1.Predictive models and prophylactic strategies for anastomotic leakage in colorectal surgery.
Chinese Journal of Gastrointestinal Surgery 2022;25(11):987-991
Anastomotic leakage (AL) has always been a persistent issue for colorectal surgeons. It is still difficult to reduce the incidence of AL despite the advances in technology and equipment. With the development of evidence-based medicine, increasing high-risk factors for AL have been identified. How to efficiently and systematically combine and quantify these isolated risk factors to provide a scientific early warning of AL in clinical practices and help surgeons in choosing the optimal prophylactic strategies, is of great significance for reducing the incidence of AL. There are generally two types of AL prediction models in colorectal surgery, including prognostic models (for preoperative and intraoperative AL prediction) and diagnostic models (for early warning and improving the early diagnosis rate of AL). Prophylactic strategies for AL include stabilizing the underlying diseases, improving anemia and hypoalbuminemia, choosing an appropriate operative time window, and emphasizing and improving anastomotic techniques (including choosing an appropriate size of stapler). However, a prophylactic ostomy is still the most common method for surgeons. However, how to reduce the morbidity of complications following prophylactic ostomy and how to avoid the conversion of the prophylactic stoma to permanent stoma need further study.
Humans
;
Anastomotic Leak/etiology*
;
Colorectal Surgery/adverse effects*
;
Digestive System Surgical Procedures/adverse effects*
;
Anastomosis, Surgical/methods*
;
Risk Factors
2.The Quality of Life after Rectal Cancer Surgery.
The Korean Journal of Gastroenterology 2006;47(4):295-299
Surgery is a definite treatment for rectal cancer by resecting the tumor. Surgeon not only aims to cure the patient but aims to relieve distressing symptoms as well. Unfortunately, patients may suffer adverse consequences from such surgery. The operative dissection of the rectum may damage the pelvic autonomic nerves disturbing bladder and sexual function. The construction of a permanent colostomy following an abdominoperineal resection may be associated with one or more physical problems as well as clinically significant psychosocial problems as well. The advances in knowledge of tumor biology and the improvements of surgical techniques and devices result in an increasing number of sphincter saving procedures such as low anterior resection. Although avoiding permanent stoma is generally regarded as a favorable outcome measure, patients undergoing sphincter-saving surgery may develop a number of unpleasant symptoms, typically fecal soiling and urgency, especially with low anastomosis. It is evident that the consequences of rectal surgery have an important bearing on quality of life. Although differences in definition exist, quality of life may be regarded as representing an individual's ability to carry out daily activities, as well as satisfaction with personal performance and with balance between disease control and adverse effects of treatment. In addition to traditional endpoints, such as survival and disease recurrences, assessing quality of life is necessary to provide a proper, comprehensive understanding of the outcome of surgery and other forms of treatment.
Digestive System Surgical Procedures/adverse effects
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Humans
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Postoperative Complications
;
*Quality of Life
;
Rectal Neoplasms/*surgery
3.Research advance in causes of postoperative gastrointestinal dysfunction.
Shanjun TAN ; Guohao WU ; Wenkui YU ; Ning LI
Chinese Journal of Gastrointestinal Surgery 2016;19(3):351-355
Gastrointestinal dysfunction is a common and major complication after surgery. The syndrome covers a wide spectrum of clinical signs, ranges from mild feeling to severe discomfort and varies from person to person. The mild patients need no care, but severe ones may have long hospital stay, and even suffer from multiple organ dysfunction syndrome, severely affecting postoperative rehabilitation. However, the etiology of postoperative gastrointestinal dysfunction has not been fully elucidated. Much research demonstrates that many factors, such as operative procedures, surgical operation, homeostasis disturbance, anesthesia and analgesia, blood perfusion, inflammation, and neuroendocrine factors, are responsible for the development and progression of postoperative gastrointestinal dysfunction. This study therefore reviewed the causes of postoperative gastrointestinal dysfunction in the published literatures.
Digestive System Surgical Procedures
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adverse effects
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Gastrointestinal Tract
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physiopathology
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Humans
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Postoperative Complications
;
Postoperative Period
4.Prevention and treatment of postoperative complications following gastrointestinal surgery.
Chinese Journal of Gastrointestinal Surgery 2012;15(4):313-316
Gastrointestinal cancers include gastric cancer, small intestinal cancer and colorectal cancer. In China, the majority of hospitals at central cities even at county hospitals are providing surgical intervention for patients with gastrointestinal cancer. However, the complications after gastrointestinal cancer surgery pose significant burden to the patients and their relatives because of increased hospital cost and law suit. Acute bleeding, obstruction, anastomotic leakage are major complications after gastrointestinal surgery. Therefore it is important to deal with complications after gastrointestinal surgery.
Digestive System Surgical Procedures
;
adverse effects
;
Gastrointestinal Neoplasms
;
surgery
;
Humans
;
Postoperative Complications
;
prevention & control
;
therapy
5.Progress in diagnosis and treatment of gastroparesis after colon cancer surgery.
Zhi Zhong PAN ; Long YU ; Jian Hong PENG
Chinese Journal of Gastrointestinal Surgery 2022;25(6):558-562
At present, comprehensive treatment dominated by surgical procedures is an important measure for colon cancer to obtain the chance of cure. Surgical intervention, while removing the tumor, carries the risk of postoperative gastroparesis (PG) . Because of the low incidence rate and insignificant early clinical symptoms, early stage PG is often overlooked clinically. However, PG can increase the risk of malnutrition, delay postoperative antitumor treatment, and increase the risk of tumor recurrence and metastasis. This review focuses on the mechanisms, clinical risk factors, preventive measures, and advances in treatment of PG due to colon cancer. Aim to increase the clinician's adequate attention to PG in colon cancer and from a surgical point to reduce the risk of gastroparesis in colon cancer by optimizing the surgical strategy.
Colonic Neoplasms/surgery*
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Digestive System Surgical Procedures/adverse effects*
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Gastroparesis/therapy*
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Humans
;
Neoplasm Recurrence, Local
6.Chinese expert consensus on transanal drug administration for constipation (2022 edition ).
Chinese Journal of Gastrointestinal Surgery 2022;25(12):1058-1064
Constipation is a clinical symptom. It can be caused by environment, habit, disease and drugs. Chronic constipation is a disease that can occur at any age and its prevalence increases with age. Transanal administration is a common method to treat all kinds of constipation, especially to relieve stool blockage. However, the method and dose of transanal administration vary by age, drug and preparation types of drugs, and the effect of defecation is also quite different. At present, there is no expert consensus to follow in China or abroad. This consensus was convened by Anorectal Branch of Chinese Medical Doctor Association, Colorectal Surgery Group of Branch of Surgery of Chinese Medical Association and Chinese Journal of Gastrointestinal Surgery, to incorporate the latest evidence in China and abroad. This consensus addressed common transanal preparations, principles of administration, and efficacy for constipation. The evidence quality was assessed and the recommendation intensity was graded according to the GRADE system. The consensus aims to help standardize drug selection in practice and guide clinical application.
Humans
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Consensus
;
East Asian People
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Constipation/etiology*
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Feces
;
Digestive System Surgical Procedures/adverse effects*
7.Establishment and data quality control of a multicenter prospective database for prevalence of abdominal complications after gastroenterological surgery.
Qi WANG ; Zhou Qiao WU ; Zi Ning LIU ; Zi Yu LI ; Jia Fu JI
Chinese Journal of Gastrointestinal Surgery 2023;26(2):154-159
As the main cause of secondary operation and postoperative death, the incidence of intraperitoneal infectious complications varies significantly in different medical centers in China. Due to the lack of national data, it is not possible to assess and develop appropriate diagnosis and treatment strategies properly. To provide a high-quality data platform for complication registration and clinical research, a multicenter prospective database for the Prevalence of Abdominal Complications After GastroEnterological surgery was established. Based on the Hospital Information System (HIS)of 20 medical centers in China, the electronic case reporting form (e-CRF) listed on the website was used to collect medical information of patients undergoing gastric or colorectal cancer surgery. The data were verified by on-site auditing, and data cleaning was performed by R software. After the data cleaning, the data in the database was checked and evaluated by the principle investigators and data administrators. When all data queries and questions were corrected and answered, the database was locked to establish a multicenter prospective database for postoperative abdominal infectious complications (the PACAGE database). The PACAGE database has rich information resources and high data quality and is a good data platform for complication registration and clinical research.
Humans
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Prevalence
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Data Accuracy
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Postoperative Complications/etiology*
;
Abdomen/surgery*
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Digestive System Surgical Procedures/adverse effects*
8.Current practice in the prevention and management of surgical site infections in gastrointestinal surgery.
Chinese Journal of Gastrointestinal Surgery 2012;15(6):533-536
Surgical site infection(SSI) is one of post-operative complications in gastrointestinal surgery. SSI may increase the morbidity and mortality of surgical patients and increase their hospital stay and expense. The risk factors can come from patients, physicians and hospital environments. Improving patients nutritional status and organ function, appropriate control of blood sugar level and abstinence from smoking can reduce the occurrence of SSI. Compare to current practice in China, the following recommendations have been identified as priorities for implementation: hair removal done immediately before operation; maintenance of normothermia intraoperatively; the abdominal wall should be closed with an absorbable suture and drains should be removed as early as possible. SSI could be diagnosed by symptoms, local signs and lab examinations and confirmed by physician. Source control is the key point in the management of SSI. Ultrasound and CT guided percutaneous abscess drainage is effective in the localized deep space surgical site infection and critically ill patients. Antibiotics should be used following clinical assessment and evidence based on local formulary.
Digestive System Surgical Procedures
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adverse effects
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Humans
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Infection Control
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Risk Factors
;
Surgical Wound Infection
;
diagnosis
;
etiology
;
prevention & control
;
therapy
9.Prevention and management of anastomotic bleeding after laparoscopic anterior resection of rectal cancer.
Chinese Journal of Gastrointestinal Surgery 2016;19(4):383-385
In recent years, the laparoscopic anterior rectal cancer resection is increasingly applied in clinical practice, however, laparoscopic operations and stapling techniques can bring a series of related complications. The anastomotic bleeding is one of the early complications in laparoscopic anterior rectal cancer resections. If the continuous anastomotic bleeding is not diagnosed or managed in time, it could lead to serious consequences, such as secondary surgery and shock. Therefore, the diagnosis and treatment of anastomotic bleeding is meaningful. This paper investigates the reasons of anastomotic bleeding after laparoscopic anterior resection of rectal cancer, and introduces related preventions and treatments. Conservative treatment can be used first for small or delayed bleeding. As for acute bleeding from low anastomosis, transanal suture hemostasis can be considered. When the bleeding comes from high anastomosis and is massive and active, laparoscopic or open surgery must be performed immediately.
Anastomotic Leak
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prevention & control
;
surgery
;
Digestive System Surgical Procedures
;
adverse effects
;
Hemorrhage
;
Humans
;
Laparoscopy
;
Rectal Neoplasms
;
surgery
10.Prevention and management of postoperative complications in patients with inflammatory bowel disease.
Xianrui WU ; Xuanhui LIU ; Ping LAN
Chinese Journal of Gastrointestinal Surgery 2016;19(4):370-375
The incidence of inflammatory bowel disease in China is rising on a yearly basis, followed by an increased number of patients who require surgery and those who suffer from maneuver postoperative complications. Surgical treatment is important in the management of patients with inflammatory bowel diseases. Management and prevention of postoperative complications is also a key factor to the success of surgical treatment if it is not more important than the surgical procedure itself. In this article, the most recent literatures in this field will be reviewed combined with our own clinical experiences. The types, risk factors, preoperative prevention strategies as well as postoperative management of surgical complications of patients with inflammatory bowel disease will be discussed.
China
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Digestive System Surgical Procedures
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adverse effects
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Humans
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Incidence
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Inflammatory Bowel Diseases
;
surgery
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Postoperative Complications
;
prevention & control
;
therapy
;
Risk Factors