Periodontal ligament may have independent response to orthodontic stimulation and thus initiate alveolar bone osteogenesis and osteoclasts. Orthodontic-induced alveolar bone remodeling has no bone loss,while inflammation can lead to alveolar bone loss,suggesting that force signal and inflammatory factors may induce the differentiation of undifferentiated cells in the periodontal ligament via different pathways. The strength of the force and the nature of the force (basal tension and fluid shear force) may affect the differentiation of periodontal ligament cells,and may produce antagonistic or synergistic effect with the inflammatory factors through complex autocrine and paracrine regulation,resulting in local bone reconstruction,which is manifested as bone deposition and bone absorption. Studies have shown that Wnt signaling is an important regulatory pathway for osteoblast differentiation. Inflammatory factors can block the differentiation of stem cells into osteoblasts. The Wnt pathway is closely related to the effects of force and inflammatory factors on the differentiation of periodontal ligament cells.

Objective To investigate the effects of proprioceptive training and core stability training on the lower limbs motor function and balance in patients with hemiplegia after stoke. Methods 40 patients were randomly divided into treatment group (n=20) and control group (n=20). Both groups received routine rehabilitation and the treatment group received proprioceptive training and core stability training in addition. They were assessed with Fugl-Meyer Assessment (FMA) of lower limbs, Functional Ambulation Category (FAC), Berg Balance Scale (BBS), Timed Up-and-Go Test (TUGT) before and 6 weeks after treatment. Results The scores of FMA, FAC, BBS and TUGT improved in both groups after treatment (P<0.01), and improved more in the treatment group than in the control group (P<0.05). Conclusion Addition of proprioceptive training and core stability training may further improve the lower limbs motor function and balance of the hemiplegics after stroke.

Objective To observe the effect of comprehensive rehabilitation on breast cancer related lymphedema. Methods 70 patients with breast cancer related lymphedema were divided into experiment group (n=35) and control group (n=35). Both groups received intermittent pneumatic compression, while the experiment group received comprehensive rehabilitation including manual lymphatic drainage, muscle stretching, expanded the range of motion of shoulder, gradual resistance training, high frequency electrical therapy and health education. They were assessed with Disabilities of Arm, Shoulder and Hand Scale (DASH) and development of lymphedema before and 8 weeks after treatment. Results DASH scores and the development of lymphedema improved in both groups after treatment (P<0.05), and improved more in the experiment group than in the control group (P<0.05). Conclusion Comprehensive rehabilitation can further relieve breast cancer related lymphedema, and improve the upper extremity function.

Carcinoma, Hepatocellular ; diagnosis ; therapy ; Gastroenterology ; trends ; Hepatitis, Viral, Human ; diagnosis ; therapy ; Humans ; Liver Cirrhosis ; diagnosis ; therapy ; Liver Diseases ; diagnosis ; therapy ; Liver Failure, Acute ; etiology ; therapy ; Liver Neoplasms ; diagnosis ; therapy ; Retrospective Studies

Hepatolenticular Degeneration ; Humans ; Nervous System Diseases

Antiviral Agents ; therapeutic use ; Hepatitis B ; drug therapy ; Hepatitis C ; drug therapy ; Humans ; Interferons ; therapeutic use

Antiviral Agents ; therapeutic use ; DNA, Viral ; blood ; Hepatitis B ; immunology ; therapy ; Hepatitis B e Antigens ; blood ; Hepatitis B virus ; immunology ; Humans ; Immunotherapy

Interferons ; Liver Diseases

Humans ; Liver Cirrhosis ; therapy

Antiviral Agents ; therapeutic use ; Hepatitis B ; drug therapy ; Humans ; Prospective Studies