Study on 175 patients underwent Roux-en-Y hepatico-jejunostomy on the Y ansa with subcutaneous intestinal extremities because of intrahepatic and extrahepatic stones. There was no postoperative death. Short-term outcomes were good in 64.57%, moderate in 27.2%, and poor in 8.00%. Long-term outcomes were good in 71.95%, moderate in 20.12%, and poor in 7.92%. Treatment for main stone by drain lavage was good in 25.22%, moderate in 28.00% and bad in 45.94%. Treatment for residual stone under image intensifier through intestinal head was good in 31.13%, moderate in 68.17% and bad in 0%. These findings showed that this technique is good in treating postoperative residual and recurrent stones
Gastric Bypass ; Surgery ; Therapeutics

Diabetes mellitus is characterized by hyperglycemic due to impaired insulin secretion or resistance. In our search for anti-diabetic agents, we found that a 70% EtOH extract of Rubus cochinchinensis(Tratt) enhances glucose uptake in 3T3-L1 adipocytes. R. cochinchinensis is predominantly found in East Asia, particularly in Vietnam, Laos, Cambodia, and southern in China. Despite its widespread distribution, there have been few studies on its bioactivity or chemical constituents. In this study, activity-guided fractionation of 70% EtOH extract from the leaves of R. cochinchinensis resulted in the isolation of one new ursane-type glycoside, 3-O-β-acetyl-28-O-β-D-glucopyranosyl-rotundioic acid (1), along with four known compounds (2–5). The structures of these compounds were elucidated using 1D and 2D NMR and HRESIMS data. Notably, compound 4 significantly increased the uptake level of 2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose (2-NBDG) in differentiated 3T3-L1 adipocytes. This study suggests the potential of R. cochinchinensis as a promising medicinal plant for treating diabetes via glucose uptake.