We evaluated the effectiveness of photoastigmatic refractive Keratectomy(PARK) by excimer laser on patients with compound myopic astigmatism. Spherocylindrical PARK was performed on 181 myopic eyes with astigmatism(mean spherical equivalent : -6.61 D, range : -1.88~-14.5 D) using the visx excimer laser. The eyes were divided into three groups according to the amount of desired astigmatic correction : Group 1(-0.5~-1.0 D), Group 2(-1.25~3.0 D), and Group 3(-3.25~-5.5 D). Patients were followed up for 6 months. Uncorrected visual acuity at postoperative 6 month, was 0.80+/-0.27 in Group 1, 0.79+/-0.19 and 0.71+/-0.21bin Group 2 and 3 respectively. The mean spherical equivalent refraction was -0.24 D 6 months after PARK. Mean astigmatism was reduced from preoperative -0.85+/-0.51 D to postoperative -0.34+/-0.38 D in Group 1, from -2.08+/-0.65 D to -0.43+/-0.64 D and from -4.42+/-0.63 D to -1.23+/-1.25 D in Group 2 and 3 respectively. We also analyzed the angle of error, magnitude of error, index of success, and coefficient of afjustment by vector analysis. No significant complications were observed during the follow-up period. These results show that PARK by excimer laser was effective in correction of astigmatism. The effect of astigmatic correction in Group 2 and 3 were better than that of Group 1. Group 1 showed overcorrected tendency and Group 2 and 3 showed undercorrected tendency.
Astigmatism ; Follow-Up Studies ; Humans ; Lasers, Excimer* ; Visual Acuity

We evaluated the effectiveness of photoastigmatic refractive Keratectomy(PARK) by excimer laser on patients with compound myopic astigmatism. Spherocylindrical PARK was performed on 181 myopic eyes with astigmatism(mean spherical equivalent : -6.61 D, range : -1.88~-14.5 D) using the visx excimer laser. The eyes were divided into three groups according to the amount of desired astigmatic correction : Group 1(-0.5~-1.0 D), Group 2(-1.25~3.0 D), and Group 3(-3.25~-5.5 D). Patients were followed up for 6 months. Uncorrected visual acuity at postoperative 6 month, was 0.80+/-0.27 in Group 1, 0.79+/-0.19 and 0.71+/-0.21bin Group 2 and 3 respectively. The mean spherical equivalent refraction was -0.24 D 6 months after PARK. Mean astigmatism was reduced from preoperative -0.85+/-0.51 D to postoperative -0.34+/-0.38 D in Group 1, from -2.08+/-0.65 D to -0.43+/-0.64 D and from -4.42+/-0.63 D to -1.23+/-1.25 D in Group 2 and 3 respectively. We also analyzed the angle of error, magnitude of error, index of success, and coefficient of afjustment by vector analysis. No significant complications were observed during the follow-up period. These results show that PARK by excimer laser was effective in correction of astigmatism. The effect of astigmatic correction in Group 2 and 3 were better than that of Group 1. Group 1 showed overcorrected tendency and Group 2 and 3 showed undercorrected tendency.
Astigmatism ; Follow-Up Studies ; Humans ; Lasers, Excimer* ; Visual Acuity

Although there are various methods of operative treatment for hony mallet finger, the operative technique is not so easy and complications such as joint stiffness, sott tissue prohlems, infection, change of nail shape and arthrosis are common. The authors performed operations for 26 cases of hony mallet fingers, fixing the hony frapment by Kirschner wire, pull-out wire suture and miniscrew respectively, from Jan. l988 to Jun. l996. The results were as follows. l. According to Niechajev's classification. there were 3 cases of type B, 7 cases of type C, l4 cases of type D, and 2 cases of type E. And 11 cases were accompanied hy crushing injury. 2. Involved fingers were third finger in 11cases, fit'th finger in 7 cases, fourth finger in 5 cases, second finger in 2 cases. and thumb in I case. 3. The hony mallet finger was caused hy occupational injury in l6 cases, direct blow in 7 cases and sports injury in 3 cases. 4. The fractured fragment was fixed hy Kirschner wire in 9 cases, by pull-out suture in 9 cases and by miniscrew in 8 cases. 5. The results were evaluated hy Kanies scale. Sixteen cases had satisfactory results. Seven cases (87.5%) were satisfactory in miniscrew fixations. 5 cascs (55.6%) in pull-out wire suture methocls and 2 cases (22.2%) in Kirschner wire tixations. 6. The complications were joint incongruity in 4 cases, dorsal prominece in 6 cases, painful limitation of motion in 2 cases which were treated by arthrodesis, pin site infection in 2 cases and hreakage of wire suture in 1 case. 7. The miniscrew fixation offered relatively firm fixation, low complication rate, and good results. so it can be considered as one of the good methods of treatment for hony mallet finger.
Arthrodesis ; Athletic Injuries ; Classification ; Fingers* ; Joints ; Occupational Injuries ; Sutures ; Thumb

Basaloid squamous cell carcinoma (BSCC), an uncommon tumor with predilection for the upper aerodigestive tract, is a distinct variant of squamous cell carcinoma, because of its unique histological features and ominous clinical behavior. Basaloid squamous cell carcinoma is a high-grade variant of squamous cell carcinoma. Reports subsequent to its initial description in 1986 by Wain et al. have confirmed that the head and neck region is the most frequently involved region, with majority of the cases arising in the supraglottic larynx, hypopharynx, tonsil and base of tongue. Other head and neck sites include the palate, buccal cavity, floor of mouth, nasopharynx, trachea, and sinonasal tract. BSCC is not limited to the head and neck region but has also been described in the esophagus, lung, thymus, anus and cervix among other sites. We experienced and treated a case of BSCC extended to the temporal bone with characteristic histopathologic and immunologic features. Therefore, we report here the rare case of BSCC invading the temporal bone with literature.
Anal Canal ; Carcinoma, Squamous Cell* ; Cervix Uteri ; Esophagus ; Female ; Head ; Hypopharynx ; Larynx ; Lung ; Mouth Floor ; Nasopharynx ; Neck ; Palate ; Palatine Tonsil ; Temporal Bone* ; Thymus Gland ; Tongue ; Trachea

No abstract available.
Ossicular Prosthesis*

BACKGROUND: Type I collagen is a major component of extracellular cellular matrix in tissue. It is synthesized by human skin fibroblasts. However, synthesis of type I collagen is markedly-decreased in senescent fibroblasts. In the cell cycle, the hallmark of senescent fibroblasts is a permanent G1 phase arrest. However it is largely unknown whether the expression of type I collagen protein is decreased by the G1 phase arrest in human skin fibroblasts after UVB irradiation, serum starvation, or mimosine, an inducer of the G1 phase arrest treatment. OBJECTIVE: The purpose of this study was to investigate the expression of type I collagen protein in G1 phase- arrested human skin fibroblasts after UVB irradiation, serum starvation, and mimosine treatment. METHODS: To induce G1 phase arrest in the cell cycle, human skin fibroblasts were irradiated by UVB (100, 200, 300 mJ/cm(2)), subjected to serum starvation for 5 days, or mimosine treatment (50, 100, 200 uM). The expressions of type I collagen protein were analyzed by Western blot analysis. RESULTS: The G1 phase of cell populations were increased by a dose or time-dependent manner with UVB irradiation, serum starvation, and mimosine-treated human skin fibroblasts. The expression of type I collagen protein was markedly-decreased by UVB, serum starvation, and mimosine treatment. CONCLUSION: The expression of type I collagen protein in human skin fibroblasts is decreased by UVB irradiation, serum starvation, and mimosine treatment through induction of G1 phase cell cycle arrest.
Blotting, Western ; Cell Cycle ; Cell Cycle Checkpoints ; Collagen Type I* ; Down-Regulation* ; Fibroblasts* ; G1 Phase ; G1 Phase Cell Cycle Checkpoints* ; Gene Expression* ; Humans* ; Mimosine ; Skin* ; Starvation

No abstract available.

No abstract available.

No abstract available.
Adolescent* ; Humans ; Male* ; Psoriasis*

No abstract available.