1.Discussion on medical education administration system reform in local comprehensive university
Yongqin ZHOU ; Ding YUAN ; Yun ZHAO
Chinese Journal of Medical Education Research 2013;(6):541-543
This article elaborated on the necessity and importance of reform of medical education administration system in comprehensive university in promoting comprehensive development of medical education,from the point of merging of universities.It also emphasized the long-term nature and complexity of the reform process.In the meantime,it introduced the reform measures and effects of the reform in the author's university.
2.Effect of Chinese Herbal Fumigation Combined with Tuina on Vertigo and Concentrations of Endothelin and Calcitonin Gene-related Peptide in Patients with Vertebral Artery Cervical Spondylosis
Chengfei ZHAO ; Xiaoan LIU ; Yun DING
Journal of Acupuncture and Tuina Science 2014;(6):335-340
Objective:To observe the effect of Chinese herbal fumigation combined with three-step tuina manipulation on concentration of endothelin (ET) and calcitonin gene-related peptide (CGRP) and vertigo in patients with vertebral artery cervical spondylosis (VACS).
Methods:A total of 120 eligible cases were randomly allocated into an observation group and a control group, 60 in each group. Cases in the observation group were treated with Chinese herbal fumigation combined with three-step tuina manipulation, whereas cases in the control group were treated with oral Flunarizine Hydrochloride Capsules.
Results: After treatment, vertigo in both groups was alleviated; there were intra-group significant differences in ET decrease and CGRP increase (P<0.01, P<0.05);and there were also inter-group significant differences (both P<0.05).
Conclusion: Chinese herbal fumigation combined with three-step tuina manipulation can regulate the levels of ET and CGRP and improve vertigo in patients with VACS. Its therapeutic efficacy is superior to oral Flunarizine Hydrochloride Capsules.
4.Investigation of Removal of Proteins in Raw Milk, Infant Formula and Yogurt
Xiaojing DING ; Yuanyuan YANG ; Yun LI ; Shan ZHAO ; Zhi WANG
Chinese Journal of Analytical Chemistry 2010;38(1):77-81
On the basis of the development of a new CE method for the analysis of α-lactalbumin (α-Lac), β-lactoglobulin A(β-LgA) and β-lactoglobulin B(β-LgB), different concentrations of acetic acid (HAc) and trichloroacetic acid (TCA) for the removal of proteins in raw milk, infant formula A and B, and yogurt were investigated.It was shown that TCA is better than HAc for eliminating of proteins in the above four samples.The proteins in 2 g of raw milk could be eliminated by 3 mL of 100 g/L TCA.0.5 g of infant formula A and B needs 5 mL of 10 g/L and 20 g/L TCA to remove the proteins, respectively.For 2 g of yogurt, 3 mL of 20 g/L TCA is enough.The present research may provide valuable information for protein-containing sample (such as raw milk, infant formula and yogurt) pretreatment.
5.Correlation of self-efficacy and positive degree of cervical spondylosis patients
Hongyun ZHAO ; Qun LI ; Hong DING ; Lei CAO ; Yun GU
Modern Clinical Nursing 2016;15(11):23-26
Objective To investigate the relationship between self-efficacy and positive degree in patients with cervical spondylosis.Method A questionnaire survey was conducted among 98 patients with cervical spondylosis.Results The self-efficacy score was 6.30±1.56,the score on the positive degree was 53.76 ±12.53.The self-efficacy and positive degrees were positively correlated (r=0.531,P<0.001).Conclusions The patient's self-efficacy and positive degree are at medium level.Nursing staff should take corresponding measures to improve self-efficacy of cervical spondylosis patients,in order to improve its positive degree and achieve the purpose of effective self-management and health promotion.
6.Studies on the alkaloids from Salsola collina Pall.
Acta Pharmaceutica Sinica 2004;39(8):598-600
AIMTo study the chemical constituents of Salsola collina Pall..
METHODSCompounds were isolated by silica gel column chromatography. IR, MS, 1HNMR, 13CNMR, HMQC, HMBC, DEPT were used for the structural identification.
RESULTSTwo amide alkaloids were obtained. They were identified as N-transferuloyl-3-methyldopamine (I), (10bS)-1,2,3,5,6, 10b-hexahydropyrrolo [2,1-a]-8,9-dihydroxyisoquinoline-3-one (II).
CONCLUSIONCompound I was isolated from this genus for the first time. Compound II is a new compound named salsoline A.
Molecular Structure ; Plants, Medicinal ; chemistry ; Salsola ; chemistry ; Salsoline Alkaloids ; chemistry ; isolation & purification
7.Cerebral angiography and prognosis of acute cerebral ischemia infarction in elderly patients
Zhuoyou CHEN ; Wenwei YUN ; Jinwei ZHAO ; Hongbing XIANG ; Zhixiang ZHANG ; Guanzhong DONG ; Chuanzhong QIAN ; Xinsheng DING
Chinese Journal of Geriatrics 2011;30(3):199-202
Objective To investigate the distribution and severity of cerebral artery stenosis and the prognosis in elderly patients with acute cerebral infarction using digital subtraction angiography (DSA). Methods The 432 elderly patients with acute cerebral ischemia infarction underwent DSA,and they were divided into two groups: elderly group (n= 320) and non-elderly group (n= 112). The characteristics of distribution and severity of cerebral artery stenosis, the relationship between artery stenosis and relative risk factors, and the prognosis of acute cerebral infarction were analyzed.Results In elderly group, 270 cases (84.3%) had intra- and extra- cranial artery stenosis, of which 98 patients (30.6%) with pure extracranial arterial stenosis, 132 patients (41.3%) with combined extra- and intra-cranial artery stenosis. They were both significantly higher than the corresponding data in non-elderly group [23 cases (20.5%) and 28 cases (25%), P<0.05 and 0.01]. The prevalences of moderate and severe cerebral artery stenosises were higher in elderly group than in nonelderly group [224 locations (52.1%) vs. 51 locations (40.8%), P<0. 05]. The number of patients with previous history of cerebrovascular disease was much more and the prognosis was much worse in elderly group than in non-elderly group (both P<0.05), Conclusions The elderly patients with cerebral infarction have severer cerebral artery stenosis, increased proportion of multivessel disease and poor prognosis. So it is very important to take aggressive treatment as soon as possible, and to make secondary prevention and effective rehabilitation so as to improve their prognosis.
8.The prospective trends and bias of clinical scientific research regarding recent grants in a hospital
Yu QI ; Nan XIE ; Minghui ZHAO ; Yun LIU ; Yuping WEI ; Jie DING
Chinese Journal of Medical Science Research Management 2011;24(4):241-243
Based on the investigation of a hospital's grants during 2004-2005 and the authorized during 2002-2005 (385 in total), we tried to find the trends and bias of clinical sciences at present. We analysed on the types of grants (clinical or basic), research objects, experimental methods, discipline involved, modes of cooperation, and background of applicants. A close connection between research and clinical trial, interdisciplinary study, patient-centered practice and international competitions are becoming more and more important. To meet the needs of clinical research, policies and devotions such as technical platforms are needed.
9.Relationship between the homocysteine level and stroke
Jiong ZHOU ; Song-zhao ZHANG ; Yun ZHANG ; Zhong CHEN ; Meiping DING
Chinese Journal of Rehabilitation Theory and Practice 2004;10(3):183-184
ObjectiveTo study the relationship between the homocysteine (Hcy) level and stroke. Methods57 cases, including cerebral haemorrhage (CH, 21 cases) and cerebral infarction (CI, 36 cases) , and 28 healthy cases as control group were selected to measure their level of Hcy, VitB12 , folic acid and creatinine(Cr). At the same time, the clinical neurological disfunction scale(CNDS) of all patients was evaluated and the hematom volume (HV) of the CH group was assayed. ResultsThe Hcy level of both CI and CH group was significantly higher than that of the control group(P<0.05 or P<0.01). No significant difference was found between CI and CH group on Hcy level. The Hcy level showed a very strong or strong reverse association with folic acid level in the CI and CH group (r=-0.442,P=0.007 or r=-0.531,P=0.013), but no significant correlation with VitB12 level. No correlation was found between Hcy level and CNDS in both the CI and CH group, either no correlation between Hcy level and HV in the CH group. ConclusionThere is a close relationship between hyperhomocysteine and stroke. Hcy level is reversely associated with folic acid level but not correlated with VitB12 level.
10.Evaluation of sampling by tracheal aspiration and nasopharyngeal swabs in the identification of bacterial etiology of acute lower respiratory tract infection in children.
Rong CHEN ; Gen-Ming ZHAO ; Yu-Zun LIN ; Chuang-Li HAO ; Yun-Fang DING
Chinese Journal of Contemporary Pediatrics 2010;12(5):393-395
Acute Disease
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Bacteria
;
isolation & purification
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Child, Preschool
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Haemophilus influenzae
;
isolation & purification
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Humans
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Infant
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Infant, Newborn
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Nasopharynx
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microbiology
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Respiratory Tract Infections
;
diagnosis
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microbiology
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Streptococcus pneumoniae
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isolation & purification
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Trachea
;
microbiology