1.Studies on the production and application of monoclonal antibodies against human gastrointestinal tumor cell lines(I).
Korean Journal of Immunology 1991;13(2):201-214
No abstract available.
Antibodies, Monoclonal*
;
Humans*
2.Distribution of the deposits of immunoglobulin,fibrinogen and fibronectin in psoriatic Lesions.
Korean Journal of Dermatology 1993;31(1):76-82
This study was conducted to observe immunological abnormalities, vscular changes and abnormal maturation, pathway of keratinocyte in the psoriasis, by comparing drposits of IgG, fibrinogen(FG) and fibronectin(FN) in the invnlved and uninvolved skin of 19 psoriaics before treatment, the involved skin of 12 among the above patients after treatment, and the skin of 8 normal controls. The study was carried out by using direct immunofluorescence technique with anti-IpG, anti-FG, anti-FN antibodies. The results are summarized as follows: 1. In the uninvolved skin of 19 psoriatics before treatment, no depasition of IgG was observed while deposition of FG was present at the dermo-epidermal junction in 5.3% of the patients and dermis(10.5 %). Deposition of FN was found at the dermo-epidermal junction(52%), papillary dermis(57.9%) and dermal blood vessels(52.6%). 2. In the involved skin of 19 psoriatics before treatment, deposition of IgG was observed in the horny layer in 84.2% of the patients, upper epidermis(15.8%) and depositicin of FG was present in the horny layer(52.6%), upper epidermi(63.1%), dermo-epidermal junction(15.8%), upper dermis(15.8%) and dermal blood vessels(5.3%). Leposition of FN was found in the horny ayer(26.3%), upper epidermis (36.8%), dermo-epidermal junction(78.9%), upper dermis(89.5%) and ermal blood vessels(68.4%). 3. In the involved skin of 12 psoriatics after treatment, IgG was wealily deposited in the horny layer in 16.7% of the patients and deposition of FG was observed in the horny layer(8.3%), upper epidermis (16.7%), dermo-epidermal junction(8.3%) and dermis(8.3%). Deposition of FN was found in the upper epiderrnis(8.3%), dermo-epiderrnal junction(58.3%), dermis(66.%) and dermal blood vessels (33.3%) 4. In the normal skin of 8 control subjects, no deposition of IgG and, FG was observed while deposition of FN was found at the inummo-epidermal junction in 37.5% of the persons, upper dermis(25%) and dermal blood vessels(12.5%)
Antibodies
;
Blood Vessels
;
Epidermis
;
Fibrinogen
;
Fibronectins*
;
Fluorescent Antibody Technique, Direct
;
Humans
;
Immunoglobulin G
;
Immunoglobulins
;
Keratinocytes
;
Psoriasis
;
Skin
3.A Case of Idiopathic Calcinosis of the Scrotum.
Do Won KIM ; In Ju KIM ; Sang Lip CHUNG
Korean Journal of Dermatology 1982;20(5):719-725
Idiopathic calcinosis of the scrotum consists of multiple asymptomatic nodules of the scrotum without any underlying disease. We presented a case of idiopathic calcinosis of the scrotum and compared it with other reported cases in Korea, A 47-year-old farmer had slowly growing, asymptomatic, hard scrotal nodules which were 1cm in diameter and 6 in number for about twenty years. KUB X-ray film showed two radiopaque densities on the scrotal area. Histopathological finding revealed amorphous, basaphilic masses with acicular clefts which were confirmed as calcification in Von Kossa stain and surrounding foreign body granulomatous inflammatory reaction.
Calcinosis*
;
Foreign Bodies
;
Humans
;
Korea
;
Middle Aged
;
Scrotum*
;
X-Ray Film
4.Mineral Water Investigation on 10 Area in Seoul.
Hyung Suk KIM ; Do Suh KOO ; Yang Won PARK
Korean Journal of Preventive Medicine 1977;10(1):59-61
We are calling the erupting ground water as drug water or mineral water in Korea and thinking those water and food making water. Authors tried to investigate the evidence of contamination by user on the 10 erupting ground water and gained following results: 1. All of the mineral waters on 10 area in Seoul were unfittable to drinking water standard. 2. In the view of the bacteriology 80% were contaminated by coliform group. 3. The highest value of the free carbon dioxide contents were 652.96 ppm at Sam Sun Mineral Water.
Bacteriology
;
Carbon Dioxide
;
Drinking Water
;
Groundwater
;
Korea
;
Mineral Waters*
;
Seoul*
;
Solar System
;
Thinking
;
Water
5.Effect of administration of etretinate and fish oil on plasma cholesterol levels in rats.
Kuk Hyeong LEE ; Do Won KIM ; Jae Bok JUN
Korean Journal of Dermatology 1991;29(2):167-173
The authors studied the plasma cholesterol levels in 39 rats (Sprague-Dawley) after 4 weeks administration of etretinate and/or fish oil. The study groups were as follows.'13 rats recieved etretinate only;13, fish oil only;13, both ertetinate and fish oil. Cholesterol levels were determined by standard enzymatic methodology. The results were as follows. Tot,al-cholesterol levels in rats following administration of ertetinate only were increased(p<0.05), but the levels in rats receiving fish oil only and both etretinate and fish oil were markedly decreased(p<0.01). HDL-cholesterol levels in rats following administration of fish oil and both etretinate and fish oil were decreased(p<0.01). The ratio of HDL-cholesterol to total-cholesterol in rats receiving fish oil only and both etretinate and fish oil were increased(p<0.05) because of markedly decreased total-cholesterol levels.
Acitretin*
;
Animals
;
Cholesterol*
;
Etretinate*
;
Plasma*
;
Rats*
6.The Present Status of Venereal Disease Morbidity for prostitutes of Foreign Soldiers.
Do Young CHOI ; Sang Lip CHUNG ; Sang Won KIM
Korean Journal of Dermatology 1979;17(5):329-337
Two hundreds and ninty-four prostitutes of foreign soldiers of K2 area in Taegu were investigated for their general circumtances, clinical and bacteriological studys from Mar. 1978 to May 1979. The results were as foIIows: The age group of 20-24 year-old constituted highest proportion at the level of about 53.4% Averge age of total casea was about 26.2. The propartion of those who were more than 35 occupied about 7.2%. The positive rate of Cram negative displococci (GND) on dirert smers showed highest in December and, January and lowest in-April. Wcekly distribution shwed a higher in second and fourth week. Nongonococcal infect.ions occupied about 45.4%. and total raes. The causative oanism. were niostly Gram negative and Gram positive bacilli. The mothly spells and perons with gonorrhea priod prevaIence rate showed a higher rate in Becember, January and July. The prevalence ratio of gonorrhea and syphilis was 13: 1. The examined cases occupied about 34.3, during first 2 month is after registration. The seasoal vari tion of registrators and cancellators were both most in winter. The positive rate of GND was ahout 53.1% in new comers less than two month-examinations after regiatration. Cervical erosion or chronic cervicitis .;howed about 44.8% among the examined 96% cases. Gonococci were isoIated about 25.6% among the ones with cervical lesions on Thayer-Martin media. On the other hand, the ones without lesions were about 11.3% comparatively. Syphilis period prevalence rate was about 8. 5 A. The titers of VDRL slide test were low (1; 8 or less). Two-thirds of positive cases of GND were treated by penicillin, although tetracycline and spectinomycin were also used in a few cases. The penicillin hypersensitivity sho- wed positive results in 9.7% of all treated cases.
Daegu
;
Gonorrhea
;
Hand
;
Humans
;
Hypersensitivity
;
Military Personnel*
;
Penicillins
;
Prevalence
;
Sex Workers*
;
Sexually Transmitted Diseases*
;
Spectinomycin
;
Syphilis
;
Tetracycline
;
Uterine Cervicitis
7.A Case of Sea Urchin Granuloma.
Do Won KIM ; Su Hee OH ; Sang Lip CHUNG
Korean Journal of Dermatology 1983;21(4):445-449
Sea urchin granuloma is a rare skin disorder, considered to be allergic or foreign body reaction caused by stick of spines of sea urchin. However, detection of the spine in the granuloma is quite difficult. A 27 year-old marine was seen with several asymptomatic hard nodules on the dorsum of hands, fingers, forearrns and knees at the injured site of the spines after a latent period of 6 rnonths. Histolagical examination revealed dermal granulomatous inflamation with hyperkeratotic and acanthotic epidermis. On examination with polarized microscopy, sea urchin spines in the granuloma were seen as bright white fragments in the dark field. Those nodules were regressed with intralesional injection of triamcinoIone.
Adult
;
Epidermis
;
Fingers
;
Foreign-Body Reaction
;
Granuloma*
;
Hand
;
Humans
;
Injections, Intralesional
;
Knee
;
Microscopy
;
Sea Urchins*
;
Skin
;
Spine
9.Clinical pictures of somatization disorder.
Ho Chan KIM ; Dong Won OH ; Jeong Soo DO
Journal of Korean Neuropsychiatric Association 1992;31(2):240-251
No abstract available.
Somatoform Disorders*
10.Mating Study of Microsporum canis Isolated in Korea.
Soon Bong SUH ; Do Won KIM ; Jae Bok JUN
Korean Journal of Dermatology 1983;21(5):557-561
A total of 135 strains of M canis, composed of 1R4 from the patients and 1 from an infected pet cat, were crossed with the 2 tester strains of eVannizzia otae VUT 77054 "/" and VUT 77055 "-" supplied by Dr. A. Hasegawa. These 134 human strains were originated from 77 casea of tinea capitis, 20 of tinea faciei and 37 of tinea corporis from Taegu city, Kyungpook and neighboring provinces during the period from December 1975 to August 1982. Out of 134 hurnan isolates, 112 (83. 6%) were of "-" mating type of N. otae and 22 (16.4%) were nonreactive. None were compatible with the + mating type. One strain from a pet cat proved also to be of type. The majority of the tested strains were revealed to be sexually degenerated.
Animals
;
Cats
;
Daegu
;
Gyeongsangbuk-do
;
Humans
;
Korea*
;
Microsporum*
;
Tinea
;
Tinea Capitis