1.The Usefulness of Dobutamine Stress Echocardiography for Evaluation of Viable Myocardium in Hibernating Myocardium.
Korean Circulation Journal 1998;28(8):1233-1236
No abstract available.
Dobutamine*
;
Echocardiography, Stress*
;
Myocardium*
2.Myocardial uptake and clearnace of thallium-201 in normal subjects:a comparison between pharmacologic stress with intravenous adenosine, dipyridamole and dobutamine, and exercise stress testing.
Jae Tae LEE ; Byung Chun CHUNG ; Jung Il CHOI ; Dong Suk KWAK ; Kyu Bo LEE ; Shung Chull CHAE
Korean Journal of Nuclear Medicine 1993;27(1):35-50
No abstract available.
Adenosine*
;
Dipyridamole*
;
Dobutamine*
;
Exercise Test*
3.The Safety and Utility of Dobutamine Stress Echocardiography for Pre-operative Risk Stratification in Orthotopic Liver Transplantation
Korean Circulation Journal 2018;48(9):836-838
No abstract available.
Dobutamine
;
Echocardiography, Stress
;
Liver Transplantation
;
Liver
4.Usefulness of dobutamine stress echocardiography in the diagnosis of coronary artery disease.
Heung Sun KANG ; Chung Whee CHOUE ; Kwon Sam KIM ; Myung Shick KIM ; Jung Sang SONG ; Jong Hoa BAE
Journal of the Korean Society of Echocardiography 1993;1(2):169-177
No abstract available.
Coronary Artery Disease*
;
Coronary Vessels*
;
Diagnosis*
;
Dobutamine*
;
Echocardiography, Stress*
5.Is Needed Dobutamine Stress Echocardiography for the Detection of Coronary Artery Stenosis in Women?.
Journal of Cardiovascular Ultrasound 2016;24(2):110-111
No abstract available.
Coronary Stenosis*
;
Coronary Vessels*
;
Dobutamine*
;
Echocardiography, Stress*
;
Female
;
Humans
6.Low-dose adenosine echocardiography for detection of myocardial viability in patients with acute myocardial infarction..
Li-Gang FANG ; Juan LI ; Wei CHEN ; Wen-Ling ZHU ; Quan FANG
Chinese Journal of Cardiology 2009;37(3):223-226
OBJECTIVETo evaluate the value of low-dose adenosine echocardiography (LDAE) for detection of myocardial viability in patients with acute myocardial infarction (MI).
METHODSThirty-six patients underwent LDAE within 3 - 10 days after onset of first acute MI before (n = 4) or after (n = 32) percutaneous coronary intervention. A 17-segment semi-quantitative scoring model was adopted. Wall motion improvement derived from two dimensional images at follow-up (2 - 3 months after acute MI) comparing baseline before adenosine infusion was used as gold criteria for myocardial viability.
RESULTSLow-dose adenosine slightly increased heart rates [(70.7 +/- 10.8) beats/min vs. (78.1 +/- 10.9) beats /min, P < 0.01] and also significantly reduced left ventricular endsystolic volume [(30.4 +/- 1.9) ml vs. (20.1 +/- 9.3) ml, P < 0.01] and increased ejection fraction (62.6% +/- 10.4% vs. 74.7% +/- 9.8%, P < 0.01). The sensitivity, specificity, diagnostic accuracy, positive and negative prective values of LDAE for identification of viable myocardium were 90.3%, 80.8%, 86.0%, 84.8% and 87.5%, respectively. Incidence of mild adverse reaction during LDAE was 38.9% (14/36). LDAE at dose of 100 microgxkg(-1)xmin(-1) was ideal in terms of balanced sensitivity and specificity for detecting viable myocardium without increasing the adverse effects compared to lower doses.
CONCLUSIONSLDAE (100 microgxkg(-1)xmin(-1)) has excellent sensitivity and specificity for detecting viable myocardium in acute MI with only minimal adverse effects.
Adenosine ; Dobutamine ; administration & dosage ; Echocardiography ; Humans ; Myocardial Infarction ; Myocardium
7.Effect of Tetrahydroisoquinoline Alkaloids on the alpha-adrenoceptors in Rat Aorta and Brain Homogenates.
Hyun Seok LEE ; Sun Ha PAEK ; Soo Hyun HWANG ; In Sung PARK ; Eun Sang KIM ; Myung Jin JUNG ; Jong Woo HAN ; Ki Churl CHANG
Journal of Korean Neurosurgical Society 1999;28(1):5-12
Tetrahydroisoquinoline(THI) alkaloids can be considered as cyclized derivatives of simple pthylamines and many of them, especially with 6,7-disubstitution, demonstrate relatively high affinity for catecholamines. In the present study, pharmacological action of limited series of THI has been examined using rat isolated atria and aorta. In addition, (H) prazosin displacement binding study with THI compounds using rat brain homogenates was performed to find out if these probes to have a-adrenoceptor affinity. In isolated rat atria, all THls and dobutamine increased heart rate and contractile force. In the presence of propranolol, the concentration response curves of YS 49 and YS 51 shifted to the right resulting in 8.07+0.84 and 7. 93+0.11 of pA values, respectively. The slope of each compound was not deviated from unity, indicating that these chemicals are highly competitive at the cardiac beta1-adrenoceptors. YS 49, YS 51 and higenamine showed alpha1- adrenoceptor affinity in rat brain in which the dissociation constant(K,) was 2.75, 2.81 and 1.02pM, respectively. It is concluded, therefore, that THI alkaloids have considerable affiniyt to alpha1-adrenoceptors in rat aorta and atria. while these probes show relatively high affinity for cardiac beta1-adrenoceptors. The authors speculate that it is worthy investigating whether these chemicals are useful in the management of vasospasm of aneurysmal subarachnoid hemorrhage.
Alkaloids*
;
Animals
;
Aorta*
;
Brain*
;
Catecholamines
;
Dobutamine
;
Heart Rate
;
Prazosin
;
Propranolol
;
Rats*
;
Subarachnoid Hemorrhage
;
Vasodilation
8.Relationship Between Post-Systolic Motion During Dobutamine Stress Echocardiography and Functional Recovery of Myocardium After Successful Percutaneous Coronary Intervention.
Korean Circulation Journal 2009;39(11):477-481
BACKGROUND AND OBJECTIVES: Doppler myocardial imaging (DMI) has been suggested as a method of quantifying inducible ischemia during dobutamine stress echocardiography (DSE). Post-systolic motion (PSM) detected by DMI is related to peri-infarct ischemia during DSE. We hypothesized that PSM during DSE would predict recovery of dysfunctional myocardium after successful percutaneous coronary intervention (PCI). SUBJECTS AND METHODS: Thirty patients with dysfunctional myocardium in the left anterior descending coronary artery (LAD) territory were divided into two groups according to improvement of wall motion score index (WMSI) in the LAD territory at 6 months after successful PCI of the LAD. DMI was evaluated in the LAD territory during DSE. Fifteen patients showed improved WMSI (1.42+/-0.39) while the other 15 had unchanged WMSI (1.75+/-0.46) 1 month after PCI. Myocardial velocity was measured in the mid-septal, apico-septal, and basal anterior segments of the LAD artery territory. PSM was defined as a positive wave appearing after the curve of systolic ejection had reached the zero line. RESULTS: Although there was no difference between resting PSMs in both groups, PSM during DSE was significantly higher in the improved WMSI group than in the WMSI group where it was unchanged. CONCLUSION: PSM during DSE predicts recovery of dysfunctional myocardium after successful PCI.
Arteries
;
Coronary Vessels
;
Dobutamine
;
Echocardiography, Stress
;
Humans
;
Ischemia
;
Myocardial Stunning
;
Myocardium
;
Percutaneous Coronary Intervention
9.The Accuracy of Aortic Valve Area Determined by Transesophageal Echocardiography using Direct Planimetry According to the Changes of Cardiac Output and Left Ventricular Ejection Fraction.
Seung Won JIN ; Chong Jin KIM ; Hee Youl KIM ; Ji Won PARK ; Doo Soo JEON ; Ho Jung YOUN ; Jun Cheol PARK ; Tai Ho RHO ; Jang Seong CHAE ; Jae Hyung KIM ; Soon Jo HONG ; Kyu Bo CHOI
Korean Circulation Journal 2000;30(8):973-979
> BACKGROUND: The accuracy of flow-related changes in aortic valve area (AVA) determined by the Gorlin formula or the continuity equation remains disputable. However, anatomic AVA can be determined by using by direct planimetry of transesophageal echocardiography (TEE). The purpose of this study was to assess the impact of changes in flow on AVA determined by TEE using direct planimetry. METHOD: Determination of AVA by TEE using direct planimetey was performed intraoperatively under three different hemodynamic conditions - pre-dobutamine (baseline) period, post-dobutamine period, post-CABG period - in 17 CABG patients and cardiac output (CO) with left ventricular ejection fraction (EF) were also determined by TEE simutaneously. The changes in aortic flow were induced by dobutamine infusion. RESULTS: AVA at pre-dobumaine period, post-dobutamine period, and post-CABG period were 2.99+/-0.80 cm2, 3.01+/-0.79 cm2, and 3.01+/-0.80 cm2, respectively. Before dobutamin infusion, CO and EF were 2.01+/-0.64 L/min and 47+/-10%. After dobutamine infusion, CO and EF were 3.03+/-1.05 L/min, 54+/-9% respectively and significantly increased by 54%, 18% than those measured before dobutamine infusion (p<0.01, p<0.01), respectively. After CABG, CO and EF were 3.86+/-1.86 L/min and 58+/-11% and also significantly increased by 98%, 26% than those measured before dobutamine infusion (p<0.01, p<0.01), respectively. However, despite of these significant hemodynamic changes, there were no significant changes in AVA and no significant correlations between these hemodynamic and AVA changes, neither at post-dobutamine period nor post-CABG period. CONCLUSION: The acute changes in CO and EF do not result in significant alterations in the anatomic AVA determined by TEE using direct planimetry. Thus, TEE using direct planimetry could be accurate and useful in the determination of AVA in hemodynamically unstable patient.
Aortic Valve*
;
Cardiac Output*
;
Dobutamine
;
Echocardiography, Transesophageal*
;
Hemodynamics
;
Humans
;
Stroke Volume*
10.The Accuracy of Aortic Valve Area Determined by Transesophageal Echocardiography using Direct Planimetry According to the Changes of Cardiac Output and Left Ventricular Ejection Fraction.
Seung Won JIN ; Chong Jin KIM ; Hee Youl KIM ; Ji Won PARK ; Doo Soo JEON ; Ho Jung YOUN ; Jun Cheol PARK ; Tai Ho RHO ; Jang Seong CHAE ; Jae Hyung KIM ; Soon Jo HONG ; Kyu Bo CHOI
Korean Circulation Journal 2000;30(8):973-979
> BACKGROUND: The accuracy of flow-related changes in aortic valve area (AVA) determined by the Gorlin formula or the continuity equation remains disputable. However, anatomic AVA can be determined by using by direct planimetry of transesophageal echocardiography (TEE). The purpose of this study was to assess the impact of changes in flow on AVA determined by TEE using direct planimetry. METHOD: Determination of AVA by TEE using direct planimetey was performed intraoperatively under three different hemodynamic conditions - pre-dobutamine (baseline) period, post-dobutamine period, post-CABG period - in 17 CABG patients and cardiac output (CO) with left ventricular ejection fraction (EF) were also determined by TEE simutaneously. The changes in aortic flow were induced by dobutamine infusion. RESULTS: AVA at pre-dobumaine period, post-dobutamine period, and post-CABG period were 2.99+/-0.80 cm2, 3.01+/-0.79 cm2, and 3.01+/-0.80 cm2, respectively. Before dobutamin infusion, CO and EF were 2.01+/-0.64 L/min and 47+/-10%. After dobutamine infusion, CO and EF were 3.03+/-1.05 L/min, 54+/-9% respectively and significantly increased by 54%, 18% than those measured before dobutamine infusion (p<0.01, p<0.01), respectively. After CABG, CO and EF were 3.86+/-1.86 L/min and 58+/-11% and also significantly increased by 98%, 26% than those measured before dobutamine infusion (p<0.01, p<0.01), respectively. However, despite of these significant hemodynamic changes, there were no significant changes in AVA and no significant correlations between these hemodynamic and AVA changes, neither at post-dobutamine period nor post-CABG period. CONCLUSION: The acute changes in CO and EF do not result in significant alterations in the anatomic AVA determined by TEE using direct planimetry. Thus, TEE using direct planimetry could be accurate and useful in the determination of AVA in hemodynamically unstable patient.
Aortic Valve*
;
Cardiac Output*
;
Dobutamine
;
Echocardiography, Transesophageal*
;
Hemodynamics
;
Humans
;
Stroke Volume*