No abstract available.
Venous Thrombosis

Transmitral left ventricular diastolic inflow velocities determined by pulsed Doppler in 47 normotensives, 80 hypertensives and 44 age-matched hypertensives were measured to evaluate the effects of age and left ventricular hypertrophy on left ventricular diastolic fuction in normotensives and hypertensives. The results were as follows: 1) The peak E velocity in normotensives(77.82+/-13.53cm/sec) was significantly different from those of hyeprtensives(58.13+/-11.80cm, p<0.01) and age-matched hypertensives(59.31+/-10.94cm/sec, p<0.01). The peak E/A in normotensives(1.31+/-0.45) was significantly different from those of hypertensives(0.83+/-0.21,p<0.01) and age-matched hypertensives(0.83+/-0.20, p<0.01). 2)In normotensives, simple linear regression analysis revealed strong inverse correlations of peak E with age(r=-0.758, p<0.01), peak E/A with age(r=-0.748, p<0.01), but no significant correlation of peak E and peak E/A with LVMI(p>0.05). Stepwise regression analysis revealed that age was the most important correlate of peak E and peak E/A in normotensives(peak E: R
Heart Diseases ; Hypertrophy, Left Ventricular* ; Linear Models

No abstract available.
Child* ; Fetal Growth Retardation* ; Growth Hormone* ; Humans

No abstract available.
Constriction, Pathologic* ; Sutures* ; Trachea*

A case of testicular embryonal carcinoma developed in s cryptorchid testis is presented with a review of the literature. According to Campbell's series, the incidence of malignant cryptorchid testis was 11.6%. and his statistical evaluation was similar to Gilbert and Hamilton's series of 7,000 cases of testicular neoplasms where 840 tumors were developed in undescended testes(12%). Both authors agree that the chance of neoplastic development in a cryptorchid testis is approximately 48 times greater then that developing in a normally descended testis. Several cases of testicular tumor were reported sporadically in Korea, but malignant tumors in cryptorchism were rarely seen in the literatures Only two cases of malignant cryptorchid testis were already reported in Korea.
Carcinoma, Embryonal* ; Cryptorchidism ; Incidence ; Korea ; Male ; Testicular Neoplasms ; Testis*

The primary goal of treatment of the adult ankle fracture is to effect the returning of normal func tion that is accomplished by the accurete reduction and rigid internal fixation followed by the early institution of motion. The authors have reviewed a series of 41 cases of the bimalleolar and trimalleolar ankle fractures that treated in Orthopedic Department of Eulji General Hospital, Seoul, from January 1982 to June 1986. With the duration of follow-up of average 13.2 months, we summarized the obtaind results as followings. l. Among the forty one patients, thirty one was male patient(M: F =3.1: 1). The average age was 33.2 years old. 2. The main cause of the fracture was traffic accident, 18 cases(43.9%) and other causes were slipping down(24.4%), fall from a height(14,6%), industrial injury(12.2%) and other injuries(4.9%). 3. According to the modified Lauge-Hansens classification, the supination-external type was most common (41.5%). 4. As a diagnostic method, the computerized tomography was also available. 5. All cases were treated by open reduction and internal fixation with the good radiologic results of 91.3% in bimalleolar fractures and 88.9% in trimalleolar fractures. 6. Of the bimalleolar fractures, ten patientz showed normal range of motion in 2 to 4 weeks, average 18.4 days, by early joint exercise.
Accidents, Traffic ; Adult ; Ankle Fractures ; Ankle ; Classification ; Clinical Study ; Follow-Up Studies ; Hospitals, General ; Humans ; Joints ; Male ; Methods ; Orthopedics ; Reference Values ; Seoul

27 Colles' fracture were treated with closed reduction and percutaneous k-wire fixation under the C-arm fields, from July 1980 to September 1984 at the Department of Orthopedic Surgery of Eul Ji Hospital. The average duration of the follow up was 4.9 Months. A prospective study was made and evaluated under the subjective and objective criteria of Gartland and Werley, and the objective criteria of Scheck. The results of this study were as follows: 1. The incidence was high in 4th and 5th decade as 66. 5%, not significant between females and males, 45% of the cause of injury was falling accident. 2. In 27 cases, showed the satisfactory result about 92.6%, but, in the eomminuted intraarticular fracture group, 2(15.4%) out of 13 cases showed unsatisfactory result. 3. Better result was obtained with more secure reduction and skillful technique, in certain case, considered that the open reduction and internal fixation with k-wires would be better than percutaneous k-wire fixation. 4. In the aspect of hand motion and the concept of improved anatomical restoration and maintenance would lead to improved function, ideal method was percutaneous k-wire fixation and casting after closed reduction under the C-arm fields.
Accidental Falls ; Colles' Fracture ; Female ; Follow-Up Studies ; Hand ; Humans ; Incidence ; Intra-Articular Fractures ; Male ; Methods ; Orthopedics ; Prospective Studies

No abstract available.
Skull Base* ; Skull*

No abstract available.
Cytomegalovirus Infections* ; Cytomegalovirus* ; Incidence*

BACKGROUND: During normal wound healing the formation of scars and fibrous tissue occurs, which consists largely of collagen fibril, but excessive fibrosis and scar formation become clinical problems. Collagen remodelling during scar formation is dependent on both continued collagen synthesis and collagen catabolism. Halofuginone, a plant alkaloid, is known to inhibit collagen type I synthesis at the transcriptional level. OBJECTIVE: The purposes of this study were to investigate the effects of topical application of halofuginone on the healing of wounds. METHOD: Topical solutions containing halofuginone of variable concentrations were applied on the full-thickness excisional wounds of hairless mice and 0.1% halofuginone ointments applied on the suture site of rats and the normal skin of hairless mice daily. In addition, we performed a one-time intradermal injection of 0.1% halofuginone solution on the normal skin of the hairless mice. We examined the collagen content of the skin of hairless mice and rats treated with halofuginone solutions and ointments during the healing process by performing hematoxylin-eosin and Masson's trichrome stains. We assessed, from time to time, the change in the full-thickness excisional wound size of hairless mice treated with halofuginone solutions of variable concentrations during the healing process and observed clinically the healing process of hairless mice with the full-thickness excisional wound. RESULT: 1. The wound size after daily application of 0.001% and 0.1% halofuginone solutions on the full-thickness excisional wounds of hairless mice decreased more slowly in comparison with the control group (p < 0.05).
Animals ; Cicatrix ; Collagen ; Collagen Type I ; Coloring Agents ; Fibrosis ; Injections, Intradermal ; Metabolism ; Mice ; Mice, Hairless ; Ointments ; Plants ; Rats ; Skin ; Sutures ; Wound Healing* ; Wounds and Injuries*