Exhaled breath analysis technology is a non-invasive,painless,safe,convenient,and efficient detection method.It holds great promise in disease screening,clinical diagnosis,assessment of disease severity,formulation of treatment plans,and prediction of disease prognosis.In recent years,this technology has rapidly ad-vanced and has become an important tool in the management of respiratory system diseases.This article aims to pro-vide a brief overview of the clinical applications and research progress of common exhaled breath analysis technolo-gies in respiratory system diseases such as airway chronic inflammatory diseases and airway infectious diseases.