1.Clinical study of open surgery for small and middle abdominal wall incision hernia
Yake CHEN ; Dianchen WANG ; Jianmin CHEN ; Yi ZHANG ; Pan QU ; Xinguang QIU
International Journal of Surgery 2021;48(1):15-19
Objective:To discuss the feasibility and value of open treatment for small and middle abdominal incision hernia repair.Methods:Retrospective analysis of 110 patients with abdominal wall incision hernia repair in our hospital from January 2016 to January 2018. They were divided into two groups according to the different operation, including open treatment group ( n=57)and laparoscopic treatment group ( n=53), the VAS efficacy scores, anal exhaust time, defecating time, removal of gastric tube time, removal of drainage tube time, first feed time, postoperative hospital stay time, hospitalization expenses were observed and analyzed respectively, measurement date with normal distribution were expressed as ( Mean± SD), comparisons between groups were analyzed using t test. Comparisons of count date between groups were analyzed using chi-square test. Results:All the patients were discharged, the VAS efficacy scores in open treatment about one day or three day and five day were (4.02±0.19), (2.21±0.26), (1.39±0.98) scores, the VAS efficacy scores in laparoscopic treatment were (4.68±0.62), (2.76±1.18), (1.84±0.62) scores, there were differences in complications between the two groups( P<0.05). The anal exhaust time, defecating time, removal of gastric tube time, removal of drainage tube time, first feed time of open treatment group were (50.73±14.69) h, (87.21±13.75) h, (9.64±3.92) h, (3.42±1.22) d, (37.11±9.76) h, and the laparoscopic treatment group were (65.14±9.54) h, (89.73±11.56) h, (11.43±5.61) h, (2.81±1.39) d, (38.92±7.59) h, there were differences complications between the two groups( P<0.05). The postoperative hospital stay time of open treatment group were (9.14±0.03) d, the postoperative hospital stay time of laparoscopic treatment group were (9.74±0.49) d, there were not differences in complications between the two groups( P<0.05). The hospitalization expenses in open treatment group were (1.51±0.36) ten thousand yuan, the hospitalization expenses in laparoscopic treatment group were(2.13±1.06) ten thousand yuan, there were differencesin complications between the two groups( P<0.05). Conclusion:Application of open treatment is feasible and effeetive for small and middle abdominal wall incision hernia.
2.Predictive value of triglyceride, glycosylated hemoglobin and their interactions on gestational diabetes mellitus
Zichao BAO ; Cheng TAO ; Dianchen CHEN
Shanghai Journal of Preventive Medicine 2025;37(4):361-367
ObjectiveTo investigate the diagnostic value of triglyceride (TG) and glycosylated hemoglobin (HbA1c) and their interactions on gestational diabetes mellitus (GDM), so as to provide a basis for future pregnancy monitoring and clinical decision-making. MethodsData of 100 full-term singleton pregnant women who were examined and delivered in the Second People’s Hospital of Wuhu City from January 2020 to January 2023 were retrospectively collected, and they were divided into GDM group (n=33) and non-GDM group (n=67) according to the results of oral glucose tolerance test (OGTT). The general clinical data of the two groups were compared, and the independent risk factors affecting the occurrence of GDM were analyzed using logistic regression analysis. Furthermore, the diagnostic value of the interaction of HbA1c and TG on GDM was analyzed using additive interaction model. A nomogram model to predict the occurrence of GDM was constructed and verified. The effects of HbA1c, TG and their interactions on the occurrence of GDM were analyzed using the receiver operating characteristic curve (ROC). ResultsHbA1c and TG were significantly higher in the GDM group than those in the non-GDM group (P<0.001). History of GDM, family history of diabetes mellitus, body mass index (BMI) before pregnancy, hypertension, TG, frequent consumption of high-calorie food during pregnancy, and HbA1c were the influencing factors for the occurrence of GDM in pregnant women (P<0.001). The nomogram model was constructed according to the seven factors screened by logistic regression analysis, and the average absolute error between the predicted probability by the nomogram model and actual probability of the occurrence of GDM was 0.039. The ROC results showed that the area under the curve (AUC) value of HbA1c was 0.765, the AUC value of TG was 0.833, and the AUC value of the interaction between TG and HbA1c was 0.894, with a statistically significant difference (P<0.05). ConclusionHbA1c and TG are not only influencing factors for GDM, but also their interactions are positively correlated with the occurrence of GDM. The diagnostic value of the two synergistically interacting on GDM is greater than that of them independently on GDM. The nomogram model constructed in this study has good differentiation, accuracy and clinical practicability for predicting the incidence of GDM.