Objective To observe the effect of artificial tears in the treatment of xerophthalmia after cataract surgery with phacoemulsification combined with intraocular lens implantation.Methods 384 patients with 384 xerophthalmia eyes after cataract surgery with phacoemulsification combined with intraocular lens implantationwere selected.They were randomly divided into observation group and control group,192 eyes in each group.Conventional therapy was given in the control group,and artificial tears was added in the observation group.The SIT,FL,BUT and adverse reactions were observed and compared.Results There were improvement of SIT,FL and BUT in both two groups after treatment.The SIT (mm/5min)in the observation group was (13.97 ±1.72),that was (9.12 ±1.02) in the control group,the improvement of SIT in the observation group was better than the control group (t =2.942, P <0.05).The FL (s)in the observation group was (2.06 ±0.37),that was (3.71 ±0.72)in the control group, the improvement of SIT in the observation group was better than the control group (t =1.776,P <0.05).The BUT (s)in the observation group was (13.26 ±2.04),that was (7.99 ±2.16)in the control group,the improvement of BUT in the observation group was better than the control group (t =4.098,P <0.05).There were 39 cases of healing eyes in the observation group,and healing rate was 27.46%.There were 21 cases of healing eyes in the control group, the healing rate was 14.79%.The healing rate in the observation group was higher than the control group (χ2 =7.748,P <0.05 ).There were 183 cases of effective treated eyes in the observation group,the effective rate was 93.66%,and there were 120 cases of effective treated eyes in the control group,the effective rate was 84.51%.The effective rate in the observation group was higher than the control group (χ2 =7.094,P <0.05).Conclusion It is effective to apply artificial tears in the treatment of xerophthalmia after cataract surgery with phacoemulsification com-bined with intraocular lens implantation and safe.It is worthy of clinical application.