Using same TDE factors, the authors studied the effects of whole abdominal irradiation on body weight and peripheral blood picture in 30±3 day old mice. Fractions of 100 and 200 cGy were given five times a week to the final TDF factors 17, 33, and 49. Total 80 mice were irradiated with orthovoltage x-ray machine. Our results can be summarized as follows: There were no significant differences by sex. Body weight was progressively decreased by the duration for irradiation, but no remarkable difference by fractional dose. Hemoglobin level showed no remarkable change by fractional dose or TDF factors. Leukopenic changes showed that severity of decrease seems to be more related to TDF factors. There were no significant changes of differential count by TDF factors of total doses.
Animals ; Body Weight* ; Dichlorodiphenyldichloroethane ; Mice*

BACKGROUND AND OBJECTIVES: The optimal AV delay should allow for the completion of the atrial contraction prior to the ventricular contraction, and provide for the longest diastolic filling and maximal stroke volume. This study evaluated the effects of the AV delay on the changes in heart functions, in patients with a DDD pacemaker and normal systolic function. SUBJECTS AND METHODS: Nineteen patients were enrolled. The pacing rate was set at 70 beats/min. The AV delay was lengthened in 20-25 msec step, from 100 to 250 msec. The stroke volume and diastolic parameters were measured by echocardiography for each AV delay. RESULTS: The changes in the stroke volume associated with the changes in the AV delay were not statistically significant. However, when viewing each individual patient, the optimal AV delay for each patient could be found. When comparing the stoke volumes obtained just before, just after, and during the maximal AV delay, a statistically significant difference was found (p< 0.05). The absolute value of the E/A ratio was less than 1. The pulmonic vein flow pattern was dominated by the systolic flow, but the changes were not statistically significant. There was a tendency for the E wave propagation slope to decrease. However, the absolute value was less than 40 cm/s, and the E/E' absolute ratio was more than 8, but neither showed any significant differences. CONCLUSION: In patients with a DDD pacemaker and normal systolic function, the diastolic parameters were abnormal, and the stroke volume affected by the change in the AV delay.
Diastole ; Dichlorodiphenyldichloroethane* ; Echocardiography ; Heart ; Humans ; Stroke Volume ; Veins

BACKGROUND: Recently, the 2nd generation IPL with a filtered xenon flash lamp has been widely used in the dermatologic field. In disagreement with the manufacturer's intent, for Asian skin, there were some reports that the best results for vascular lesions were obtained with the PR applicator, while the best results for pigmented lesions were obtained with the VL applicator. OBJECTIVE: The purpose of this study is to compare the efficacy and safety of two different (530~750 nm PR applicator and the 555~950 nm VL applicator) wavelength bands of 2nd generation IPL in Korean photo-rejuvenation. In addition, we compared the improvement of telangiectasia, irregular pigmentation, and overall patient' satisfaction for both settings. METHODS: Twenty-two patients with signs of photoaging skin including irregular pigmentation and telangiectasia were treated with 2nd generation IPL (Ellipse-Flex(R), DDD, Denmark) using a split-face comparative method, comparing both sides with respect to improvement of telangiectasia, irregular pigmentation, and overall patient satisfaction. RESULTS: Comparison of the efficacy and safety between the VL and PR applicators revealed that the VL applicator was not specific for vascular lesions and that the PR applicator was not specific for pigmented lesions. Additionally, VL is not better than PR for vascular lesions (p=0.80, McNemar test) and PR is not better than VL for pigmented lesions (p=0.80, McNemar test). Finally, improvements in skin texture were not significantly different between VL and PR (p=0.80, McNemar test). CONCLUSION: The two IPL wavelength bands were found to be effective in the treatment of photo-damaged facial skin. The difference between the two treatment procedures with regard to clinical efficacy and safety was not significant.
Asian Continental Ancestry Group ; Dichlorodiphenyldichloroethane ; Humans ; Pigmentation ; Skin ; Telangiectasis ; Xenon

A thorough knowledge about the branching variations of the femoral and deep femoral arteries is important in vascular reconstructive surgery of the proximal leg. The present study was done to describe the patterns of origin of the main branches of the femoral and deep femoral arteries in Koreans. The cadavers of 77 Koreans(male, 51 ; female, 26), who were 18-97 years old of time of death, were used in the present investigations and the femoral arteries of 152 sides(right side, 77 ; left side, 75) were observed. The femoral arteries of two left sides were excluded from this study because their branches were not clearly examined during dissection. The results were as follows : 1. Lateral circumflex femoral artery arose from the deep femoral artery in 78.9% and from the femoral artery in 21.1%. Significant differences between the right and left sides were not observed. 2. Medial circumflex femoral artery arose from the deep femoral artery in 77.0% and from the femoral artery in 22.4%. This artery arose more frequently from the femoral artery on the left side, and from the deep femoral artery on the right side in about a 9-10% differential respectively. In one case, the medial circumflex femoral artery arose from the lateral circumflex femoral artery on the left side. 3. The descending branch, which is normally a branch of the lateral circumflex femoral artery, arose from either the femoral or the deep femoral arteries in about 7% of the cases respectively. 4. The patterns of origin of the deep and circumflex femoral group of arteries were classified into 18 types. Each type is represented in three letters by using the initial of the deep femoral artery (D) or femoral artery (F) or lateral circumflex femoral artery (L) in the order of origin of the lateral circumflex femoral artery, medial circumflex femoral artery and descending branch. Types DDL(49.3%), FDL(18.4%) and DFL(15.1%) constituted the three major types on both sides. In addition, seven types (DFD, FFL, DDD, DDF, DFF, DLL and FDF) were found on the left side and three types (DDF, DDD and DFD) on the right side.
Adult* ; Arteries ; Cadaver ; Dichlorodiphenyldichloroethane ; Female ; Femoral Artery* ; Humans ; Leg

Pacemaker-mediated tachycardia(PMT) is a circus movement tachycardia that can occur in patients with dual chamber pacemaker with atrial sensing(VDD or DDD), when a ventricular depolarization, either spontaneous or paced, causes retrograde activation of the atrium. Recently, a number of pacemaker manufactures have incorporated in their devices a variety of relatively complex algorithms to prevent PMT. Despite these measures, PMT may still occur because of inappropriate programming or unpredictable variations of ventriculoatrial conduction. We report one case of PMT in a 78-year-old male who received DDD type pacemaker due to sick sinus syndrome. In this case, PMT was disappeared after reprogramming parameters of pacemaker and the application of PMT protection algorithm.
Aged ; Dichlorodiphenyldichloroethane ; Humans ; Male ; Sick Sinus Syndrome ; Tachycardia*

Therapeutic ionizing radiation can damage the permanent pacemaker. Reimplantation of pacemaker should be considered when the pacemaker site is included in the radiation field. We report a case of successful repositioning of preexisting pacemaker generator and leads with subcutaneous tunneling method across the sternum instead of insertion of new leads in a female patient with breast cancer who had DDD pacemaker.
Breast Neoplasms ; Dichlorodiphenyldichloroethane ; Female ; Humans ; Radiation, Ionizing ; Replantation ; Sternum

OBJECTIVE: The authors conduct a retrospective study to evaluate the efficacy of anterior lumbar interbody fusion(ALIF) in treating degenerative disc disease(DDD) and degenerative spondylolisthesis(DS). METHODS: During 1998, eighty-six patients underwent mini-retroperitoneal ALIF with Brantigan carbon cages. Among them, 19 patients were lost during the follow-up period and 23 patients underwent multilevel fusion procedures. The authors evaluated 44 single-level cases(31 with DDD; 13 with DS) with Macnab's criteria for clinical outcomes and the Criteria of Brantigan and Steffee for fusion results. The extent of slippage of patient with DS was not greater than grade 1. The mean follow-up period was 24 months. RESULTS: The overall fusion rate was 88.6%(94% in DDD; 77% in DS). Based on the Macnab's criteria, excellent or good results were achieved in 38 of 44 patients(86.3%). Overall clinical outcome was significantly associated with preoperative diagnosis(p=0.03), radiologically demonstrated fusion(p=0.001), and subsidence of cages(p=0.03). In DDD sub-group, two cases of fusion failure and four of subsidence of cages belonged to excellent or good results. But, in DS sub-group, fusion failure or subsidence rate were significantly high and all three cases with poor result belonged to this sub-group. One of them underwent posterior operation. CONCLUSION: ALIF is considered as a good surgical method for a patient with discogenic back pain caused by degenerative disc disease. But in degenerative spondylolisthesis, considering the comparatively poor clinical and radiological result, it seems that ALIF alone does not provide sufficient strength to overcome the instability. Despite the advantage of minimal invasiveness, more careful application of ALIF is needed in the of degenerative spondylolisthesis.
Back Pain ; Carbon ; Dichlorodiphenyldichloroethane ; Follow-Up Studies ; Humans ; Retrospective Studies ; Spondylolisthesis*

BACKGROUND AND OBJECTIVES: Dual-chamber pacing is commonly used as a pacing mode maintaining at-rioventricular synchrony. However, traditional technique for atrial J lead implantation is relatively time-consuming and not easy to get optimal sites for both atrial and ventricular leads, especially for less-experienced operators. We developed a new "push technique" for atrial J lead implantation. MATERIALS AND METHOD: This study included sixty-two consecutive patients (26 males 36 females, 55+/-10 years, 56 patients received DDD and 6 received AAI pacemakers) from Jan. 1992 through Dec. 1996. Atrial J leads were implanted using a "push technique", that is, simply advancing a straightened lead while holding the stylet in the pacing lead at the junction of the superior vena cava and the right atrium. We evaluated the early and long-term result of atrial J lead implantation by the "push technique". RESULTS: 1) Atrial leads were successfully inserted by the first or second trial of the "push technique" in the 62 patients (100%). The sensed P wave amplitude was 3.1+/-1.0 mV, pacing threshold 0.6+/-0.2 V at the pulse width of 0.5 ms, impedance 547.4+/-118.5 ohms at 5 V. 2) During follow-up of 28.1+/-15.7 months, significant changes in the pacing parameters and the dislodgement of atrial leads were not seen. CONCLUSION: The early and long-term result of atrial J lead implantation by the "push technique" was excellent. This "push technique" can be used as an easy alternative technique for atrial J lead implantation.
Dichlorodiphenyldichloroethane ; Electric Impedance ; Female ; Follow-Up Studies ; Heart Atria ; Humans ; Male ; Vena Cava, Superior

OBJECTIVE: This consecutive retrospective study was designed to analyze and to compare the efficacy and outcomes of anterior cervical discectomy and fusion (ACDF) using a fibular and femur allograft with anterior cervical plating. METHODS: A total of 88 consecutive patients suffering from cervical degenerative disc disease (DDD) who were treated with ACDF from September 2007 to August 2010 were enrolled in this study. Thirty-seven patients (58 segments) underwent anterior interbody fusion with a femur allograft, and 51 patients (64 segments) were treated with a fibular allograft. The mean follow-up period was 16.0 (range, 12-25) months in the femur group and 19.5 (range, 14-39) months in the fibular group. Cage fracture and breakage, subsidence rate, fusion rate, segmental angle and height and disc height were assessed by using radiography. Clinical outcomes were assessed using a visual analog scale and neck disability index. RESULTS: At 12 months postoperatively, cage fracture and breakage had occurred in 3.4% (2/58) and 7.4% (4/58) of the patients in the femur group, respectively, and 21.9% (14/64) and 31.3% (20/64) of the patients in the fibular group, respectively (p<0.05). Subsidence was noted in 43.1% (25/58) of the femur group and in 50.5% (32/64) of the fibular group. No difference in improvements in the clinical outcome between the two groups was observed. CONCLUSION: The femur allograft showed good results in subsidence and radiologic parameters, and sustained the original cage shape more effectively than the fibular allograft. The present study suggests that the femur allograft may be a good choice as a fusion substitute for the treatment of cervical DDD.
Dichlorodiphenyldichloroethane ; Diskectomy ; Femur ; Follow-Up Studies ; Humans ; Neck ; Retrospective Studies ; Stress, Psychological ; Transplantation, Homologous

BACKGROUND: The development of techniques and improvement of diagnostic facilities have led to the increased use of pacemakers in cardiac patients. So, anesthesiologists should have paid more attention to the patients with pacemakers, and they also need the full knowledge of wide varieties of pacemakers currently used for a safety of these patients. The purpose of this study is the assessment of fifteen pacemaker patients undergoing surgery. METHODS: This study was done in 15 cardiac patients with pacemaker who underwent noncardiac operations. We evaluated symptom, ECG rhythm, underlying cardiac disease before pacemaker implantation and the type of implanted pacemaker. The type and duration of operations, together with anesthetic techniques were also assessed. RESULTS: The pre-pacemaker symptoms were intermittent dizziness, palpitation, syncope, and general weakness. The underlying cardiac diseases were complete A-V block, sick sinus syndrome and bifascicular block. The types of implanted pacemakers were VVIR (n=14) and DDD (n=1). The kinds of anesthetic techniques were general anesthesia (N2O-O2-enflurane; n=10, N2O-O2-fentanyl; n=1), and continuous epidural block (n=3) or continuous spinal block (n=1) combined with general anesthesia (N2O-O2). CONCLUSIONS: We should evaluate the patient with pacemakers preoperatively for underlying cardiac disease and implanted pacemaker. Thereafter, we have to choose the safe anesthetic technique.
Anesthesia, General ; Dichlorodiphenyldichloroethane ; Dizziness ; Electrocardiography ; Heart Diseases ; Humans ; Sick Sinus Syndrome ; Syncope