No abstract available.
Disulfiram*

No abstract available.
Disulfiram*

A study on 44 schizophrenic (male: 5; female: 39), ages of 16-45 who had signs of eating refusal within 2 days in the Central Metal Hospital has shown that most of them were female patients (88,6%); eating refusal were due to the delirium (45,4%), hallucination (40,9%) and sense loss (61,4%); the average weightloss occurred strongly in the schizophrenics type hypertonicity. The patients should be timely treated.
Disulfiram ; Schizophrenia

Through clinical investigation on 44 cases of eating refusal of schizophrenia patients, we have realized that the number of depression, schizophrenia who have eating refusal symptom accounts for 45.5%; So depression is the most important causes of the of the syndrome of schizophrenia, otherwise that is the cause of suicide and impulse behavior of patient. Thus, if delusion or hallucination is not the causes of eating refusal syndrome of patients, we have to define the depression elements for a best method of treatment.
Disulfiram ; Schizophrenia

No abstract available.
Disulfiram* ; Psychotic Disorders*

No abstract available.
Acetaldehyde* ; Disulfiram* ; Ethanol* ; Patch Tests*

BACKGROUND: When it comes to wasting blood components, it usually means wastage before transfusion due to several reasons such as improvement of the patient's condition, death of the patient, delay of blood returning, etc. Yet blood components can sometimes can be wasted after a transfusion is started and this is referred as residual blood wastage. In this study, we analyzed the rate and causes of discarded blood components that are not used and the residual blood wastage in order to help reduce the rate of blood component wastage. METHODS: From January 2009 to December 2010, the number of and the reasons for discarded blood components without use and residual blood wastage were analyzed by reviewing the laboratory information system and wastage statements at Soonchunhyang University Seoul Hospital. RESULTS: The number of blood components issued during the study period was 24,001 units. Among them, the number of units discarded without use was 162 units (0.7%) and the number of units of residual blood wastage was 115 units (0.5%). Among the reasons for the discarded blood component without use, improvement of the patient's conditions ranked as 1st with 80 units (49.5%) and death of the patient ranked as 2nd with 42 units (25.9%). The biggest reason for the residual blood wastage was transfusion-related side effects with as many as 52 units (45.2%). Other than side effects, the wastage of residue from pediatric transfusion were 48 units (41.7%), followed by delay of surgery with 5 units (4.3%) and patients' refusal with 4 units (3.5%). CONCLUSION: The wastage of residue from pediatric transfusion was the second most common cause of residual blood wastage in our hospital. According to this, we should evaluate the routine use of pediatric transfusion bags and their cost-effectiveness in our hospital.
Clinical Laboratory Information Systems ; Disulfiram ; Humans ; Korea

BACKGROUND: The blood component wastage leads to an unnecessary expensive cost of operation, and thus we have monitored the reasons for such wastage and have taken corrective actions to reduce the amount of discarded blood. METHODS: To evaluate the effectiveness of the corrective actions for blood wastage, rates and reasons for blood wastage were compared during the monitoring period of 78 months and the pre-monitoring period of 6 months. RESULTS: The wastage rates of total blood components, red blood cells (RBC), platelet concentrates (PC) and fresh frozen plasmas (FFP) for the pre-monitoring were 1.23%, 1.31%, 0.59% and 2.19%, and for the monitoring period 0.4%, 0.15%, 0.19% and 1.4%, respectively. These differences were statistically significant (P<0.001). The reasons for RBC wastage were inattention of the hospital staff 26.9%, moving of blood along with the patients 20.2%, death or discharge because of hopelessness 17.8%, refusal of the patients 13.9%, mishandling of blood by hospital staff 8.7%, the change in the patient's condition 7.7% and other 4.0%. The reasons for PC wastage were death or discharge because of hopelessness 56.0%, inattention of the hospital staff 19.4%, the change in the patient's condition 16.0%, mishandling of blood by hospital staff 4.9% and refusal of the patient 3.7%. CONCLUSION: Continuous corrective actions and monitoring of the blood wastage were effective in reducing the rates of wastage, particularly the RBC.
Blood Platelets ; Disulfiram ; Erythrocytes ; Humans ; Plasma

Disulfiram is the commonly prescribed drug for the treatment of alcohol dependence. It's major metabolite (diethyldithiocarbamate) is an inhibitor of dopamine-betahydroxylase, an enzyme that catalyzes the metabolism of dopamine to norepinephrine resulting in psychosis. We recommend that disulfiram should be used at the lowest effective dose, possibly 250 mg daily and caution should be taken while prescribing disulfiram for patients with personal and familial antecedents of psychosis.
Alcoholism ; Disulfiram* ; Dopamine ; Humans ; Metabolism ; Norepinephrine ; Psychotic Disorders*

Seperation anxiety disorder(SAD) is characterized by excessive anxiety about being apart from the individuals to whom a child is most attached. We noticed a case of a 13 year old boy's SAD with symptoms of nausea/vomiting, stomachache, school refusal, and severe weight loss. His mother was overanxious and overdependent but her'dependency was frustrated due to family problem. We investigated this case from a point of developmental aspect and family dynamics and tried to attempt therapeutic approach.
Anxiety Disorders* ; Anxiety* ; Child* ; Disulfiram* ; Humans ; Mothers ; Weight Loss*