1.Comparison of Outcomes and Costs of Transcatheter Therapeutic Intervention and Surgical Ligation for the Treatment of Patent Ductus Arteriosus.
Swee Chye QUEK ; Diana SANTOS ; Dimple Dayaram RAJGOR ; Fan YU ; Robert GRIGNANI
Annals of the Academy of Medicine, Singapore 2016;45(6):256-258
Adolescent
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Cardiac Catheterization
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economics
;
methods
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Child
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Child, Preschool
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Ductus Arteriosus, Patent
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surgery
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Female
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Health Care Costs
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Humans
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Infant
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Intensive Care Units
;
economics
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utilization
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Length of Stay
;
economics
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statistics & numerical data
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Ligation
;
economics
;
methods
;
Male
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Postoperative Complications
;
economics
;
epidemiology
;
Retrospective Studies
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Septal Occluder Device
;
economics
;
Singapore
;
epidemiology
;
Treatment Outcome
2.Patterns of herbal combination for the treatment of insomnia commonly employed by highly experienced Chinese medicine physicians.
Xue-zhong ZHOU ; Run-shun ZHANG ; Jatin SHAH ; Dimple RAJGOR ; Ying-hui WANG ; Ricardo PIETROBON ; Bao-yan LIU ; Jie CHEN ; Jian-gui ZHU ; Rong-lin GAO
Chinese journal of integrative medicine 2011;17(9):655-662
OBJECTIVETo explore the most effective herbal combinations commonly used by highly experienced Chinese medicine (CM) physicians for the treatment of insomnia.
METHODSWe collected and analyzed data related to insomnia treatment from the clinics of 7 highly experienced CM physicians in Beijing. The sample included 162 patients and 460 consultations in total. Patient outcomes, such as sleep quality and sleep time per day, were manually collected from the medical records by trained CM clinicians. Three data mining methods, support vector machine (SVM), logistic regression and decision tree, and multifactor dimensionality reduction (MDR), were used to determine and confirm the herbal combinations that resulted in positive outcomes in patients suffering from insomnia.
RESULTSResults show that MDR is the most efficient method to predict the effective herbal combinations. Using the MDR model, we identified several combinations of herbs with 100% positive outcomes, such as stir-fried spine date seed, Szechwan lovage rhizome, and prepared thinleaf milkwort root; white peony root, golden thread, and stir-fried spine date seed; and Asiatic cornelian cherry fruit with fresh rehmannia.
CONCLUSIONSResults indicate that herbal combinations are effective treatments for patients with insomnia compared with individual herbs. It is also shown that MDR is a potent data mining method to identify the herbal combination with high rates of positive outcome.
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Clinical Competence ; Data Mining ; Drug Therapy, Combination ; Drugs, Chinese Herbal ; therapeutic use ; Female ; Humans ; Male ; Medicine, Chinese Traditional ; Middle Aged ; Outpatients ; Physicians ; Sleep Initiation and Maintenance Disorders ; drug therapy ; Treatment Outcome ; Young Adult