It is widely blieved that the new bone formation is provoked by fine electrical stress to bone. There have been maay experimental studies that showed much efforts to define these small amounts of electricity, and these fine electricities are being used in the orthopedic field for the treatment of various fractures, nonunions and pseudsrthrosia The auther has checked the electrical potentials changing in the course of fractvre hesling in rabbits femur. Comparing these data with that of the normal control group, the following results were obtained. 1. In the normal rabbit's femur the electrical potentisl was 13.6mV less on the concave side than on the convex side. This finding can be explained by the existence of stress generated potential or piexoelectricity. 2. Electrcal potentials on the fractured femoral sites were lowered significantly from that of the control group. So auther could confirm the existence of bioelectrical generated by increased electrical activity of the living bone. 3. The electrical potential of the fractured femoral site has been decreased 50% and 20% as low as that of the normal site at 8 weeks respectively. It is expected that these lowered electrical potentials may become dose to the normal values when the changed metabolic process due to the fractured bone is no longer functioning and it is believed to take human 2 years to get the normal value.
Electricity ; Femur ; Fracture Healing ; Humans ; Metabolism ; Orthopedics ; Osteogenesis ; Rabbits ; Reference Values

No abstract available.

Morphological changes of the kidney after ESWL in 130 patients are analyzed with CT at Dept. of Urology, Chung-Ang University Hospital from March 1987 to May 1987. Of 130 patients, 9 patients(6.9%) showed renal hematoma. Among 9 patients, 5 patients (3.8%) had subcapsular hematoma and 4 patients(3.1%) had parenchymal hematoma. We analyzed these 9 patients radiologically and clinically. These hematoma were clinically insignificant and self-limited in all cases. So ESWL can be regarded as a safe modality for treatment of the renal and ureteral calculi.
Hematoma* ; Humans ; Kidney ; Shock* ; Ureteral Calculi ; Urology

The purpose of this study was to evaluate the effects of pre-incisional lidocaine injected into tonsils with low-dose fentanyl supplementation on the cardiovascular stability and on the developrnent of intraoperative arrhythmia for pediatric adenotonsillectomy under general anesthesia. Thirty-three pediatric patients undergoing adenotonsillectomy under general anesthesia were randomly aUocated to one of the 3 groups according to the medications used for anesthesia.; 1) N2-O2-halothane only, 2) N2-O2-halothane plus pre-incisional infiltration of 2% lidocaine and 1: 80,000 epinephrine into tonsils after tracheal intubation, 3) N2-O2-halothane plus 2 mcg/kg intravenous fentanyl before induction of anesthesia plus pre-incisional infiltration of 2% lidocaine and 1: 80,000 epinephrine into tonsils after tracheal intubation. All Patients received (0.01/kg+0.15) mg atropine sulfate and 5 mg/kg thipental sodium and inhaled N2-O2-halothane (2 L-2 L-2 vol%) for induction. Tracheal intubation was facilitated with 1.5 mg/kg succinylcholine. After tracheal intubation, anesthesia was maintained with 5% N2O in oxygen and 1 vo1% halothane. 0.1 mg/kg vecuronium was used for myorelaxation. SBP, DBP, MAP, and HR were measured at 1 min, 3 min after intubation, immediately after the incision of tonsils, and after the position change of endotracheal tube. ECG changes were also observed during surgery. After surgery, the degree of irritability and the recovery time were evaluated in all patients in the recovery room. The results were as follows; 1) In Gmup 3, the increases of systolic BP at 3 min and HR at 1 min after tracheal intubation were significantly lower than other two groups. 2) The maximum value of intraoperative systolic BP was the highest in Group 1, followed by Group 2, and then Group 3. 3) The peak intraoperative HR attained was the lowest in Group 3. Difference between Group 1 and 2 was not significant. 4) No cardiac arrhythmia was present in Group 3, 5) The degree of postaperative imtabiTity was the lowest in Gmup 3 and the highest in Group 1. In conclusion, these results indicate that supplementation of low-dose fentanyl and preincisional infiltration of tonsils with lidocaine for pediatric adenotosillectomy under genral anesthesia is useful in reducing cardiovascular instability during tracheal intubation and surgery as well as the incidence of intraoperative cardiac arrhythmia, and postoperative pain.
Anesthesia ; Anesthesia, General ; Arrhythmias, Cardiac ; Atropine ; Blood Pressure* ; Electrocardiography ; Epinephrine ; Fentanyl* ; Halothane ; Heart Rate* ; Heart* ; Humans ; Incidence ; Intubation ; Lidocaine* ; Oxygen ; Pain, Postoperative ; Palatine Tonsil* ; Recovery Room ; Sodium ; Succinylcholine ; Vecuronium Bromide

BACKGROUND: Dexmedetomidine has a sedative analgesic property without respiratory depression. This study evaluated the efficacy of dexmedetomidine as an appropriate sedative drug for monitored anesthesia care (MAC) in outpatients undergoing cataract surgery on both eyes compared with combination of propofol and alfentanil. METHODS: Thirty-one eligible patients were randomly divided into two groups on the first operation day. Dexmedetomidine was administered in group D at 0.6 microg/kg/h, and propofol and alfentanil was infused concomitantly in group P at a rate of 2 mg/kg/h and 20 microg/kg/h, respectively. Sedation was titrated at Ramsay sedation score 3. Iowa satisfaction with anesthesia scale (ISAS) of the patients was evaluated postoperatively. Systolic blood pressure (SBP), heart rate (HR), respiration rate (RR), and peripheral oxygen saturation (SpO2) were recorded throughout the surgery. For the second operation, the group assignments were exchanged. RESULTS: Postoperative ISAS was 50.3 (6.2) in group D and 42.7 (8.7) in group P, which was statistically significant (P < 0.001). SBP was significantly lower in group D compared with group P from the beginning of the operation. HR, RR, and SpO2 were comparable between the two groups. There were 8 cases (25.8%) of hypertension in group P, and 1 case (3.2%) in group D (P < 0.05). In contrast, 1 case (3.2%) of hypotension and 1 case (3.2%) of bradycardia occurred in group D. CONCLUSIONS: Compared with the combined use of propofol and alfentanil, dexmedetomidine could be used appropriately for MAC in cataract surgery with better satisfaction from the patients and a more stable cardiovascular state.
Alfentanil ; Anesthesia ; Blood Pressure ; Bradycardia ; Cataract ; Dexmedetomidine ; Eye ; Heart Rate ; Humans ; Hypertension ; Hypotension ; Iowa ; Outpatients ; Oxygen ; Propofol ; Respiratory Insufficiency ; Respiratory Rate

The pathogenesis of thrombocytopenia in the gestational thrombocytopenia is not understood.This syndrome may represent either the de novo development of ITP or an accelerationof the physiologic pattern of increased platelet destruction that occurs during gestation. Thisdisorder is not easily distinguishable from classical ITP. However, the recognition and diagnosisof this syndrome is important because infants born to individuals with gestational thrombocytopeniaappear to have a markedly reduced risk of developing thrombocytopenia when comparedto infants born to patients with a history of ITP antedating pregnancy. We represent a caseof delivery in severe gestational thrombocytopenia with brief review of the literature.
Blood Platelets ; Humans ; Infant ; Pregnancy ; Thrombocytopenia*

Unlike the small cell carcinoma of the lung, much remains to be discovered about the natural history and of optimal therapy of primary small cell carcinoma of the pancreas. We experienced a case of a primary small cell carcinoma of pancreas with both adrenal metastasis. The patient was a seventy-year old woman who had complained of right upper quadrant abdominal pain for 1 month. Chest x-ray revealed no abnormality. Abdominal CT scan showed a non-enhancing low density mass in uncinate process of pancreas, retropancreatic lymphadenopathy and well defined masses in both adrenal gland. CT-guided biopsy of pancreas showed small cell carcinoma. Herein, we report a case of primary small cell carcinoma of the pancreas with both adrenal metastasis and review the literature.
Abdominal Pain ; Adrenal Glands ; Biopsy ; Carcinoma, Small Cell* ; Female ; Humans ; Lung ; Lymphatic Diseases ; Natural History ; Neoplasm Metastasis ; Pancreas* ; Thorax ; Tomography, X-Ray Computed

Most osteosarcomas arise spontaneously, but rarely they may be secondary to other benign osseous conditions and may occur following irradiation. Postradiation sarcoma of bone is approximately 5.5 percent of all osteogenic sarcoma. Diagnosis is possible when a sarcoma arising after long latent period(more than 3 years) in irradiated bone and the bone is normal or benign osseous lesion at the time of irradiation. The spontaneously arising osteogenic sarcomas are distribute mainly in the knee region, but postradiation sarcoma arise in any bones, such as long bone of the extremity, pelvic bone, vertebra, craniofacial bone and shoulder girdle bone. Recently we experienced a case of postradiation osteosarcoma of the pelvic bone who received radiation therapy for carcinoma of the uterine cervix 20 years ago.
Cervix Uteri ; Diagnosis ; Extremities ; Female ; Knee ; Osteosarcoma* ; Pelvic Bones* ; Sarcoma ; Shoulder ; Spine

BACKROUND: Polymorphism of glycoprotein IIIa on human platelets is one of the factors in alloimmunization that causes neonatal alloimmune thrombocytopenia (NATP), and the granulocyte antigens NA1 and NA2 are often targets of granulocytes antibodies causing neonatal alloimmune neutropenia (NANP). Currently, serotyping relies on the properties of the typing sera or antibodies and technique used. Genotyping circumvents the problems associated with serotyping. METHODS: The genomic DNA of 200 unrelated pregnant women admitted to Taegu Fatima Hospital was typed for three platelet glycoprotein IIIa-specific antigens (HPA-1, HPA-4, and HPA-6w) and granulocyte antigens (NA1 and NA2). Allele specific amplification test using primer designed to study HPA-1 and HPA-4, restriction fragment length polymorphism to study HPA-6w, and sequence specific primers for NA1 and NA2 were used for genotyping. RESULTS: The genotype frequencies were HPA-1(a+b-) 100%, HPA-4 (a+b-) 97.5%, HPA-4(a+b+) 2.5%, HPA-6w(a+b-) 97%, and HPA-6w(a+b+) 3%. These frequencies are similar to Japanese but different from Caucasian. The gene frequencies of NA1 and NA2 were 0.56 and 0.44 respectively. There are no cases of alloimmune thrombocytopenia and neutropenia in newborns from the 200 studied women. CONCLUSIONS: The differences in genotype frequencies among platelet glycoprotein IIIa-specific antigens and in the gene frequencies of NA in Koreans are shown as compared with other ethnic groups. Therefore it is needed to find the proper screening target antigens and antibodies for Korean NATP and NANP patients.
Alleles ; Antibodies ; Antigens, Human Platelet ; Asian Continental Ancestry Group ; Blood Platelets* ; Daegu ; DNA ; Ethnic Groups ; Female ; Gene Frequency ; Genotype* ; Glycoproteins* ; Granulocytes* ; Humans ; Infant, Newborn ; Mass Screening ; Neutropenia ; Polymorphism, Restriction Fragment Length ; Pregnant Women ; Serotyping ; Thrombocytopenia ; Thrombocytopenia, Neonatal Alloimmune

Diffuse telangiectatic type of pulmonary arteriovenous malformation (AVM) is an uncommon disease entity in which numerous small arteriovenous connections occur throughout the lungs. It has rarely been confirmed by pulmonary angiography. We report a case of diffuse telangiectatic pulmonary AVM occurring in a patient with dyspnea and confirmed by CT using the slab maximum intensity projection (MIP) technique and conventional direct pulmonary angiography.
Angiography ; Arteriovenous Malformations* ; Dyspnea ; Humans ; Lung ; Tomography, X-Ray Computed*