1. A pilot study of antioxidant potential of endophytic fungi from some Sudanese medicinal plants
Afra KHIRALLA ; Rosella SPINA ; Dominique LAURAIN-MATTAR ; Afra KHIRALLA ; Rosella SPINA ; Dominique LAURAIN-MATTAR ; Afra KHIRALLA ; Ietidal MOHAMED ; Sakina YAGI ; Justinne THOMAS ; Benoît MIGNARD
Asian Pacific Journal of Tropical Medicine 2015;8(9):701-704
Objective: To evaluate the total phenolic content and total antioxidant capacity of ethyl acetate extracts of 21 endophytic fungi isolated from five Sudanese medicinal plants: Calotropis procera, Catharanthus roseus, Euphorbia prostrate, Vernonia amygdalina and Trigonella foenum-graecum. Methods: Crude extracts of endophytic fungi and their host plants were tested by classical Folin-Ciocalteu colorimetric method to determine the total phenolic content, also total antioxidant capacity was estimated using 1,1-diphenyl-2-picrylhydrazyl free radical scavenging in vitro method. Results: Among the endophytes, endophytic fungus Aspergillus sp. from Trigonella foenum-graecum seeds demonstrated the highest both total phenolic content in term of gallic acid equivalent [(89.9 ± 7.1) mg GAE/g] and antioxidant activity for 1,1-diphenyl-2-picrylhydrazyl radical scavenging assay [IC
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