1.The Effects of Aerobic Exercises on the Pulmonary Ventilation Function and Electrocardiac Activity of Simple Obesity Primary School Students
Guoxiang WANG ; Dianyu LIU ; Wenjun WANG ; Chunlin YUE
Chinese Journal of Sports Medicine 2010;(2):170-172,169
Objective To investigate the effects of aerobic exercises on the pulmonary ventilation function and electrocardiac activity of simple obesity primary school students. Methods 30 simple obesity boy students were recruited for this study. All the subjects participated in a 12-week aerobic training program (40 min/day,4 days/week). Body composition,pulmonary function and electrocardiogram were tested at the beginning and the end of the training program. Results Decreases of fat mass and body fat ratios were found in response to the exercise stimulus (P<0.05). Free-fat mass(FFM) significantly increased. No statistically significant differences of waist hip ratio (WHR) were found. Among the pulmonary ventilation function indexes,MVV、FEV_1、V_(50)/Ht and PEFR increased significantly (P<0.05, P<0.01). Among the EEG indexes,QTd value and QTcd value decreased significantly (P<0.05,P<0.01). Conclusion Aerobic exercises could improve the pulmonary ventilation function of simple obesity primary school students,and had favorable regulations on electrocardiac activity.
2.Carbonic anhydrase IX-based tumor imaging and therapy: a review.
Jia LIN ; Dianyu WANG ; Jianfeng LIU ; Lijun YANG ; Jinjian LIU
Chinese Journal of Biotechnology 2023;39(1):116-131
Carbonic anhydrase IX (CAIX) is a transmembrane protein that is specifically overexpressed on the surface of hypoxic tumor cells. With the function of regulating the acidity of tumor cells both inside and outside, CAIX is closely related to tumor proliferation, invasion and metastasis. Therefore, CAIX is a promising target for tumor imaging and therapy. Herein, we summarized recent advances in CAIX-based tumor imaging, therapy and theranostics, and prospected future applications of using CAIX as an anti-tumor target.
Carbonic Anhydrase IX
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Carbonic Anhydrases/metabolism*
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Cell Line, Tumor