degrees increase of the labial inclination situation, the center of resistance was located in 18m behind the distal surface of the lateral incisor bracket. 3. The patterns of stress distribution were as follows; 1) There were even compressive stresses in and periodontal ligament when intrusion force was applied through determined center of resistance. 2) There were gradual increase of complexity in compressive stress distribution pattern with increase of the labial inclination when intrusion and retraction force were applied simultaneously.
Finite Element Analysis*
;
Incisor*
;
Periodontal Ligament
8.Rhabdomyolysis associated with lovastatin-cyclosporine combination therapy : report of three cases in kidney transplant recipients.
Ki Dong YOO ; Won Young LEE ; Gi Won PARK ; Chul Woo YANG ; Dong Chan JIN ; Sun Ae YOON ; Young Suk YOON ; Byung Kee BANG
Korean Journal of Nephrology 1993;12(4):715-719
No abstract available.
Kidney*
;
Rhabdomyolysis*
;
Transplantation*
9.Relationship between Metabolic Acidosis and Nutritional Parameters in Stable Hemodialysis Patients.
Kun Hoo KWON ; Jae Soo LEE ; Yong Bum CHO ; Dong Han GI ; Seoung Woo LEE ; Moon Jae KIM
Korean Journal of Nephrology 1999;18(2):301-306
To evaluate the nutritional status according to the degree of metabolic acidosis(MA) and determine that MA is a risk factor for malnutrition, we screened the laboratory data of 37 hemodialysis(HD) patients who were clinically stable for more than 6 months and taken bioelectrical impedence analysis(BIA) twice 6 months apart to check lean body mass (LBM). Mean age of patients was 49.1+/-15.0 years and sex ratio 1:2.4. Mean serum albumin level was 3.97+/-0.36g/dl and weekly Kt/V and normalized protein catabolic rate(nPCR) were 3.04+/-0.85 and 0.99+/-0.21g/kg/day. According to mean total CO2 content during the periods between BIA, the patients were divided to three groups[group 1(n=16):&18mEq/L, group 2(n=9):18< or =tCO2&21mEq/L, group 3(n=12):> or =21mEq/L). Group 1 had significantly higher body weight gain than group 2 and 3(1.82+/-1.62 vs. 0.77+/-3.13 and 1.35+/-3.85kg, P<0.05), and higher LBM gain(1.99+/-4.38 vs. 3.35+/-7.99kg, P<0.05), nPCR(1.05+/-0.20 vs. 0.91+/-0.13g/kg/day, P<0.05), intact parathyroid hormone(88.4+/-78.7 vs. 32.0+/-26.5pg/ml, P< 0.05), and phosphate(5.4+/-1.3 vs. 3.9+/-1.3mg/dl, P< 0.05) than group 3. There were no differences in age, serum albumin, BUN, creatinine and weekly Kt/V among three groups. Mean total CO2 level was inversely correlated with body weight gain and LBM gain. In conclusion, metabolic acidosis in stable HD patients may be the result of high protein intake and not related to decrease of body weight by protein catabolism.
Acidosis*
;
Body Weight
;
Creatinine
;
Humans
;
Malnutrition
;
Metabolism
;
Nutritional Status
;
Renal Dialysis*
;
Risk Factors
;
Serum Albumin
;
Sex Ratio
10.Anticoccidial effects of the root bark of Dictamnus dasycarpus Turcz extract on experimental Eimeria tenella infection.
Sunhwa HONG ; Hyun A LEE ; Dong Woo KIM ; Gi Wook OH ; Okjin KIM
Laboratory Animal Research 2014;30(4):169-173
Anticoccidial effects of the root bark of Dictamnus dasycarpus Turcz (Rutaceae) extract (DDE) were evaluated in chickens following oral infection with Eimeria (E.) tenella. Three-day-old chickens (n=30) were assigned to three groups (control, untreated, and DDE 0.1% treated). Chickens were fed a standard diet supplemented with or without DDE for 1 week prior to infection with E. tenella (10,000 sporulated oocysts per chicken). The effects of DDE on E. tenella infection were assessed by two parameters; fecal oocysts shedding and body weights gain. The DDE-fed chickens produced significantly reduced fecal oocysts (P<0.05) when compared to the E. tenella-infected group fed standard diet. Also, DDE-based diet, improved body weight loss caused by E. tenella infection. Our data demonstrated that DDE had remarkable anticoccidial activities against E. tenella. This finding might have implications for the development of anticoccidial drug. This study is the first to demonstrate anticoccidial effect of DDE on Eimeria parasites.
Body Weight
;
Chickens
;
Dichlorodiphenyl Dichloroethylene
;
Dictamnus*
;
Diet
;
Eimeria
;
Eimeria tenella*
;
Oocysts
;
Parasites
;
Rutaceae