2.Congenital Tracheoesophageal Fistula without Atresia of the Esophagus.
Dong Hyup LEE ; Cheol Joo LEE ; Hyun Sik MIN
Yeungnam University Journal of Medicine 1985;2(1):253-258
The congenital tracheoesophageal fistula without atresia of the esophagus is considered a rare variant, and the literature concerned to the tracheoesophageal fistula fistula without atresia is little in adult especially. The 22-year-old male was admitted to Yeungnam University Hospital with his chief complaints of weight loss (6 kg/6 months), abdominal discomfort, and intermittent coughing. The diagnosis was made by the endoscopy and esophagography. The fistula was 1.5 cm in diameter, 0.5 cm in length. The level was around second thoracic vertebra. The operation was performed transpleurally through the right third intercostals space and the fistula was secured with interrupted silk suture after division. The fibrotic adhesion was seen around the tracheoesophageal fistula. The postoperative course was uneventful, and postoperative esophagogram revealed no extraluminal leakage. Herewith we report this unusual case of isolated tracheo-esophageal fistula with review of literatures.
Adult
;
Cough
;
Diagnosis
;
Endoscopy
;
Esophagus*
;
Fistula
;
Humans
;
Male
;
Silk
;
Spine
;
Sutures
;
Tracheoesophageal Fistula*
;
Weight Loss
;
Young Adult
3.A study of peripheral blood eosinophil and serum IgE level in patients with atopic dermatitis.
Dong Geun KANG ; Chun Wook PARK ; Cheol Heon LEE
Korean Journal of Dermatology 1992;30(1):51-56
The peripheral blood eosinophil and serum IgE level in 53 patients with atopic dermatitis (AD) were measured. The patients were divided into 2 groups by severity(mild and severe grous) and into 3 groups by the associated respiratory atopic deseases and/or their family history : respiratory group(patient, with both AD and respiratory atopy), family history group (patient with both AD and family history of respiratory atopy), and atopic group(patient with neither respiratory atopy nor family history of respiratorv atopy). We designed to study which factors are important in the elevation of serum IgE and peripheral blood eosinophil level in AD, and to know possible relationships between the serum eosinophil and IgE level and the several groups of AD. The results are as follows : 1. Peripheral eosinophil counts were higher in severe group(224.8/mm) than in mild group (180.0/mm)(p<0.05). 2. Peripheral eosinophil counts were 220.0/mm in atopic group, l65.0/mm in family history group, and 332.4/mm in respiratory group, but there was no stitistically significant difference among 3 groups. This suggests that concomitant respiatitiry atopy or a family history of respiratory atopy is not an important factor in the elvation of peripheral blood eosinophil counts in AD. 3. Serum IgE was higher in severe group(443.2IU/ml) than in mild group(231.5IU/ml)(p<0.05). 4. Serum IgE level in respiratory group(754.6IU/ml) were signifiiantlly higher than in atopic (286.6IU/ml) or family history group(342.0IU/ml)(p<0,01). But there was no significant. difference between family and atopic group. This result suggests that concomittent respiratory atopy is a potential factor in elevation of serurn Igi in AD. 5. Slightly high correlation between peripheral blood and IgE level appeared in all 53 patients (r=0.434) and severe group(r=0.480). But, respiratory group(r=0.060), family history group(r=0.111) and atopic group(r=0.202) showed poor relationships.
Dermatitis, Atopic*
;
Eosinophils*
;
Humans
;
Immunoglobulin E*
4.A Case of Epidermodyspalsia Verruciformis Associated with Squamous Cell Carcinoma.
Dong Un KIM ; Cheol Heon LEE ; Hong Jig KIM
Korean Journal of Dermatology 1981;19(2):227-231
A case of epidermodysplasia verruciformis associated with squamous cell carcinoma occurred in 21 years old male. He had extensive flat-topped papules on the face, neck and the upper trunk, and verrucous lesions on the extremities, especially on the dorsa of hands and feet for 15 years. Several peanut sized ulcerative lesions on the forehead were noticed for 1 year and identified as squarnous cell carcinomi. The akin test with dinitrochlorobenzene, tuberculin, phytohemagglutinin, candidin and dermatophytin showed alI negative. T and B-cell counts were within norrnal limits, but IgG and IgD levels in serurn were incresed.
B-Lymphocytes
;
Carcinoma, Squamous Cell*
;
Dinitrochlorobenzene
;
Epidermodysplasia Verruciformis
;
Extremities
;
Foot
;
Forehead
;
Hand
;
Humans
;
Immunoglobulin D
;
Immunoglobulin G
;
Male
;
Neck
;
Tuberculin
;
Ulcer
;
Young Adult
5.Antiviral action of aloe extracts.
Pyung Woo LEE ; Yun Cheol KIM ; Dong Hoon CHUNG
Journal of the Korean Society of Virology 1992;22(2):207-215
No abstract available.
Aloe*
6.Maaji virus: I. identification and antigenic characterization of a new Hantavirus isolated from apodemus mice(apodemus agrarius coreae ) in Korea.
Pyung Woo LEE ; Dong Hoon CHUNG ; Yun Cheol KIM
Journal of the Korean Society of Virology 1992;22(2):187-196
No abstract available.
Animals
;
Hantavirus*
;
Korea*
;
Murinae*
7.A Case of Reiter's Syndrome : Treated with Prednisolone and Methotrexate.
Cheol Heon LEE ; Dong Un KIM ; Hong Jig KIM
Korean Journal of Dermatology 1981;19(1):105-109
We experienced a case of Reiter's syndrome. A 20-year-old Korean male patient of Reiter's syndrome was reported. He had been suffered from mucopurulent urethral discharge, followed by white scaly patches on the skin, fever, transient conjunctivitis and arthralgia. Initially he was treated with sodium salicylic acid (Aspirin), indomethacin 150 mg/day for arthralgia and prednisolone 30mg/day. In accordance with improvement of symptom., prednisolone was tapered to 12. 5mg, when methotrexate 20mg/wk was added for the prevention of side effects of long term use of corticosteroids, Conjunctivitis, arthritis, and skin lesions cleared within 7 months. With improvement of symptoms, prednisolone was tapered and methotrexate also was tapered slowly. Physical therapy for joint stiffness was done.
Adrenal Cortex Hormones
;
Arthralgia
;
Arthritis
;
Conjunctivitis
;
Fever
;
Humans
;
Indomethacin
;
Joints
;
Male
;
Methotrexate*
;
Prednisolone*
;
Salicylic Acid
;
Skin
;
Sodium
;
Young Adult
8.Linear Sebaceous Hyperplasia.
Dong Geun KANG ; Chun Wook PARK ; Cheol Heon LEE
Annals of Dermatology 1992;4(1):45-48
We report an unusual case of sebaceous hyperplasia in an 18-year-old male manifestated clinically as yellowish, grouped papules with a linear distribution, present on the right side of forehead since birth. Histopathologically, a large sebaceous gland composed of numerous lobules grouped around a centrally dilated duct was seen. The sebaceous lobules distributed in the upper dermis showed direct connection to the skin surface, which suggested a transepidermal elimination of sebaceous lobules.
Adolescent
;
Dermis
;
Forehead
;
Humans
;
Hyperplasia*
;
Male
;
Parturition
;
Sebaceous Glands
;
Skin
9.EXPRESSION OF TGF-alpha AND TGF-beta
Hee Chang YANG ; Dong Keun LEE ; Eun Cheol KIM
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons 1997;19(4):414-434
9,10-Dimethyl-1,2-benzanthracene
;
Animals
;
Carcinogenesis
;
Carcinoma in Situ
;
Carcinoma, Squamous Cell
;
Cricetinae
;
Cytoplasm
;
Epigenomics
;
Epithelium
;
Islands
;
Mineral Oil
;
Mouth Neoplasms
;
Mucous Membrane
;
Prognosis
;
Transforming Growth Factor alpha
;
Transforming Growth Factor beta
;
Transforming Growth Factors
10.Identification of the German Cockroach Allergens in Korean Atopy Using SDS - PAGE and Western Blot Analysis.
Chun Wook PARK ; Sang Dong KIM ; Cheol Heon LEE ; Dong Kyu LEE
Annals of Dermatology 2000;12(4):247-251
BACKGROUND: Cockroaches are important components of house dust allergens. In spite of significant subject reactivity to cockroach extracts, the specific source of the allergen remains unclear. OBJECTIVE: This study was performed to identify the important allergens in German cockroach whole body (GWBE), egg (GEE) and fecal (GFE) extracts in Korean atopy, and to compare the reactivity of GWBE and GEE by Western blot inhibition. METHODS: Sera from 11 subjects with Korean atopy were used for sodium dodecil sulfate polyacrylamide gel elctrophoresis (SDS-PAGE) and Western blot analysis. RESULTS: Allergenic fractions in German cockroach extracts were numerous and distributed throughout the wide range of molecular weights. The important allergens of GWBE, GFE and GEE were similar to each other by using SDS-PAGE and Western blot ysis. The aUergen bands at 55 kd showed the most significant reactivity; in GWBE, GFE and GEE 73%, 82%, 55%, respectively. Other bands exhibiting significant activity were the 67 kd band with 37%, 19% and 19%, the 64 kd band with 64%, 37% and 9% respectively. Furthermore, Western blot inhibition investigations revealed that either GWBE or GEE could almost completely inhibit the reactivity of the other extract. CONCLUSION: This study confirms that the 55 kd allergen can be considered as the major allergen in Korean atopy and demonstrated that the GWBE and GEE antigens have identical IgE-binding sites.
Allergens*
;
Blattellidae*
;
Blotting, Western*
;
Cockroaches
;
Dust
;
Electrophoresis, Polyacrylamide Gel
;
Molecular Weight
;
Ovum
;
Sodium