No abstract available.
Diazepam* ; Seizures, Febrile*

No abstract available.
Diazepam* ; Seizures, Febrile*

The hypnotic activity of diazepam was compared with that of inactive placebo in a double- blind, randomized study in 40 surgical patients the night before their scheduled procedures. Diazepam per os (10mg) produces a pattern of response that differed markedly from that of the placebo. The patient receiving diazepam fell asleep sooner, slept more soundly and steadily and more felt they had been helped to sleep, while fewer awoke during the night. The significant difference Was obtained in both hypnotic and ataractic effects between diazepam and inactive placebo. Neither diaxepam nor inactive placbo caused marked changes in vital signs or any serious side effects.
Diazepam* ; Humans ; Vital Signs

OBJECTIVE

This study aimed to determine whether adjunctive therapy with magnesium sulfate is more effective than diazepam alone in reducing mortality and morbidity rates among adult patients with tetanus admitted to Mariano Marcos Memorial Hospital and Medical Center (MMMH & MC) from January 1, 2012, to January 1, 2022.

Retrospective cohort study using chart review and descriptive statistics. included patients admitted at East Avenue Medical Center for DFU. The primary endpoint was major amputation of the lower extremities. Data were analyzed using Receiver Operating Characteristic (ROC) analysis and logistic regression.

A total of 51 patients were included in the study, with 17 patients in the adjunct magnesium sulfate group and 34 patients in the diazepam group. Based on the results of this study, at a 95% confidence interval, ICU stay was significantly longer in the magnesium sulfate group compared to the diazepam group, along with an increased average hospital stay. There was no significant difference in patient mortality in terms of treatment, age, severity, ICU stay, or duration of mechanical ventilation.

The use of magnesium sulfate as an adjunct treatment for tetanus is not superior to standard stand-alone diazepam, regardless of severity. Magnesium sulfate use is associated with a longer overall hospital stay. Lastly, hospital-acquired pneumonia and aspiration pneumonia significantly increase the risk of mortality among patients with tetanus, regardless of age, treatment, or severity.

No abstract available.
3,4-Dihydroxyphenylacetic Acid* ; Animals ; Brain* ; Diazepam* ; Rats*

The purpose of this study was to define the optimum dose of lidocaine required to reduced pain on injection of diazepam. We conducted a prospective, randomized trial on l20 patients undergoing anesthesia. patients were allocated to four groups according to the lidocaine do sage: group A(control), no lidocaine; group B, lidocaine 0.1 mg/kg; group C, lidocaine 0.2 mg/kg; group D, lidocaine 0.4 mg/kg. our results sbowed that a dose of lidocaine 0.4 mg/kg significa ntly reduced the incidence of pain.
Anesthesia ; Diazepam* ; Humans ; Incidence ; Lidocaine* ; Prospective Studies

No abstract available.
Diazepam* ; Humans ; Hypnotics and Sedatives* ; Midazolam* ; Surgery, Plastic*

No abstract available.
Diazepam* ; Hemodynamics* ; Morphine* ; Pancuronium* ; Respiration, Artificial*

In view of the current trend towards carrying out termination of pregnancy as day cases it is also important that the patient should be free from pain with a rapid recovery from anesthesia and a minimum of post operative sequalae. We compared the effects of three other anesthetic techniques for the termination of pregnancy in 100 healthy womes as day cases. 1) Anesthesia with thiopental sodium alone was associated with a high score of pain sensation(2+/-0.93) and with considerably rapid recovery(103+/-57.6 mins). 2) The combination of thiopental sodium and meperidine was associated with a lower score of pain sensation(1.58+/-0.8) and with rapidl recovery(101+/-56.4 mins). 3) Meperidine with diazepam was associated with the lowest score of pain sensation(1.4+/-0.69), but had prolonged recovery time(206+/-126 mins) twice that of other techniques. It was conclued that the combination A thiopental sodium and meperidine was the technique of choice for termination of pregnancy as day-cases.
Anesthesia ; Diazepam ; Humans ; Meperidine ; Pregnancy* ; Thiopental

The influence of the intravenous injection of single-dose diazepam on plasma potassium, sodium and chloride concentions was studied in 36 healthy patients undergoing minor surgical operations and this investigation was limited to the first 10 minutes after the intravenous injection of diazepam, 10mg. A significant decrease of plasma potassium concentration(-0.24 ~ -0.25 mEq/1) was observed with diazepam at 5 and 10 minutes but the diazepam investigated in this study did not have a significant effect on the plasma sodium and chloride.
Diazepam* ; Humans ; Injections, Intravenous* ; Plasma* ; Potassium* ; Sodium*