Using the full quadratic model in drug dissolution optimization, the authors built up the sustained release of diclofenac tablet formulation with hydrophilic matrix excipient. The sustained excipient releases xanthan gum which has good features such as controlling medical substance regularly, rubbing seed easily, covering tablet easily and compressed force with a little affect to the rate of medical substance release. This formulation can be applied in making up medicines with a wider scale. It is being tested its stability and evaluated its availability to apply in manufacture
Diclofenac, Pharmaceutical Preparations , Tablets