No abstract available.
Carcinoma, Transitional Cell* ; Cystectomy* ; Urinary Bladder*

No abstract available.
Humans ; Osteochondrodysplasias*

No abstract available.
Leiomyosarcoma* ; Myosarcoma* ; Rhabdomyosarcoma*

No abstract available.
Humans ; Siblings*

No abstract available.
Paragonimiasis*

Gonadotropin-releasing hormone (GnRH) agonist has been used in the treatment of a wide variety of sex-hormone-related diseases, as the administration of GnRH agonist can alter the secretion of gonadotropin and sex hormones. Recently, we found that the long-acting GnRH agonist aggravated hyperthyroidism and induced painless thyroiditis. This is the first report to demonstrate the association of thyroid dysfunction with GnRH agonist injection in Korea. Here, we report three cases and emphasize the clinical importance of this aggravating factor in autoimmune thyroid disease.
Gonadal Steroid Hormones ; Gonadotropin-Releasing Hormone ; Gonadotropins ; Graves Disease ; Hyperthyroidism ; Korea ; Thyroid Diseases ; Thyroid Gland ; Thyroiditis

No abstract available.
Female ; Germ Cells* ; Neoplasms, Germ Cell and Embryonal* ; Ovary*

PURPOSE: To report a case of retinal detachment surgery in a patient with oculocutaneous albinism. CASE SUMMARY: A 44-year-old man visited our clinic complaining of decreased visual acuity in his left eye. His best corrected visual acuity was hand movement in his left eye, and rhegmatogenous retinal detachment involving the macula at the superior temporal site was found. We performed pars plana vitrectomy and attempted to reattach the retina using endolaser photocoagulation; however, the laser burn was not made, and we failed to reattach the retina. At that point, we carried out cryopexy around the retinal tear, and injected silicone oil into the vitreous cavity. Ten months after surgery, his best corrected visual acuity was 0.06, and there was no recurrent retinal detachment or proliferative vitreoretinopathy. CONCLUSIONS: In patients with albinism with melanin deficiency, cryopexy is more useful than laser photocoagulation for retinal detachment surgery.
Adult ; Albinism ; Albinism, Oculocutaneous ; Burns ; Eye ; Hand ; Humans ; Light Coagulation ; Melanins ; Retina ; Retinal Detachment ; Retinal Perforations ; Retinaldehyde ; Silicone Oils ; Visual Acuity ; Vitrectomy ; Vitreoretinopathy, Proliferative

PURPOSE: To report a case of occlusive retinal vasculitis in Churg-Strauss syndrome. CASE SUMMARY: A-48-year-old man visited our clinic complaining of suddenly decreased visual acuity in the left eye. Two months previously he had an operation for sinusitis, and he had been taking medications for asthma. In the initial examination, his best corrected visual acuity was 0.02 in the left eye. Fundus examination showed whitish, multiple, diffuse ischemic lesions around the posterior pole and slightly engorged retinal veins in the left eye. Fluorescein angiography showed delayed choroidal filling and delayed arteriovenous transit time in the left eye, but no apparently visible obstruction site. The eosinophil count was elevated to 65% in the white blood cell differentiated count, and perinuclear antineutrophil cytoplasmic antibodies (ANCA) with antimyeloperoxidase specificity (MPO-ANCA) was increased, but a chest X-ray was normal. Eosinophil infiltrations in the mucosa of the paranasal sinus were found, and peripheral neuropathy was found in a nerve conduction study. Hence, we diagnosed the patient with Churg-Strauss syndrome accompanied by occlusive retinal vasculitis, and started steroid therapy. Thirty days later after steroid therapy, the best corrected visual acuity of the left eye was 0.4. CONCLUSIONS: In patients with occlusive retinal vasculitis, we need to consider systemic diseases, such as Churg-Strauss syndrome.
Antibodies, Antineutrophil Cytoplasmic ; Asthma ; Choroid ; Churg-Strauss Syndrome ; Eosinophils ; Eye ; Fluorescein Angiography ; Humans ; Leukocytes ; Mucous Membrane ; Neural Conduction ; Peripheral Nervous System Diseases ; Retinal Vasculitis ; Retinal Vein ; Retinaldehyde ; Sensitivity and Specificity ; Sinusitis ; Thorax ; Visual Acuity

BACKGROUND: In chronic airway disease, mucus secretion in increased, but extraction of mucin, which is the main component of mucus secretion, is a very complicated and limited in clinical use. Recently, monoclonal antibody for mucin was developed for possible clinical use. In this study, cellular analysis and quantification of respiratory mucin in sputum of patients with chronic airway diseases were performed. METHOD: Sputum was collected from patients with asthma(n=33), bronchiectasis(n=8) or chronic bronchitis(n=13) by spontaneous expectoration or by hypertonic saline induction, Collected sputums was treated by 0.1% dithiotreitol to dissociate the disulfide bond of the mucus and filtered through a nylon gauze. Total cell count, viability and differential count were measured. For detection of mucin, collected samples were treated with sodium dodoecyl sulfate polyacrylamide gel electrophoresis and then with monoclonal antibody(HMO2), as the primary antibody, and PAS stain. The amount of mucin was measured with ELISA by HMO2. Correlation with clinical information, cellular analysis, and amount of measured mucin were analyzed. RESULTS: Total cell counts of sputum were significantly increased in patients with bronchiectasis but viability remained the same. Eosinophils were significantly increased in patients with asthma, neutrophils in bronchiectasis chronic bronchitis, respectively (p<0.05). The results of Western blotting and PAS staining confirmed the presence of glycoproteins and matched? with mucin. The amounts of mucin measured by ELISA were not significantly different among the disease groups. Significant correlation was identified between the amount of mucin and viability(r=-0.482, p<0.05). CONCLUSION: Inflammatory cells in the sputum of those with chronic airway disease were different for each disease type. Measurement of mucin by ELISA via monoclonal antibodies may be a simple method for the evaluation of chronic airway disease.
Antibodies, Monoclonal ; Asthma ; Blotting, Western ; Bronchiectasis ; Bronchitis, Chronic ; Cell Count ; Electrophoresis, Polyacrylamide Gel ; Enzyme-Linked Immunosorbent Assay ; Eosinophils ; Glycoproteins ; Humans ; Mucins* ; Mucus ; Neutrophils ; Nylons ; Sodium ; Sputum*