1.Effects of acupuncture and moxibustion of Yangchi point on carpal tunnel syndrome
International Journal of Traditional Chinese Medicine 2013;(2):117-119
Objective To explore the difference of treating carpal tunnel syndrome (CTS) with needling Yangchi point and moxibustion on Yangchi point.Methods 38 cases of CTS were randomly recruited into a treatment group (19 cases) and a control group (19 cases).The treatment group was treated with electric acupuncture on Yangchi point and the control group was treated with moxibustion on Yangchi point.VAS (visual analogue scale) and GSS (overall symptom score table) scores were measured before and after the treatment.Results After the treatment VAS,GSS scores were (3.95± 1.87),(13.42±7.81) in the treatment group and (4.26±2.38),(14.63±9.97) in the control group,both decreased than those in the same group before the treatment [treatment group were (6.89± 1.56),(25.58±8.09) ; the control group were (5.79± 1.69),(20.37±8.67)],and the difference between the two groups was significant (t=-3.06,-3.39,P<0.05).3 months follow-up after the treatment,the value of VAS and GSS scores in treatment group were (3.29±2.31)% and (8.06±7.77); in the control group were (3.28±2.95) and (10.44±9.82),both decreased than those in the same group before the treatment [treatment group were (6.76± 1.56),(24.76±8.17); the control group were (5.78± 1.73),(20.33± 8.92) (P<0.05)].The difference of VAS score was not significant between the two group (t=-1.49,P>0.05); while the difference of GSS score showed statistical difference between the two groups (t=-2.64,P<0.05).Conclusion Acupunctureon Yangchi point can effectively improve pain,numbness and motor activity in patients with the carpal tunnel syndrome.
2.Development of high-speed material handling machine based on field conditions
Ding SHEN ; Juming MA ; Guotong SU
Chinese Medical Equipment Journal 2004;0(09):-
According to the demand of combat readiness,a high-speed material handling machine based on field conditions is designed and manufactured to enhance the reaction and mobility of Mobile Medical Team.It is confirmed by the practice that this machine has such advantages as high efficiency,safety,convenience and easy maintenance.The difficulty of material handling in field conditions is solved.
3.Preliminary study of insulin resistance induced by neonatal monosodium glutamate treatment in normal Wistar rats
Shiying DING ; Zhufang SHEN ; Mingzhi XIE
Chinese Pharmacological Bulletin 2001;17(2):181-185
AIM To study the glucose and lipids metabolis m and insulin sensitivity of MSG rats during their growing period, and to evalua te the effects of insulin sensitizer pioglitazone on the model rats. MET HODS Body weights were measured regularly, and glucose and insulin tole rance tests were taken. In their 3 and 10 months old, rats were given insulin se nsitizer pioglitazone orally, then the effects on serum glucose, triglyceride, c holesteral, free fatty acid and insulin concentrations were determined. RESULTS Compared with normal rats, a slight but significant increase of glucose in MSG rats was revealed. The serum triglyceride, cholesteral, free fat ty acid and insulin concentrations were significantly higher in model rats. More over, gluconeogenesis increased significantly, and insulin tolerance showed abno rmal. However, glucose tolerance was nearlly normal. Pioglitazone could ameliora te all these metabolic disorders. CONCLUSION Obesity and insuli n resistance were induced by injecting monosodium glutamate (MSG) to neonatal Wi star rats. Pioglitazone can significantly improve the insulin sensitivity of MSG rats. These results suggested that MSG obese rats can be used as an easily acce ssible and inexpensive insulin resistance animal model for evaluating the effica cy and mechanisms of antidiabetic agents.
4."On Xu Lingtai’s ""Vitality"" Academic Thought"
Jing DING ; Wei WANG ; Jinzhan SHEN
Journal of Zhejiang Chinese Medical University 2013;(11):1291-1293
[Objective] To investigate doctor Xu Qing Lingtai’s vitality academic thought. [Methods] Using traditional philological research methods, through a careful reading medical books of Xu Lingtai, combined with various Chinese medicine theory, summarize his vitality academic thought. [Re-sult] The study refines that Xu Lingtaivitalityacademic thought can be summarized as: Xu thought vitality is the first righteous cause for doctors to treat diseases; doctors shal get to the bottom and care vitality. In theory, he viewed that the innate vitality comes before the blood and Qi. The true viscera essence is the sub-strength of vitality. In clinical thinking, he actual y applied the theory in 3 aspects:diagnosing diseases with vitality, evil and vitality com-bined and using warm-dry drugs with caution. [Conclusion] Xu Lingtai inherited the former based on the theory and put forwardstrength theory.Hisvitality theory is unique not only in the theory of traditional Chinese medicine essence, but also has great features in the clinical syndrome differentiation. Its doctrine has important reference value on clinical medicine.
5.Classic Hodgkin's lymphoma in post-treatment hairy cell leukemia: report of a case.
Chinese Journal of Pathology 2011;40(12):848-849
Aged
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Antibodies, Monoclonal, Murine-Derived
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therapeutic use
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Antineoplastic Combined Chemotherapy Protocols
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therapeutic use
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Bleomycin
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therapeutic use
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Dacarbazine
;
therapeutic use
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Doxorubicin
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therapeutic use
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Hodgkin Disease
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drug therapy
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pathology
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Humans
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Leukemia, Hairy Cell
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drug therapy
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pathology
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surgery
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Male
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Mitoxantrone
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administration & dosage
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Neoplasms, Multiple Primary
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drug therapy
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pathology
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surgery
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Rituximab
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Splenectomy
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Vidarabine
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administration & dosage
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analogs & derivatives
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Vinblastine
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therapeutic use
6.Expression of human interferon-?gene in colon cancer cell
Qiang DING ; Lizong SHEN ; Wenxi WU
Chinese Journal of General Surgery 2001;0(07):-
Objective This study was to investigate the expression of human interferon ?(huIFN ?) gene in colon cancer cells. MethodsThe whole length cDNA of huIFN ? was subcloned into the expression vector pcDNA 3 after sequence measurement. Lipofectamine was used to transfer huIFN ? gene into three colon cancer cell lines(LOVO?SW620?HCT116BG) .The integration and expression of huIFN ? were identified by PCR and RT PCR respectively, the activity of IFN ? expressed in different cell lines was measured by ELISA. Results PCR and RT PCR showed successful integration and sustained expression of huIFN ? in 3 colon cancer cell lines. Conclusion The huIFN ? can be effectively transduced into human colon cancer cells, and sustained expression was obtained.
7.In vitro effect of cytosine deaminase gene therapy and chemical reagents on colon cancer cell line
Lizong SHEN ; Qiang DING ; Wenxi WU
Chinese Journal of General Surgery 2001;0(07):-
ObjectiveTo evaluate the effect of combined cytosine deaminase(CD) gene therapy and chemical reagents on colon cancer cell line.MethodsLovo cells transducted with CD gene in a recombinant adenovirus AdCMVCD vector were treated with 5 fluorocytosine(5 FC) and ciplatin(CDDP) or mitomycine C(MMC). Cytotoxic effect was assayed with MTT method. ResultsLow dose of CDDP or MMC reduces the IC 50 of 5 FC significantly on Lovo cells transducted with CD gene and enhances the bystander effect of AdCMVCD/5 FC system.ConclusionCombined therapy with CD/5 FC system and chemical reagents may have a potential application in the treatment of colon cancer.
8.Relationship between lumbar discectomy outcomes and herniated type and annular integrity
Yong SHEN ; Baicheng CHEN ; Wenyuan DING
Chinese Journal of Orthopaedics 1998;0(12):-
Objective To analyse the relationship between lumbar discectomy outcomes and herniated type and annular integrity. Methods Two hundred and sixty patients who underwent conventional posterior discectomy for lumbar herniated disc were reviewed and followed-up for 6-14 years, with an average of 8.5 years. The criteria of enrolled patients include: all of the cases with low lumbar disc herniation at a single level, laterally protruded disc(one side sciatica) without spinal canal stenosis. Four categories of intraoperative findings were found basing on the defect size of annular and extruded fragments, and postoperative outcomes was compared statistically. Results The patients with larger disc fragments and minimal annular defects had the better outcomes and lowest incidence of recurrence after surgery. On the contrary, small fragments with massive annular defects did worse by comparison. Conclusion The outcomes of lumbar discectomy have close relationship with herniation type and annular integrity. Patients with mild clinical symptoms, small and broad-based disc herniations should be exempted from open discectomy. If open discectomy unavoidable, annular integrity and bony stability should be preserved as much as possible.