1.Evaluating effect of natrium hyposulphide for treatment of skin diseases due to chromium on experimental rabbits
Journal of Medical and Pharmaceutical Information 2001;3():27-31
The objective of study is to evaluate effects of natrium hyposulphide for treatment the occupational dermatosis due to chromium. 23 rabbits was ulcerated by kalium bichromate 6%, after that they were treated by Hysox 10% solution and Hynax 5% ointment (main composition was natri hyposulphide) and all rabbits were observed generally symptomatically, macro and micro-scopically, and microbiologically. Results showed that : after 2 weeks, the healing rate on the treated rabbit groups was 2.6 and 2.4 times higher than the control group. Authors recommended the further study and the production of this preparation in order to protect the workers exposed to chromium.
Skin Diseases
;
Chromium
2.Carbonoxyd intoxication due to the exhaustion-health situation and prevention
Journal of Practical Medicine 1998;346(3):31-32
Carbonoxyd generated from uncompleted fire of organic products. There were two pathological conditions of carboneoxyd (C) intoxication, including acute intoxication: patients were unconscious after inhaling only 1-2 times and the chronic intoxication was common in which patients experienced headache and nausea... the occupational diseases were increasingly because of the environmental pollution was increasing. This study introduced some preventive solutions such as good waste disposal, reduction of traffic facilities and smoking. It should use the antitoxic mask and examine the health periodically.
Poisoning
;
epidemiology
3.Antibiotic resistance of common pathogenic bacteria isolated from Hai Phong pediatric Hospital in 2003 \ufffd?2004 year period
Sang Ngoc Nguyen ; Hanh Thi Doan ; Thanh Thi Hoang
Journal of Medical and Pharmaceutical Information 2001;6(6):22-27
Background: Bacteria are among the common pathogens in Vietnam and other developing countries. Antibiotics are effective in the treatment, but the antibiotics gradually become ineffective due to drug resistance of bacteria, especially in children..\r\n', u'Objectives: Determine the root cause bacterial infections and often determine the extent of antibiotic resistance of common pathogenic bacteria isolated in Hai Phong pediatric Hospital.\r\n', u'Subjects and method: At Microorganism Department of Hai Phong pediatric Hospital from January 2003 to December 2004, 558 trains of common pathogenic microorganisms were isolated from 0 -15 year old children clinical samples such as: blood, pus, cerebrospinal fluid, urine, stool...These samples of isolated microorganisms were also tested on their sensitiveness to several antibiotics.\r\n', u'Results:Findings showed that the 3 most frequently recognized bacterier out of 11 antibiotic sensitive tested species were: streptococcus pneumoniae (20.61%), neisseria (18.1%), E.coli (15.95%); and the most resisted antibiotics included: Co-trimoxazole, Chloramphenicol and Ampiciline. The staph was resistant to general Chlora, phenicol, Co-trimoxazol, and also sensitive to cefotacim, Amikacin. In the bacillus bacteria tested were resistant blue latex all, only works with Amikacin.\r\n', u'Conclusion: Its also found that every kind of tested bacterium had got various levels of sensitivity to different of antibiotics.\r\n', u'
Anti-Bacterial Agents
;
Bacteria/ microbiology
4.Thoracoscopic splanchnicectomy for control pancreatic pain
Cuong Tan Nguyen ; Tho Anh Bui ; My Tien Doan ; An Thanh Bui
Journal of Surgery 2007;57(3):8-13
Background: Intractable pain is the most distressing symptom in patients suffering from unresectable pancreatic carcinoma and chronic pancreatitis and thoracoscopic splanchnicectomy is an emerging method in the past decade for pain control. Objectives: To evaluate the effectiveness and safety of thoracoscopic splanchnicectomy in controlling pain due to pancreatic diseases. Subjects and method: This descriptive, cross-sectional study was carried out between May 2004 and August 2006, on 29 patients with unresectable pancreatic carcinoma and chronic pancreatitis, treated by thoracoscopic splanchnicectomy. Their subjective pain was assessed by visual analogue scale (VAS). Intra- and post- operative complications and mortality, operative time and hospital length also so have been evaluated. Results: Among 29 patients, there were 21 cases of pancreatic carcinoma (11 males and 10 females) and 8 cases of chronic pancreatitis (100% were male). The average operative time was 133.27 \xb1 8.32 min (range 90-270 min). 27 cases (93.1%) underwent bilateral thoracoscopic splanchnicectomy and 2 cases (6.9%) underwent unilateral procedure. There was no death due to procedure. The mean hospital stay was 4.86 \xb1 0.56 days (range, 1\ufffd?3 days). Pain relief was most effective in the 1st week after operations. Conclusion: Thoracoscopic splanchnicectomy is a safe and effective procedure of treating malignant and benign intractable pancreatic pain. It is needed to study long-term efficacy of pain relief for chronic pancreatitis.
Pancreatic Diseases/ surgery
;
Thoracoscopy
;
5.Some results of malaria parasite species collected from Daknong province and analysis of drug resistance in P.Palciparum by the polymerase chain reaction.
Nhan Hanh Doan ; Duong Van Nguyen ; Thanh Viet Ngo ; Toan Quoc Tran ; Phuong Nhu Vo
Journal of Malaria and parasite diseases Control 2003;0(1):25-30
Background: In many years, National Institute of Malariology, Parasitology and Entomology conducted collection, storage and preservation of malaria parasites species \r\n', u'Objective: to evaluate some results of malaria parasite species collected from Daknong province and analysis of drug resistance in P.Palciparum by the polymerase chain reaction.\r\n', u'Subject and method: Malaria parasite species collected from Daknong province in 2006. Thirty-five isolates were confirmed to be resistant with chloroquin by in vitro test. Polymerase chain reaction-restriction fragment leng polymorphism were used. \r\n', u'Results: 55 Plasmodium jalciparum. 7 Plasmodium vivax. 4 Plasmodium malariae. 1 Plasmodium ovale samples were collected from the malaria patients. A preliminary analysis of drug-resistant mutations in the Plasmodium jalciparum chloroquine resistance transpory (pfcrt) and P Jalciparummulti-drug resistant genes showed that the change of the order of amino-acid of Plasmodium jalciparum was closely correlated to chloroquine resistance in 35 isolates at the mutant allele 76 of pfcrt gene of chloroquine resistant Plasmodiuntjalciparum isolates. \r\n', u'Conclusion: These results contributed to supplement malaria parasite species that were stored in National Institute of Malariology, Parasitology ad Entomology.\r\n', u'
Malaria parasite species
;
polymerase chain reaction
;
P.Palciparum
;
drug resistance
6.Results of treatment for mediastinal tumors by video-assisted thoracoscopic surgery (VATS) in Viet Duc Hospital
Lu Huu Pham ; Huu Cong Nguyen ; Thanh Ngoc Le ; Uoc Huu Nguyen ; Hung Duc Duong ; Hung Quoc Doan
Journal of Surgery 2007;57(5):39-43
Background: Video-assisted thoracoscopic surgery (VATS) is a now new, effective approach in diagnosis and treatment of thoracic diseases. Objective: To summarize and evaluate the results of VATS for mediastinal tumors. Subjects and method: A retrospective study included patients with mediastinal tumors who performed VATS in Viet Duc Hospital from March 2006 to August 2007. The measurements about age, sex, hospital-admitted reasons, tumor\u2019s size and location, outcomes and complications were analysed. Results: There were sixteen patients, included 9 males and 7 females. The patients\ufffd?average age was 35.3 years (ranged from 16 to 72 years). Clinical characteristics of mediastinal tumors were chest pain (11 cases), trouble breathing (4 cases), cough (2 cases). CT scanner detected mediastinal tumors in all patients (16 cases). Pathologically, 15 patients had benign tumors and only one had malignant tumor. The average time for postoperative drainage withdrawal was 3.0625 days (ranged from 2 to 5 days). The average time of hospital stay was 5 days (ranged from 3 to 11 days). There was no postoperative complication. Conclusion: VATS for mediastinal tumors obtained good outcomes. This was a selective method with many advantages for mediastinal tumors.
Mediastinal Neoplasms/surgery
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Thoracic Surgery
;
Video-Assisted
;
7.Resistant to insecticides of three mosquito species: Aedes Aegypti, Culex quinquefasciatus and culex tritaenyorhynchus in Ha Noi
Khoa Thi Pham ; Phong Ba Nguyen ; Ha Thanh Pham ; Bien Thi Vu ; Trang Thi Thu Nguyen ; Khiet Minh Doan
Journal of Malaria and parasite diseases Control 2003;0(1):31-36
Background: Currently, tracking, monitoring insecticide resistance of mosquitoes transmitting disease is an urgent need.\r\n', u'Objectives: To evaluate resistance to insecticide of three mosquito species: Aedes Aegypti, Culex quinquefasciatus and culex tritaenyorhynchus in Ha Noi\r\n', u'Subject and method: Aedes Aegypti, Culex quinquefasciatus culex tritaenyorhynchus mosquito species was collected from some districts of Ha Noi city. These mosquito species was tested sensitivity with 4 insecticides: permethrin 0.75%, lambda-cyhalothrin 0.05%, alpha-cypermethrin 30mg/m2 and DDT 4.0%.\r\n', u'Results: Three main vectors of Dengue fever, Japanese Encephalic and Filariasis mosquitoes were found in a very high density in some areas of Ha Noi City. Aedes aegypti mosquitoes in the districts of Thanh Xuan (TX), Dong Da (DD) and Hoang Mai (HM) was found highly resistant to permethrin, alpha - cypermethrin, lambda - cyhalothrin and DDT with the mortalities rates of 51 % (TX) and 59%(DD); 70%(HM); 90%, 82% and 96%; 74%, 54% and 59%; 1 %, 8% and 32%, respectively. \r\n', u'Culex tritaenyorhynchus was found also highly resistant to permethrin with the mortality rate of 29%, alphacypermethrin - 18%, lambdacyhalothrin - only 3% and DDT x36%. Culex quinquefasciatus was found also highly resistant to those insecticides. \r\n', u'Conclusion: Other insecticides should choose to replace the chemicals used in this experiment to control, kill mosquitoes when epidemics occur.\r\n', u'
Insecticides
;
resistance
;
Aedes Aegypti
;
Culex quinquefasciatus
;
culex tritaenyorhynchus
8.Characteristics of the antibiotic resistance gene of S.pneumoniae isolated from nasopharyngeal swab of the pneumonia patients in Ha Noi
Anh Duc Nguyen ; Huong Le Thanh Phan ; Anh Hien Nguyen ; Khanh Cong Nguyen ; Thi Thi Ngo ; Phuong Mai Doan ; Tsuyoshi Nagatake ; Hiroshi Watanabe ; Kazunori Oishi
Journal of Preventive Medicine 2007;17(4):51-56
Background: Acute lower respiratory tract infection, mainly pneumonia, were the main reasons cause death for children under 5 years old. Objectives: Determine the isolated rate of bacteria inpatients under 5 years old with acute lower respiratory tract infection in Ha Noi and antibiotic resistance of pneumococcal isolated form patients. Subjects and method: Patients under 5 years old with acute lower respiratory tract infection in National hospital of pediatrics and Bach Mai hospital from 01/2002. Using quantitative culturedand PCR method. Results: Out of total 164 patients with lower respiratory tract infection, there were 91 diagnosed pneumonia by chest X-ray, 73 cases of acute bronchitis. 73,6% of the pneumococcal isolated were penicillin resistance (gPRSP) with different genes such as pbp 1a+2x+ab. Most of the S.pneumoniae strains were serotype 19F or 23F. There were no statistic differences by comparison charactersistics of weight, vessel, subclinical symptoms such as: dissolved oxygen level (S\xac\xacp\xac\xac\xac\xacO\xac2\xac), the amount of leucocyte in blood. However, temperature of pneumonia patients was higher than bronchitis patients, breathing of pneumonia patients was also faster than bronchitis patients. Isolated bacteria with amount \ufffd?106 cfu/ml was H.influenzae, S.pneumoniae and Moraxell catarrhalis in pneumonia group, bronchitis group was 28,8% and control group was 17,1%. Conclusion: Penicillin, erythoromycin and co-trimoxazole resistance rate of S.pneumoniaein patients with acute lower respiratory tract infection was high. Quantitative cultured method has prognostic value in diagnosis pneumonia.
Genes
;
MDR/ drug effects
;
immunology
;
Streptococcus pneumoniae/ growth &
;
development
;
Anti-Bacterial Agents
9.Assessing the emergency situation for peripheral vascular wounds/trauma in Viet Duc Hospital from 2004 to 2006
Uoc Huu Nguyen ; Nghia Dinh Che ; Hung Duc Duong ; Hung Quoc Doan ; Huu Cong Nguyen ; Lu Huu Pham ; Tien Anh Do ; Thanh Ngoc Le
Journal of Surgery 2007;4(57):12-19
Background: peripheral vascular wounds/trauma is a severe type of surgical emergency, the increasing rate due to the rapid increase of traffic, labor and living accidents. Subjectives and Method: retrospective study, all patients with peripheral vascular wounds/traumas (alone or combination in multiple trauma) were emergency operated at Viet Duc Hospital from January 2004 to June 2006. Results: A total of 310 patients with peripheral vascular injuries in the study, of which accounted for 62.3% of injury, trauma group accounted for 37.7%. The mean age of 30. In first aid, pressed tape accounted for high rate (71.5%). Rate of popliteal vascular trauma due to fractures around the knee accounted for 65.5%, the rate of brachial vascular trauma with fractures around the elbow was 50%. Rate of late diagnosis of arterial trauma was 14.6%, higher than the arterial wounds (2.6%). The rate of ultrasound for forelimbs - where vessels were many wounds, was lower than that for hindlimbs - where vessels were many traumas (44% vs 67.9%). For vascular wounds, more directly vascular connection and more intervention on veins, whereas, for arterial trauma, more vascular graft. Rate of complications was low (7.4%), with no deaths. Conclusions: Overall, the results of emergency surgery for peripheral vascular wounds/trauma were well. No cases was death from vascular lesions, rate of complications was low.
Blood Vessels/ injuries
;
Emergencies
;
10.Distribution Status of Hybrid Types in Large Liver Flukes, Fasciola Species (Digenea: Fasciolidae), from Ruminants and Humans in Vietnam
Thi Bich Nga NGUYEN ; Nguyen VAN DE ; Thi Kim Lan NGUYEN ; Huynh Hong QUANG ; Huong Thi Thanh DOAN ; Takeshi AGATSUMA ; Thanh Hoa LE
The Korean Journal of Parasitology 2018;56(5):453-461
The aim of this study is to delineate ‘admixed hybrid’ and ‘introgressive’ Fasciola genotypes present in the Fasciola population in Vietnam. Adult liver flukes collected from ruminants in 18 Provinces were morphologically sorted out by naked eyes for small (S), medium (M) and large (L) body shapes; and human samples (n=14) from patients. Nuclear ribosomal (rDNA) ITS1 and ITS2, and mitochondrial (mtDNA) nad1 markers were used for determination of their genetic status. Total 4,725 worm samples of ruminants were tentatively classified by their size: 6% (n=284) small (S)-, 13% (n=614) medium (M)-, and 81% (n=3,827) large (L)-forms. All the representative (n=120, as 40 each group) and 14 human specimens, possessed maternal mtDNA of only F. gigantica and none of F. hepatica. Paternally, all (100%) of the L-(n=40) and 77.5% (n=31) of the M-flukes had single F. gigantica rDNA indicating ‘pure’ F. gigantica. A majority (90%, n=36) of the S- and 15% (n=6) of the M-worms had single F. hepatica rDNA, indicating their introgressive; the rest (10%, n=4) of the S- and 7.5% (n=3) of the M-flukes had mixture of both F. gigantica and F. hepatica rDNAs, confirming their admixed hybrid genetic status. Fourteen human samples revealed 9 (64%) of pure F. gigantica, 3 (22%) of introgressive and 2 (14%) of admixed hybrid Fasciola spp. By the present study, it was confirmed that the small worms, which are morphologically identical with F. hepatica, are admixed and/or introgressive hybrids of Fasciola spp., and able to be the pathogens of human fascioliasis.
Adult
;
DNA, Mitochondrial
;
DNA, Ribosomal
;
Fasciola hepatica
;
Fasciola
;
Fascioliasis
;
Genotype
;
Humans
;
Liver
;
Ranunculaceae
;
Ruminants
;
Vietnam