1.Studies on the production and application of monoclonal antibodies against human gastrointestinal tumor cell lines(I).
Korean Journal of Immunology 1991;13(2):201-214
No abstract available.
Antibodies, Monoclonal*
;
Humans*
2.A Study of Surgical Outcome for Multiple Intracranial Aneurysms.
Kyu Hong KIM ; Jung Hoon CHOI ; Sang Do BAE
Journal of Korean Neurosurgical Society 2000;29(10):1322-1327
No abstract available.
Intracranial Aneurysm*
3.Conversion to Total Hip Arhoroplasty after Girdlestone Operation
Sung Kwan HWANG ; Yeu Seong YOON ; Do Kyu KIM
The Journal of the Korean Orthopaedic Association 1996;31(3):512-518
From Mar. 1984 to Mar. 1994, we carried out 18 revision operations in patients who received Girdlestone operation due to the infection of hip was 7 cases, tuberculosis of hip was 3 cases, deep infections after implant insertion of hip were 5 cases, and pyogenic sequela was 1 case. The mean conversion period was 27 months. The leg length discrepancy, range of motion of hip, and Trendelenberg gait were examined before and after conversion to a total hip arthroplasty. The last functional state was evaluated and radiological examination was performed. In summary and Conclusion; 1. The time of performing revision hip arthroplasty was assessed by clinical, radiologic and laboratory finding, and the average time of conversion to total hip arthroplasty was 7.6 months after Girdlestone operation. 2. There was no case of recurrence of infection after revision operations. 3. At last follow-up after revision hip arthroplasty, the mean Harris Hip Score was 87.2(69.6–92.2) point. 4. Six patients had no pain, 8 patients had mild pain, and 2 patients had moderate pain. Nine patients were able to walk without ambulatory aids and 7 patients needed crutch or cane for walking. 5. At the time of revision hip arthroplasty, the average shortening of the resected limb was 4.2cm(1.6–7.3cm), and after revision operation, the average shortening was reduced to 1.2cm(0.8–2.2cm) 6. The technical difficulties, such as increased bleeding, bone deficiency, scar tissue formation, and limb shortening were encountered in all cases. 7. The peroneal nerve injury was developed in one patient who had conversion hip arthroplasty at 13 months after Girdlestone operation.
Arthroplasty
;
Arthroplasty, Replacement, Hip
;
Canes
;
Cicatrix
;
Extremities
;
Follow-Up Studies
;
Gait
;
Hemorrhage
;
Hip
;
Humans
;
Leg
;
Peroneal Nerve
;
Range of Motion, Articular
;
Recurrence
;
Tuberculosis
;
Walking
4.Epidural Steroid and Morphine Injection for the Treatment of Low Back Pain
Sung Keun SOHN ; Jae Do KIM ; Kyu Yong LEE
The Journal of the Korean Orthopaedic Association 1989;24(4):1195-1200
The epidural injection of corticosteroid reduces the inflammatory process of the neural structure and its neighbor structures. Morphine, also injected epidurally, has been reported to alleviate severe pain with the short-acting property. In attempt to prolong the effectiveness of pain relief, we have studied the effect of the epidural injection of the morphine and steroid frorg May 1987 to Oct. 1987, and compared with the effect of the epidural injection of the steroid and local anesthetics from Jan. 1986 to Oct. 1987. In this study, we obtained following results; 1. The major causative diseases were herniated necleus pulposus in 34 cases(48.5%), spinal stenosis in 16 cases(22.9%) and spondylolisthesis in 9 cases(12.9%). 2. In morphine-injected group, 100% of acute group and 92.3% of chronic group was improved. In non-morphine injected group, there was no significant difference between the acute and chroinc groups. 3. The effect of epidural morphine and steroid was as follows; Complete relief 14 cases (63.6%), marked improvement 5 cases(22.7%), moderate improvement 2 cases(9.2%) and no relief 1 case(4.6%). The overall improvement was resulted in 21 cases(95.4%). 4. The effect of epidural steroid and local anesthetics was as follows; Complete relief 10 cases(20.8%), marked improvement 14 cases(29.2%), moderate improvement 12 cases(25%~ and no relief 12 cases(25%). The overall improvement was resulted in 36 cases(75%). 5. The average duration of pain relief was 2.5 months in morphine injected group and 1.3 months in non-morphine injected group. 6. The side effects associated with opiate, such as generalized pruritus, nausea, vomiting and urinary retention were reported in 16 cases(72.7%), but responded readily to Naloxone injection and subsided within 24 hours. It is considered that epidural injection of morphine and steroid prolong the effect and duration of pain relief for low back pain and sciatica when compared with the epidural injection of steroid and local anesthetics.
Anesthetics, Local
;
Injections, Epidural
;
Low Back Pain
;
Morphine
;
Naloxone
;
Nausea
;
Pruritus
;
Sciatica
;
Spinal Stenosis
;
Spondylolisthesis
;
Urinary Retention
;
Vomiting
5.Molecular Cloning of hSC2 Encoding 5α-reductase-like Protein.
Ho Chul SEO ; Do Won KIM ; Moon Kyu KIM ; Jung Chul KIM ; Sang Lip CHUNG
Annals of Dermatology 2000;12(4):252-258
BACKGROUND: The human homologue of the SC2 gene from a human dermal papilla cell cDNA library has been isolated and designated hSC2. HSC2 protein also shares similarity with 5 -reductase, a protein important in testosterone metabolism. OBJECTIVE: Prior to knowing the functions of hSC2 in dermal papilla, we cloned it and analyzed its relative expression levels in adult tissues and cancer cell lines. METHODS: hSC2 was isolated from low abundant clones in dermal papilla cDNA library using cDNA array hibridization method. Full-length clone was sequenced and we studied its expression in different tissues by Northern blot hybridization. RESULTS: Sequence data reveals a single open reading frame, encoding a putative hydrophobic protein with a calculated molecular weight of 36 kDa. Its deduced amino acid sequences are almost 97.4% identical to t4ose of rat protein. Northern blot hybridization shows that hSC2 cDNA recognizes a 1.35 kb transcript that was expressed in various epithelial and mesenchymal tissues including testis and liver. CONCLUSION: We have cloned and analysed tissue distributions of hSC2. It was interesting that it had homology with 5α-reductase isozymes. Further studies will be needed to understand the involvement of hSC2 in androgen hormone signaling.
Adult
;
Amino Acid Sequence
;
Animals
;
Blotting, Northern
;
Cell Line
;
Clone Cells
;
Cloning, Molecular*
;
DNA, Complementary
;
Gene Library
;
Humans
;
Isoenzymes
;
Liver
;
Metabolism
;
Molecular Weight
;
Oligonucleotide Array Sequence Analysis
;
Open Reading Frames
;
Rats
;
Testis
;
Testosterone
;
Tissue Distribution
6.A critical apprasial of fetal acoustic stimulation as an intrapartal test for fetal weel-being.
Dong Kyu KIM ; Yong Won PARK ; Do Hyung KIM ; Dong Hee CHOI ; Kyung SEO ; Tchan Kyu PARK
Korean Journal of Obstetrics and Gynecology 1991;34(4):461-470
No abstract available.
Acoustic Stimulation*
;
Acoustics*
7.A case of lymphomatoid granulomatosis.
Kyu Hyeong LEE ; Young Doo KIM ; Do Won KIM ; Jae Bok JUN
Korean Journal of Dermatology 1991;29(5):697-702
No abstract available.
Lymphomatoid Granulomatosis*
8.A study of the effect of estrogen on calcium metabolism during ovulation induction in patients with hypogonadism.
Do Hyung KIM ; Dong Kyu KIM ; Byung Seok LEE ; Ki Hyun PARK
Korean Journal of Obstetrics and Gynecology 1991;34(10):1410-1416
No abstract available.
Calcium*
;
Estrogens*
;
Female
;
Humans
;
Hypogonadism*
;
Metabolism*
;
Ovulation Induction*
;
Ovulation*
9.A case report of acquired nonmalignant treacheoesophageal fistula.
Jeong Seob YOON ; Kyu Do CHO ; Chi Kyung KIM ; Se Wha KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(8):800-805
No abstract available.
Fistula*
10.Clinical aspect of primary carcinoma of the fallopian tube report on 7 cases.
Do Hyung KIM ; Tchan Kyu PARK ; Se Kwan LAN ; Jae Wook KIM ; Dong Hee CHOI
Korean Journal of Obstetrics and Gynecology 1991;34(6):821-827
No abstract available.
Fallopian Tubes*
;
Female