Posterior capsule opacification(PCO) is a common complication of cataract surgery. The presence of a posterior chamber intraocular lens has been shown to decrease the incidence of the development of PCO. Moreover, there are evidences that the design of intraocular lens may also alter its development. Extracapsular lens extraction with implantation of posterior chamber lens were operated on a consecutive series of 230 eyes. These were evaluated in the viewpoint of PCO development after surgery. All were sulcus fixed and their optic designs were devided into two groups; a group of convex-plano lens with continuous laser ridge including convex-concave lens and a group of biconvex lens. The incidence of PCO was lower in convex-plano lens with continuous laser ridge group(6.7%) than that of boconvex lens group(18.9%). The incidence of Nd:YAG posterior capsulotomy marked 0.0% in continuous ridged group and 1.8% in biconvex group(p<0.05, p Capsule Opacification* ; Cataract ; Incidence ; Lenses, Intraocular* ; Posterior Capsulotomy

The amino acid L-glutamate is a major excitatory neurotransmitter in central nervous system of vertebrates. NMDA( n-methyl-d-aspartate) is one of the L-glutamate receptor subtypes. During a critical period of early postnatal development, the visual cortex is susceptible to experience-dependent modification of neuronal response. Recently, the activation of NMDA receptors has been supposed as an prerequisite for the induction of such modification We therefore investigated developmental changes of NMDA receptors in rat visual cortex and questioned whether they could be related to the visual development. We assessed the density of [3H] NMDA receptor in visual cortex of normally reared rats (Group I) and visually deprivated rats (Group II) using quantitative autoradiography. The density of [3H] NMDA receptor was increased rapidly by postnatal 1 week and decreased after postnatal 5 weeks, and was significantly lower in Group II than Group I during early postnatal period. These results suggest that NMDA receptors may have a role in neuronal development in visual cortex.
Animals ; Autoradiography ; Central Nervous System ; Critical Period (Psychology) ; Glutamic Acid ; N-Methylaspartate* ; Neurons ; Neurotransmitter Agents ; Rats* ; Receptors, N-Methyl-D-Aspartate* ; Vertebrates ; Visual Cortex*

The amino acid L-glutamate is a major excitatory neurotransmitter in the central nervous system of vertebrates(1). NMDA (N-methyl-d-aspartate) is one of the L-glutamate receptor subtypes(2). During a critical period of early postnatal development, the visual cortex is susceptible to experience-dependent modification of neuronal responses. Recently, the activation of NMDA receptors has been supposed as a prerequisite for the induction of such modification(3). We therefore investigated developmental changes of NMDA receptors in the rat visual cortex and questioned whether they could be related to the visual development. We assessed the density of [(3)H]-NMDA receptor in the visual cortex of normally reared rate (Group I) and visually deprived rats (Group II) using quantitative autoradiography(4). The density of [(3)H]-NMDA receptor was significantly lower in Group II than in group I during the early postnatal period, and increased rapidly by postnatal 1 week and, decreased after postnatal 5 weeks. These results suggested that NMDA receptors may play a role in neuronal development in the visual cortex during the early postnatal period.
Animals ; Autoradiography ; Dark Adaptation ; Eyelids/surgery ; Glutamates/metabolism ; Glutamic Acid ; Light ; Rats ; Receptors, N-Methyl-D-Aspartate/*metabolism ; Visual Cortex/growth & development/*metabolism

A 18-month-old girl was seen because of an yellowish brown papular eruptions on the face, earlobes and neck of one year duration. A skin biopsy specimen revealed circumscribed cellular infiltrates composed of predorninantly pleornorphic histiocytes. Electron microscopy of biopsy material disclosed numerous worm like particles and coated vescles in limited area of the cell cytoplasm, consistent with the findinga described in benign cephalic histiocytosis. After six months of her first visit, the individual papules became flattened.
Biopsy ; Coated Vesicles ; Cytoplasm ; Female ; Histiocytes ; Histiocytosis* ; Humans ; Infant ; Microscopy, Electron ; Neck ; Skin

This study was performed to evaluate the correlationship between posterior capsular opacification and optic configuration of intraocular lens in extracapsular lens extraction with In-the-bag implantation of posterior chamber lens. We retrospectively studied the 455 cases of cataract operations that were performed between January 1993 and January 1995. All were in-the-bag placement and their optic designs were divided into two groups: a group of biconvex lens and a group of convex-plano lens with continuous laser ridge. The incidence of PCO in bicovex lens group was 7.0% and that of convex plano lens with laser ridge group was 7.1%. The difference in the rate of posterior capsular opacification between two groups was not statistically significant. The incidence of Nd: YAG laser posterior capsulotomy revealed 0.0% in continuous ridged group and 2.6% in biconvex group(p>0.05).
Capsule Opacification* ; Cataract ; Incidence ; Lasers, Solid-State ; Lenses, Intraocular* ; Posterior Capsulotomy ; Retrospective Studies

Hemangioma appearing on the conjuntiva is a rare benign tumor which may be derived from vessels of conjuntiva, sclera, ocular muscles and orbit. Recently, we have experienced two cases of well encapsulated movable, round and slightly nodular conjuntival masses which had smooth, dark bluish-red colored surfaces. The masses were simply excised and histopathologic study revealed cavernous hemangioma.
Hemangioma ; Hemangioma, Cavernous* ; Muscles ; Orbit ; Sclera

Warrdenburg's syndrome, a rare hereditary disease, may be transmitted as an irregular autosomal dominant traits, which is distinguished by lateral displacement of the medial canthi and inferior lacrimal puncta, broad and prominant nasal root, hyperplasia of the medial portions of the eye-brows, white or grey colored forelock, partial or total heterochromia of the irides, congenital deafness, etc. Recently, the authors have experienced three cases of Waardenburg's syndrome in one family. They were 29 year old male, his 4 year old son and 3 year old daughter. We report these interesting cases with a brief review of literatures.
Adult ; Child, Preschool ; Deafness ; Genetic Diseases, Inborn ; Humans ; Hyperplasia ; Male ; Nuclear Family ; Waardenburg Syndrome*

A 61-year-old korean male had noticed a growth on his left eye for the last 3 monthes. This had begun at the nasal limbus of his cornea and had spread over the surface of the cornea. The patient had undergone surgery for the removal of a "tumor on his stomach", about 3 years before, but, no further information concerning this was obtainable. The elevated mass was removed easily by simple excision, and the diagnosis was confirmed histopathologically as "conjunctival carcinoma in situ".
Carcinoma in Situ* ; Cornea ; Diagnosis ; Humans ; Male ; Middle Aged

Zonular traction tufts, which exist in 15% of normal population, do not cause retinal detachment by themselves but they can cause traction retinal detaehment when there is traction force added. It is thought that the possibility of development of retinal detaehment increases especially when zonular traetion tufts originate posterior to the vitreous base No case of traction retinal detachment caused by zonular traction tufts has been reported. Here, we report one suspected case of traction retinal detachment induced by zonular traction tufts and lens subluxation.
Lens Subluxation ; Retinal Detachment* ; Retinaldehyde* ; Traction*

We tried extracapsular cataract extraction and PCL implantation with Ocutome-FragmatomeII System and Disposable Two-Way Needle. 160 eyes were operated with this method, 101 eyes were followed up over 2 months period. Clinical results were not significantly different from previous reports of ECCE and PCL implantaion. Corrected visual acuity 0.5 or better after 2 months of surgery were 95%. No serious intra-operative and post-operative complications were noted. We suggest Ocutome-FragmatomeII System and Disposble Two-Way Needle could be used for ECCE and PCL implantation in case of absence of I and A system.
Cataract Extraction* ; Cataract* ; Needles* ; Visual Acuity