1.A study on the liver dysfunction due to dimethylformamide.
Seong Kyu KANG ; Jae Yeon JANG ; Kyung Yong RHEE ; Ho Keun CHUNG
Korean Journal of Occupational and Environmental Medicine 1991;3(1):58-64
No abstract available.
Dimethylformamide*
;
Liver Diseases*
;
Liver*
2.A Study on the N-methylformamide Excretion Rate of Workers at Synthetic Leather Factories in Korea.
Ki Woong KIM ; Byung Soon CHOI ; Seong Kyu KANG ; Young Hahn MOON
Korean Journal of Occupational and Environmental Medicine 1999;11(1):106-112
This study was conducted to examine the excretion rate of dimethylformamide (DMF) from the workers exposed to DMF. The study was done at two synthetic leather factories located in Kyeonggi-do from the period of May 2 to 30, 1996. N-methyl- formamide (NMF) concentrations in urine were measured and compared by the three exposure level of DMF in air. The mean concentration of the Low (dry and winder part). Moderate (rinsing part) and High (mixing and coating part) exposure group were 3.99+/-3.54. 10.19 +/-5.69 and 32.10+/-7.87 mg/m3 during workshift of 8 hours, respectively. The mean concentration of urinary N-methylforinamide (NMF) were 2.13+/-2.58, 11.16+/-4.98 and 26.24 +/-7.35 mg/g creatinine, respectively. The concentration of NMIF in urine could reach to maximum in 3 hours and was reduced nearly to zero in about 18 hours after exposure to DMF.
Creatinine
;
Dimethylformamide
;
Environmental Monitoring
;
Gyeonggi-do
;
Korea*
5.Seasonal Variations of the Urinary N-Methylformamide Concentration among Workers at a Synthetic Leather Factory.
Kwang Young LEE ; Joo Hyun BYEON ; Hae Rhan SONG ; Jin Ha KIM ; Kwang Wook KO ; Yong Hwan LEE
Korean Journal of Occupational and Environmental Medicine 2003;15(2):162-172
OBJECTIVES: This study was carried out to identify seasonal variations of urinary concentrations of N-methylformamide (NMF) among workers employed at a synthetic leather factory. METHODS: Study subjects consisted of 16 male and 6 female workers who were involved in the direct treatment of dimethylformamide (DMF) in a synthetic leather factory. By using health examination data and the results of air measurements and biologic monitoring conducted in February and July, 2001, we identified seasonal variations of the DMF concentrations in the air and NMF concentrations in urine. RESULTS: 1) In winter and summer, average temperatures at the working sites were 3.2 degrees C and 26.5 degrees C, respectively and average humidities were 35.4 % and 84.5 %, respectively. 2) Airborne DMF concentrations were not significantly different between summer (13.78 ppm) and winter (11.55 ppm). 3) NMF concentrations in urine were found to be significantly higher in summer (96.09 mg/g creatinine) than in winter (31.23 mg/g creatinine) (p<0.001). CONCLUSIONS: The seasonal difference in the urinary excretion values of NMF may be due to increased dermal absorption of DMF with the higher ambient temperature and humidity in summer and the increased area of exposed skin.
Absorption
;
Dimethylformamide
;
Environmental Monitoring
;
Female
;
Humans
;
Humidity
;
Male
;
Seasons*
;
Skin
Result Analysis
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