No abstract available.
Disulfiram*

No abstract available.
Disulfiram*

A study on 44 schizophrenic (male: 5; female: 39), ages of 16-45 who had signs of eating refusal within 2 days in the Central Metal Hospital has shown that most of them were female patients (88,6%); eating refusal were due to the delirium (45,4%), hallucination (40,9%) and sense loss (61,4%); the average weightloss occurred strongly in the schizophrenics type hypertonicity. The patients should be timely treated.
Disulfiram ; Schizophrenia

Through clinical investigation on 44 cases of eating refusal of schizophrenia patients, we have realized that the number of depression, schizophrenia who have eating refusal symptom accounts for 45.5%; So depression is the most important causes of the of the syndrome of schizophrenia, otherwise that is the cause of suicide and impulse behavior of patient. Thus, if delusion or hallucination is not the causes of eating refusal syndrome of patients, we have to define the depression elements for a best method of treatment.
Disulfiram ; Schizophrenia

No abstract available.
Disulfiram* ; Psychotic Disorders*

No abstract available.
Acetaldehyde* ; Disulfiram* ; Ethanol* ; Patch Tests*

BACKGROUND: When it comes to wasting blood components, it usually means wastage before transfusion due to several reasons such as improvement of the patient's condition, death of the patient, delay of blood returning, etc. Yet blood components can sometimes can be wasted after a transfusion is started and this is referred as residual blood wastage. In this study, we analyzed the rate and causes of discarded blood components that are not used and the residual blood wastage in order to help reduce the rate of blood component wastage. METHODS: From January 2009 to December 2010, the number of and the reasons for discarded blood components without use and residual blood wastage were analyzed by reviewing the laboratory information system and wastage statements at Soonchunhyang University Seoul Hospital. RESULTS: The number of blood components issued during the study period was 24,001 units. Among them, the number of units discarded without use was 162 units (0.7%) and the number of units of residual blood wastage was 115 units (0.5%). Among the reasons for the discarded blood component without use, improvement of the patient's conditions ranked as 1st with 80 units (49.5%) and death of the patient ranked as 2nd with 42 units (25.9%). The biggest reason for the residual blood wastage was transfusion-related side effects with as many as 52 units (45.2%). Other than side effects, the wastage of residue from pediatric transfusion were 48 units (41.7%), followed by delay of surgery with 5 units (4.3%) and patients' refusal with 4 units (3.5%). CONCLUSION: The wastage of residue from pediatric transfusion was the second most common cause of residual blood wastage in our hospital. According to this, we should evaluate the routine use of pediatric transfusion bags and their cost-effectiveness in our hospital.
Clinical Laboratory Information Systems ; Disulfiram ; Humans ; Korea

BACKGROUND: The blood component wastage leads to an unnecessary expensive cost of operation, and thus we have monitored the reasons for such wastage and have taken corrective actions to reduce the amount of discarded blood. METHODS: To evaluate the effectiveness of the corrective actions for blood wastage, rates and reasons for blood wastage were compared during the monitoring period of 78 months and the pre-monitoring period of 6 months. RESULTS: The wastage rates of total blood components, red blood cells (RBC), platelet concentrates (PC) and fresh frozen plasmas (FFP) for the pre-monitoring were 1.23%, 1.31%, 0.59% and 2.19%, and for the monitoring period 0.4%, 0.15%, 0.19% and 1.4%, respectively. These differences were statistically significant (P<0.001). The reasons for RBC wastage were inattention of the hospital staff 26.9%, moving of blood along with the patients 20.2%, death or discharge because of hopelessness 17.8%, refusal of the patients 13.9%, mishandling of blood by hospital staff 8.7%, the change in the patient's condition 7.7% and other 4.0%. The reasons for PC wastage were death or discharge because of hopelessness 56.0%, inattention of the hospital staff 19.4%, the change in the patient's condition 16.0%, mishandling of blood by hospital staff 4.9% and refusal of the patient 3.7%. CONCLUSION: Continuous corrective actions and monitoring of the blood wastage were effective in reducing the rates of wastage, particularly the RBC.
Blood Platelets ; Disulfiram ; Erythrocytes ; Humans ; Plasma

PURPOSE: Local excision, including transanal endoscopic microsurgery (TEM), has become an alternative to the classic radical operation for early rectal cancer. However, radical resection for rectal cancer is necessary for advanced tumor, poor differentiation, a narrow resection margin, and positive lymphovascular invasion. This study presents the factors related to recurrence in patients who required secondary radical surgery after TEM, but did not undergo the operation. METHODS: From November 1994 to December 2004, 167 patients underwent TEM for rectal cancer. Thirty-six of those patients were included in this study. Inclusion criteria were poor differentiation, a mucinous carcinoma, invasion to a proper muscle layer, lymphovascular invasion, and a positive resection margin. RESULTS: Twelve of the 36 patients underwent a secondary radical operation, but 24 of them did not due to poor general condition or refusal. One of 12 patients (8.3%) who underwent a secondary radical operation had a systemic recurrence. Five of 24 patients (20.8%) who did not receive surgery had recurrences; 3 of 5 were local recurrence, and the others were distant metastases. Among the 24 patients who did not undergo a secondary radical operation, there were no recurrences in 2 cases of poor differentiation or mucinous carcinoma and in 2 cases of positive resection margin. There were 2 cases of recurrences in the 7 patients (25.0%) who had lymphovascular invasion, 1 case in the 1 patient (100%) who had a T3 lesion, 3 cases in the 17 patients (12.5%) who had T2 lesions. CONCLUSIONS: In high-risk patients, TEM followed by radical surgery is most beneficial in preventing local recurrence. A radical operation is strongly recommended especially if pathologic results after TEM shows T3 lesions or lymphovascular invasion.
Adenocarcinoma, Mucinous ; Disulfiram ; Humans ; Microsurgery* ; Neoplasm Metastasis ; Rectal Neoplasms* ; Recurrence

PURPOSE: This study is to see how much proportion of the patients receiving radiation therapy drop out during radiation therapy and to analyze the reason for the incomplete treatment. MATERIALS AND METHODS: The base population of this study was 1,100 patients with registration numbers 901 through 2,000 at Department of Radiation Oncology, Samsung Medical Center, Seoul, Korea. Authors investigated the incidence of incomplete radiation therapy, which was defined as less than 95% of initially planned radiation dose, and the reasons for incomplete radiation therapy. RESULTS: One hundred and twenty eight patients (12%) did not complete the planned radiation therapy. The performance status of the incompletely treated patients was generally poorer than that of the base population, and the aim of radiation therapy was more commonly palliative. The most common reason for not completing the planned treatment was the patients' refusal of further radiation therapy because of the distrust of radiation therapy and/or the poor economic status. CONCLUSION: Careful case selection for radiation therapy with consideration of the socioeconomic status of the patients in addition to the clinical indication would be necessary for the reduction of incomplete treatment, especially in the palliative setting.
Disulfiram ; Humans ; Incidence ; Korea ; Radiation Oncology ; Seoul ; Social Class