1.Effect of oxygenation of cardioplegic solution on postischemic recovery of cardiac function after ischemic arrest in isolated rat heart(II).
Jong Bum CHOI ; Tae Geun RIM ; Jae Do YOON ; Soon Ho CHOI ; Bong Kyu CHOI
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(12):1391-1398
No abstract available.
Animals
;
Cardioplegic Solutions*
;
Oxygen*
;
Rats*
2.Comparison of ramosetron and ondansetron for preventing nausea and vomiting after middle ear surgery under general anesthesia with sevoflurane and remifentanil.
Do Geun YOON ; Sang Ho JUNG ; Myung Hwa HA ; Nam Won SONG
Korean Journal of Anesthesiology 2009;56(4):408-412
BACKGROUND: In this randomized, double-blinded study, we evaluated the efficacy of ramosetron and ondansetron for preventing postoperative nausea and vomiting (PONV) after middle ear surgery. METHODS: Seventy patients of either sex, ASA 1-2, scheduled middle ear surgery (mastoidectomy and tympanoplasty) under general anesthesia with sevoflurane and remifentanil were included. Patients were randomly divided into two groups and received IV ramosetron 0.3 mg (group R) or ondansetron 4 mg (group O) before the end of operation (n = 35 each). The incidence and severity of PONV, pain score (VAS), rescue antiemetic, rescue analgesic and side effects were assessed following 6 hr, 24 hr and 48 hr after surgery. RESULTS: The incidence of PONV showed no significant difference between groups at each time points after surgery. There were no difference in the severity of nausea, pain score, rescue antiemetic, analgesic drug usage and side effects between groups. CONCLUSIONS: Prophylactic therapy with ramosetron is as effective and safe as conventional prophylactic therapy with ondansetron for preventing PONV in patients undergoing general anesthesia for middle ear surgery.
Anesthesia, General
;
Benzimidazoles
;
Ear, Middle
;
Humans
;
Incidence
;
Methyl Ethers
;
Nausea
;
Ondansetron
;
Piperidines
;
Postoperative Nausea and Vomiting
;
Vomiting
3.Verrucous Hemangioma and Angiokeratoma: Their Similarilities and Differences according to the Clinicopathological Features.
Hong Dae JUNG ; Kyung Duck PARK ; Seong Geun CHI ; Seok Jong LEE ; Yoon Seok CHOE ; Byung Soo KIM ; Do Won KIM ; Ho Yun CHUNG ; Ghil Suk YOON
Korean Journal of Dermatology 2009;47(4):419-424
BACKGROUND: Verrucous hemangioma (VH) and angiokeratoma (AK) are vascular birthmarks of an unclear nosology and these birthmarks commonly show a superficial hyperkeratotic vascular component. There are both similarilities and differences between VH and AK with some confusion concerning their overlapping features. OBJECTIVE: This study was undertaken to review the clinicopathological features of VHs and AKs and to determine the similarilities and differences between them. METHODS:We retrospectively reviewed 11 VHs and 7 AKs at the Vascular Anomaly Clinic of our hospital over the past 10 years. They were evaluated from the clinicopathologic point of view for factors such as the age of onset, location, size, symptoms, the histopathological epithelial change and involvement of deeper tissue. RESULTS: These birthmarks share common clinical features with the exception of gender and lesion size. Histopathologically, hyperkeratosis, acanthosis and capillary dilatation in the upper dermis were commonly seen. Yet lobular proliferation and dilatation of blood vessels in the deep dermis, or more importantly, the subcutis were detected in VH only. Furthermore there was a case of VH that showed diffusely scattered increased blood vessels in the subcutis, suggesting an evolving stage of VH and there was another case of VH that was erroneously diagnosed as AK via the initial biopsy, and the final diagnosis was changed according to the excised lesion. CONCLUSION:The two diseases share most of their clinicopathological features, but small parts of features like gender, the clinical size and the histological deep dermis/subcutis involvement were differences. Making the correct differential diagnosis between VH and AK through a deep biopsy with appropriate timing and long-term follow-up and/or radiological examination is helpful to avoid erroneous management.
Age of Onset
;
Angiokeratoma
;
Biopsy
;
Blood Vessels
;
Capillaries
;
Dermis
;
Diagnosis, Differential
;
Dilatation
;
Follow-Up Studies
;
Hemangioma
;
Retrospective Studies
4.Pararenal Leiomyosarcoma of the Inferior Vena Cava.
Tae Won KWON ; Kyu Bo SUNG ; Yong Pil CHO ; Do Kyun KIM ; Sun Mo YANG ; Jae Yoon RO ; Geun Eun KIM
Journal of Korean Medical Science 2003;18(3):355-359
A complete surgical resection is the only proven therapeutic modality that prolongs the survival in patients with leiomyosarcoma of the inferior vena cava (IVC). Reconstruction of the IVC is not always necessary but is often required to facilitate venous drainage of the kidney for the tumors at the pararenal area of the IVC. Controversy exists in postoperative adjuvant therapy. Recently, we experienced four cases of pararenal leiomyosarcoma of the IVC, of which treatment consisted of a complete resection of the tumor, ringed polytetrafluoroethylene (PTFE) graft interposition, and bilateral renal vein reconstructions in all patients. Postoperative radiation therapy was instituted in 3 of 4 patients. One patient who did not receive the postoperative radiation therapy was treated with adjuvant chemotherapy. The kidneys were preserved in all patients and no deep vein thrombosis (DVT) or venous insufficiency of the lower extremity veins developed. Distant metastasis to the lung was noted in one patient at 18 months after surgery, who was not received the postoperative radiation therapy but chemotherapy. In conclusion, a complete resection of the tumor, IVC reconstruction, and bilateral renal vein reconstruction followed by adjuvant radiation therapy is recommended for the treatment of pararenal leiomyosarcoma of the IVC.
Adult
;
Combined Modality Therapy
;
Female
;
Human
;
Leiomyosarcoma/radiography/*radiotherapy/*surgery
;
Middle Aged
;
Neoplasm Recurrence, Local/radiography/radiotherapy/surgery
;
Retroperitoneal Neoplasms/radiography/radiotherapy/surgery
;
Retrospective Studies
;
Treatment Outcome
;
Vascular Neoplasms/radiography/*radiotherapy/*surgery
;
*Vena Cava, Inferior
5.Clinicopathological Observation of Hemangioma of Infancy: The Diagnostic Usefulness of GLUT-1 Immunohistochemical Stain.
Seong Geun CHI ; Hong Dae JUNG ; Seok Jong LEE ; Byung Soo KIM ; Weon Ju LEE ; Do Won KIM ; Ho Yun CHUNG ; Ghil Suk YOON
Korean Journal of Dermatology 2009;47(4):386-394
BACKGROUND: Hemangioma of infancy (HOI) is one of the most common tumors in childhood. Their clinical features can on occasion look like those of other vascular tumors and malformations, so the correct differentiation of HOI may not always be easy. OBJECTIVE: The purpose of this study was to review the clinicopathological features of HOIs and to particularlyexamine the usefulness of glucose transporter protein isoform-1 (GLUT-1) immunohistochemical stain (IHS) as a specific marker of HOI. METHODS: This study was conducted at the Vascular Anomaly Clinic of Kyungpook National University Hospital during 11 years (1998~2008). Sixty-two cases were selected in addition to selecting other tumors and malformation as a control group. We then reviewed their clinical features and the results of H&E and GLUT-1 IHS for making the differential diagnosis. RESULTS: The male to female ratio was 1 : 2.88. The head and neck were the most commonly involved sites. The complications included ulceration and/or bleeding (12.9%), scarring (9.7%), infection (4.8%), ocular complications (4.8%) like visual axis occlusion, and pain (1.6%). Three phases of proliferating, involuting and involuted of a HOI comprised 11.3%, 37.1% and 51.6% of the lesions, respectively, from the clinical view point and 11.3%, 48.4% and 40.3% of the lesions, respectively, from the pathological point of view. GLUT-1 was positively expressed on almost all of the HOIs (47/57, 82.5%), except for 10 HOIs of the involuted phase and the other controls. CONCLUSION: The clinicopathological findings of this study were similar with those of the previous reports. The expression of GLUT-1 by a HOI can be helpful to make the correct diagnosis from other vascular tumors and malformations.
Axis, Cervical Vertebra
;
Cicatrix
;
Female
;
Glucose Transport Proteins, Facilitative
;
Head
;
Hemangioma
;
Hemorrhage
;
Humans
;
Iodine Compounds
;
Male
;
Neck
;
Ulcer
6.Four Cases of Capillary Aneurysm: Clinical Differential Diagnosis with Malignant Melanoma.
Seong Geun CHI ; Hong Dae JUNG ; Seok Jong LEE ; Byung Soo KIM ; Weon Ju LEE ; Do Won KIM ; Ghil Suk YOON
Korean Journal of Dermatology 2007;45(12):1265-1269
Capillary aneurysm is classically described as a suddenly growing dark papule, and is also known as thrombosed capillary or vein. It is clinically significant that the clinical features of capillary aneurysm are closely similar to those of malignant melanoma or dysplastic nevus. The histopathological finding of capillary aneurysm reveals dilated thin-walled venule(s) just beneath the hyperplastic epidermis, lined by a single layer of endothelium and a thrombus in the lumen. This abstract focuses on four patients who presented with a dark black-colored dome-shaped nodule and clinical impression included malignant melanoma, dysplastic nevus, angiokeratoma and lymphangioma circumscriptum. We herein report four cases histologically diagnosed as capillary aneurysm, which should be considered for differential diagnosis.
Aneurysm*
;
Angiokeratoma
;
Capillaries*
;
Diagnosis, Differential*
;
Dysplastic Nevus Syndrome
;
Endothelium
;
Epidermis
;
Humans
;
Lymphangioma
;
Melanoma*
;
Thrombosis
;
Veins
7.Clinicopathological Characteristics of Gastric Hepatoid Adenocarcinoma.
Jung Bin YOON ; Gwang Ha KIM ; Do Youn PARK ; Young Geum KIM ; Sung Ik PYEON ; Bong Eun LEE ; Geun Am SONG
The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2017;17(2):88-93
BACKGROUND/AIMS: Gastric hepatoid adenocarcinoma (GHA), a rare type of primary gastric cancer, is characterized by a histology resembling hepatocellular carcinoma. Previous case studies reported that patients with GHA have a poor prognosis due to early lymph node or liver metastasis, but information concerning GHA is still limited. Therefore, we aimed to evaluate the clinicopathological features of GHA. MATERIALS AND METHODS: We reviewed the medical records of 9 patients who were diagnosed as having GHA between January 2011 and December 2016. The clinicopathological characteristics of these patients were retrospectively analyzed. RESULTS: The median age of the patients at diagnosis was 68.9 years. Seven of the 9 patients were male. Serum AFP levels were elevated in 3 of 4 patients. All the tumors were >4 cm (range, 4~12 cm), and 7 tumors were located at the lower third of the stomach. Five tumors were classified as Borrmann's type 3, with a purple, berry-like surface. Of the 6 patients without distant metastasis, 5 received curative-intent surgery and 3 received adjuvant chemotherapy. Three patients with distant metastasis received either palliative operation and/or chemotherapy. Their median survival time was 11.8 months (range, 1~36 months). Two patients with elevated serum CEA levels had poor outcomes. CONCLUSIONS: GHA is a rare subtype of gastric cancer that is prone to liver metastasis. All GHAs are advanced gastric cancer with a purple, berry-like surface at diagnosis. Although the prognosis of advanced-stage GHA is poor, active multimodality treatment might provide some benefit.
Adenocarcinoma*
;
Carcinoma, Hepatocellular
;
Chemotherapy, Adjuvant
;
Diagnosis
;
Drug Therapy
;
Endoscopy
;
Humans
;
Liver
;
Lymph Nodes
;
Male
;
Medical Records
;
Neoplasm Metastasis
;
Prognosis
;
Retrospective Studies
;
Stomach
;
Stomach Neoplasms
8.A Case of an Esophageal Schwannoma with Intense FDG Uptake as Detected on PET-CT.
Seong Hoon YOON ; Gwang Ha KIM ; Do Youn PARK ; Ho Seok LEE ; Jung Ho BAE ; Jin Hyun PARK ; Su Bum PARK ; Geun Am SONG
Korean Journal of Gastrointestinal Endoscopy 2008;37(5):339-343
An esophageal schwannoma originating in a schwann cell of a neuron presents as a type of submucosal tumor. An esophageal schwannoma is extremely rare, with only 30 reported cases. It is usually a benign tumor. However, three cases with malignant findings and one case with local recurrence have been reported. Reviews of previous reports indicate that benign schwannomas are usually located in the upper esophagus and occur in middle aged-women. An esophageal schwannoma is usually asymptomatic but sometimes causes dysphagia as an initial symptom and dyspnea by trachea compression. The differentiation of a schwannoma from the other submucosal tumors is very difficult on a preoperative examination with the use of esophagoscopy, endoscopic ultrasound and computed tomography. A definite diagnosis of the tumor requires a histological examination and immunohistochemical staining. Positive immunostaining for s-100 protein supports the schwann cell origin of the tumor. We report a case of an esophageal schwannoma with intense FDG uptake as detected on PET-CT.
Deglutition Disorders
;
Dyspnea
;
Esophagoscopy
;
Esophagus
;
Neurilemmoma
;
Neurons
;
Recurrence
;
S100 Proteins
;
Trachea
9.Three Cases of Pancreatic Pseudocyst Treated with Transpapillary Endoscopic Management of Pancreatic Duct Disruption after Percutaneous Drainage as a First-line Treatment.
Jee Heon KANG ; Do Hyun PARK ; Sang Heum PARK ; Hyung Geun YOON ; Suck Ho LEE ; Il Kwun CHUNG ; Hong Soo KIM ; Sun Joo KIM
The Korean Journal of Gastroenterology 2007;49(2):100-105
Previously reported series suggested that the morbidity rate of internal surgical drainage procedure alone was about 15% and the mortality rate was less than 5% in patients with pancreatic pseudocysts. Recently, ultrasonography or CT-guided percutaneous drainage and endoscopic drainage techniques have created a new dimension of invasive, non-surgical treatment options for these patients. In the absence of prospective, randomized, controlled studies comparing outcomes of different pseudocysts drainage techniques, the decision as to which method should be employed often lies with local expertise and enthusiasm. In our experience, radiologic percutaneous drainage with subsequent transpapillary endosopic drainage had a high success rate and was relatively less difficult which resulted in rapid clinical improvement. We report three cases of pancreatic pseudocysts treated with percutaneous drainage as a first-line treatment followed by endoscopic treatment.
Aged
;
*Cholangiopancreatography, Endoscopic Retrograde
;
*Drainage/instrumentation
;
Female
;
Hemostasis, Surgical
;
Humans
;
Male
;
Middle Aged
;
Pancreatic Ducts/radiography
;
Pancreatic Pseudocyst/*radiography/*therapy
;
Tomography, X-Ray Computed
10.Comparison between Mammography and Ultrasonography for Palpable Breast Mass: Focusing Fibroadenoma and Breast Cancer.
Do Kyun KIM ; Mi Kyung KOH ; Chul Soon CHOI ; Soo Young CHUNG ; Jeong Geun YI ; Dae Young YOON ; Ho Chul KIM ; Sang Hoon BAE
Journal of the Korean Radiological Society 1997;37(3):561-565
PURPOSE: The purpose of our study was to compare the diagnostic accuracy of mammography and breast ultrasonography between fibroadenoma and palpable breast cancer and to evaluate the feasibility of ultrasonography as a primary diagnostic modality to differentiate between these two tumor types. MATERIALS AND METHODS: In 36 cases of fibroadenoma and 35 of breast cancer, all palpable and pathologically-proven, the diagnostic accuracy of mammography and ultrasonography was retrospectively analysed. RESULTS: In fibroadenoma cases, the diagnostic accuracy of mammography and ultrasonography was 53% and 80%, respectively, and the difference was statistically significant (p=0.0162). In cases of breast cancer, the corresponding figures were 74% and 82%, respectively ; the difference was not statistically significant (p=0.55). Overall, the diagnostic accuracy of mammography and ultrasonography was 63% and 82%, respectively, and this difference was statistically significant (p=0.0164). The total diagnostic accuracy of both studies was 90%, and this was significantly different (p=0.044) from that of ultrasonography (82%). CONCLUSION: In patients who have clinically palpable breast masses, ultrasonography can be recommended as the primary diagnostic modality, though for other breast lesions, mammography is the recommended primary modality.
Breast Neoplasms*
;
Breast*
;
Fibroadenoma*
;
Humans
;
Mammography*
;
Retrospective Studies
;
Ultrasonography*
;
Ultrasonography, Mammary