Objective To investigate the morphological difference of spinal single vertebral tuberculosis and metastasis by means of CT.Methods CT features of 16 cases of single vertebral tuberculosis and 17 cases of single vertebral metastasis which were proven by clinically and/or pathology, were retrospectively analyzed,and then the CT differential criteria of the two categories of diseases was recommended.Results The reliable CT findings for vertebral tuberculosis were as follows: involvement of anteriomedial potion of vatebral body,presence of sequstra in lesion ,marginal sclerosis in the edge of lesion,calcification within paravertebralmass or abscesses ,only edge enhancement of more of paravertebralmass.Metastasis was characterized by involvement of posteriomedial portion of vertebral bone,absence of sequestra within lesion ,no calcification within paravertebralmass.Both of them had normal intervertebral disc.Conclusion The different CT features of the single vertebral tuberculosis and metastasis are helpful in differerntiating diagnosis ,the morphological change of intervertebral discs is not helpful in differerntiating diagnosis .

Bile reflux is not only related to diseases such as gastritis,esophagitis,pharyngitis,chorditis,bronchitis and pneumonia,but also related to residual gastric ulcer,residual gastric cancer,intestinal metaplasia,dysplasia and carcinogenesis. Risk factors related to bile reflux include various operation modes, various anastomosis methods, gallbladder stone, cholecystectomy and various non-operative factors such as age, gender, allergy, mental and psychological factors,congenital factors. This article reviewed the advances in study on risk factors related to bile reflux.

Aged ; Humans ; Lung Diseases, Fungal ; complications ; microbiology ; Male ; Pneumoconiosis ; complications

Breast Neoplasms ; diagnosis ; genetics ; pathology ; Clinical Laboratory Techniques ; adverse effects ; trends ; Diagnostic Errors ; Female ; Genes, BRCA2 ; physiology ; Humans

Objective To study the levels of ? amyloid protein(A?/?A 4) in cerebrospinal fluid(CSF) of patients with Alzheimer's disease(AD) and vascular dementia(VD) and its significance of diagnosis.Methods The levels of A? 1 40 and A? 1 42 in CSF of 24 patients with AD, 14 patients with VD and 30 normal controls(NC) were detected by enzyme linked immunosorbent assays(ELISA).Results (1)The levels of A? 1 42 in CSF of AD and VD patients were significantly lower than NC group ( P

Objective To discuss the clinical value of intercostal arterial embolization for the treatment of hemoptysis.Methods A total of 91 patients with hemoptysis were enrolled in this study.Intercostal arterial embolization was performed using gelatin sponge.The patients were closely observed after the operation.For recurrent cases,re-embolization was carried out after identifying the causes of relapse.Results A total of 111 operations were performed on the 91 patients,including embolization of the bronchial and intercostal arteries in 74 cases,and simple embolization of the intercostal artery in 17.The rate of immediate hemostasis was 98.9%(90/91).The patients were followed up for 8 to 14 months,during which the recurrent rate was 15.4%(14/91).No serious complication occurred during the follow-up.Conclusion By embolizing both bronchial and intercostal arteries,the efficacy of the procedure can be increased and the rate the recurrence decreased,as long as proper measures have been taken to avoid serious complications.

Objective To evaluate the relationship between long-term survival rate and protection to marrow and lymphoid tissues in the pelvis with hypoxia radiotherapy for uterine cervical carcinoma. Methods 113 patients, confirmed as having carcinoma of uterine cervix by pathology, were randomly divided by the envelope method into two groups: hypoxia radiotherapy group(HRG,57 patients) and conventional radiotherapy group (CRG,56 patients). HRG was given by sustained inhaling hypoxia gas (oxygen physical volume=0.105) for two minutes before the start of radiotherapy till the end of radiotherapy of each field and then repeated for the other field in the same way. The duration of irradiation to each field was less than five minutes. CRG was given with conventional radiotherapy. The irradiation dose in the midpelvical plane was 20-50Gy depending on the different stages of cervical carcinomatous lesion. The dose of four-divided-field in the parametria was 15-34Gy.The dose at point A of intracavitary therapy was 15-35Gy. Results The decreased value of peripheral blood white cells after treatment was (1.36?1.27)?109/L in HRG and (2.97?1.19)?109/L in CRG(P

Objective To evaluate the effectiveness and safety of dexmedetomidine for the sedation of the patients after coronary artery bypass grafting (CABG).Methods The selective 96 CABG patients,ASA Ⅱor Ⅲ,aged 36 to 68 years old,58 males and 38 females,were randomly divided into 2 groups (n =48):dexmedetomidine group (group A) and midazolam group (group B).Group A patients received Dexmedetomidine (1.0 μg/kg)over 10 min,followed by 0.2-0.7 μg · kg-1 · h-1 to maintain sedation,whereas the other group patients received midazolam (0.05 mg/kg) over 10 min,followed by 0.02-0.10 mg · kg-1 · h-1 to maintain sedation.Two groups of patients stopped using drug when they were fit off-line and extubation.Observe the percentage of time within target sedative scope (Riker range 3-4),the changes of vital signs before and after treatment,the prevalence of delirium,the awakening time,the duration of mechanical ventilation,ICU length of stay,the adverse events of blood pressure and heart rate.Results There were no significant difference in the percentage of time within target sedative scope between two groups (75.5％ for dexmedetomidine group vs 74.6％ for midazolam group,P ＞ 0.05).Compared to midazolam group,the Dexmedetomidine group has a shorter awakening time [(14.0 ± 6.2) min for dexmedetomidine group vs (50.4 ± 12.8) min for midazolam group,P ＜ 0.05] and duration of mechanical ventilation,and also the prevalence of delirium was lower(15.3％ for dexmedetomidine group vs 34.6％ for midazolam group,P ＜0.05).ICU length of stay was similar.Dexmedetomidine-treated patients were more likely to develop bradcardia,with a non significant increase in the proportion requiring treatment,but had a lower likelihood of tachycardia or hypertension requiring treatment.Conclusion Dexmedetomidine is safe and effective in patients after CABG surgery.

Objective To investigate the effects of valsartan on the expression of acyl-coenzyme A: cholesterol acyltransferase-1(ACAT-1) and peroxisome proliferator activated receptor-gamma(PPAR-?) in atherosclerotic plaques on rabbit aortic wall.Methods Twenty-four male Japanese white rabbits were randomly assigned into three groups(8 each): control group,valsartan group and high cholesterol feeding group.All rabbits were fed according to the experimental protocol for 12 weeks.Blood samples were taken from vein for measurement of serum lipids.The ratio of intima/media thickness of the aorta was measured.ACAT-1 mRNA/protein and PPAR-? mRNA/protein were determined by reverse transcription polymerase chain reaction(RT-PCR) and Western blotting,respectively.Results After 12 weeks,the levels of serum total cholesterol(TC),triglyeride(TG) and low density lipoprotein-cholesterol(LDL-C) in valsartan group and cholesterol group were significantly higher than those in control group(P0.05).The intima thickness and the ratio of intima/media in carotid arteries in cholesterol group were significantly higher than those in control group and valsartan group(P

Objective To study the relationship between large multifunctional proteasome (LMP) 7 gene polymorphism and susceptibility of type 1 diabetes mellitus (DM). Methods The genotyping of LMP7 gene was determined by polymerase chain reaction restriction fragment length polymorphism (PCR RFLP) in 71 type 1 DM patients and 86 healthy persons (as controls). Furthermore, the type 1 DM patients were divided into 3 groups according to the age of diabetic onset. Group A was ≤14 years, group B 15～30 years, group C≥31 years.Results The frequency of LMP7 B/B was decreased significantly (39% vs 58%, P