Osteonecrosis is a common disease, mainly affecting femoral head. Good animal models are helpful in research on the pathologic mechanism of osteonecrosis and the exploration of effective treatment. Although it is relatively easy to establish animal models of early osteonecrosis of femoral head using various approaches, it is difficult to develop an animal model that mimics the full range of osteonecrosis of femoral head. In this paper, we reviewed the current researches on experimental animal models of osteonecrosis, with an attempt to provide evidences for choosing the appropriate animal models and find the way of future development.
Animals ; Disease Models, Animal ; Osteonecrosis

Animals ; Disease Models, Animal ; Parkinson Disease ; Zebrafish

Animals ; Disease Models, Animal ; Hepatitis, Autoimmune

Animals ; Disease Models, Animal ; Integrative Medicine

Animals ; Disease Models, Animal ; Integrative Medicine

Animal models of coronary microcirculation dysfunction are useful in research on the pathology of coronary microcirculation dysfunction and its intervention mechanisms. Currently, such animal modes are prepared mainly by mechanical obstruction and chemical damage form coronary microembolization or microthrombosis. This paper summarizes the currently available preparation techniques and compared their advantages and disadvantages.
Animals ; Coronary Thrombosis ; Disease Models, Animal ; Microcirculation

OBJECTIVETo probe into the selection of parameters of electroacupuncture and analyze some problems.

METHODSAnalyze and study on the relevant literature about the application of electroacupuncture in the past 5 years and analyze the parameters of electroacupuncture in the literature in detail.

RESULTSMost of literature paid greater attention to the selection of parameters of electroacupuncture, but different electroacupuncture apparatuses were used with different electroacupuncture parameters.

CONCLUSIONThe selection of the electroacupuncture apparatus and electroacupuncture parameters does not have an unified standard, influencing comparability and reference of experimental and clinical results.

Deep venous thrombosis is a common and serious complication after orthopedics operation, with the characteristics of high incidence rate and death rate, its formation mechanism and the treatment is becoming more and more attention of scholars. Establishment of animal model of deep venous thrombosis can further explore the pathological process of thrombosis or dissolution, is an important means to research of thrombosis mechanism and evaluation of therapeutic method. This review discussed the basic principle of deep venous thrombosis, the selection of experimental animals and making method of animal models.
Animals ; Disease Models, Animal ; Venous Thrombosis ; etiology

Animals ; Disease Models, Animal ; Liver Failure

Animals ; Disease Models, Animal ; Heart Failure