Type 2 diabetes mellitus (DM) is becoming major health threat worldwide and it is extremely common in clinical setting. Malaysia is one of the highest diabetic populations among Asian countries and the new cases are increasing day to day. Early detection of people with high risk of Type 2 DM by using simple, easy and cost-effective assessment tool is the better way to identify and prevent the community from this non-communicable disease. The objectives of the study were to identify those are high risk to become type 2DM among Malaysians by using risk scoring form and to educate them how to prevent it. Total 591 subjects were recruited from the health screening programs carried out by the collaboration of Petaling Jaya Development Council (MBPJ) and Lincoln University College, Malaysia. Modified form of Finnish Type 2 Diabetes Risk Assessment Tool was used to identify people at risk of becoming type 2 DM. Descriptive analysis was performed for all included variables in this study by using SPSS version 21. The study found out that almost half of the participants were found to have family history of DM, 60% of them were overweight and obese and 47% were having above normal waist circumference. We observed that nearly 60 % of participants in the study were having moderate to high risk of becoming type 2 DM in next 10 years. To conclude, the result of our study would be helpful in implementation of cost-effective, convenient Type 2 DM risk assessment tool which has yet to be implemented in Malaysia.
Type 2 diabetes mellitus ; assessment tool ; health screening ; prevention

Adolescent ; Child ; Diabetes Mellitus, Type 1 ; prevention & control ; therapy ; Diabetes Mellitus, Type 2 ; prevention & control ; therapy ; Humans

Blood Glucose ; analysis ; Diabetes Complications ; prevention & control ; Diabetes Mellitus, Type 2 ; blood ; therapy ; Humans ; Risk Factors

BACKGROUNDAs the incidence of type 2 diabetes is rapidly increasing, prevention of the disease should be considered as a crucial objective in the near future. Several studies have shown angiotensin receptor blockers (ARBs) may contribute to the prevention of new-onset type 2 diabetes. This study was conducted to determine if ARBs as monotherapy or combination therapy may experience a decreased incidence of new-onset type 2 diabetes and prevent cardiovascular events.

METHODSRelevant experimental and clinical studies were identified by searching MEDLINE (1969 to May 30, 2011) to extract a consensus of trial data involving the effect of ARBs on prevention of new-onset type 2 diabetes and cardiovascular events. Studies were included if they were randomized controlled trials versus placebo/routine therapy. A random-effects model was utilized. Subgroup and sensitivity analyses were conducted.

RESULTSEleven trials were identified, including 82 738 patients. ARBs prevented new-onset type 2 diabetes (odds ratio 0.8 (95%CI 0.76, 0.85)). Regardless of indication for use, essential hypertension (seven trials), impaired glucose tolerance (one trial), cardiocerebrovascular disease (two trials) or heart failure (one trial), reductions in new-onset type 2 diabetes were maintained (0.75 (0.69, 0.82), 0.85 (0.78, 0.92), 0.80 (0.76, 0.85) and 0.80 (0.64, 0.99), respectively). No statistical heterogeneity was observed for any evaluation. However, ARBs did not significantly reduce the odds of all-cause mortality, myocardial infarction and heart failure versus control therapy among all of these studies. But ARBs did reduce the odds of cardiac death and heart failure among the heart failure study versus control therapy.

CONCLUSIONARBs have significant ability to reduce risk of developing new-onset type 2 diabetes but does not improve cardiovascular outcomes over the study follow-up periods among all of included studies.

Angiotensin Receptor Antagonists ; therapeutic use ; Cardiovascular Diseases ; prevention & control ; Diabetes Mellitus ; prevention & control ; Diabetes Mellitus, Type 2 ; prevention & control ; Humans ; Hypertension ; prevention & control ; Randomized Controlled Trials as Topic

Cardiovascular Diseases ; complications ; prevention & control ; Diabetes Mellitus, Type 2 ; complications ; prevention & control ; Humans ; Metabolic Syndrome ; complications ; prevention & control

Diabetic kidney disease (DKD) is one of the major chronic complications of diabetes and is associated with a heavy disease burden. Since the release of the National Guidelines for the Prevention and Control of Diabetes in Primary Care (2018), there has been continuous improvement in the basic public health services and basic medical services of the primary care setting and an expansion of the scope of work. Therefore, more detailed technical guidelines for the prevention and management of diabetes and its complications in primary care are needed. This guide aims to promote the standardization of DKD prevention and control in primary care, to assist primary care physicians with the prevention and control of DKD, and to ensure the comprehensive management of patients with DKD. The contents include the basic requirements for the management, overview, screening, diagnosis and staging, treatment, follow-up, and referral of patients with DKD.
Humans ; Diabetes Mellitus, Type 2/complications* ; Diabetic Nephropathies/prevention & control* ; Primary Health Care

"Let food be thy medicine and medicine be thy food"-the ancient adage proposed by Greek philosopher Hippocrates of Kos thousands of years ago already acknowledged the importance of the beneficial and health-promoting effects of food nutrients on the body (Mafra et al., 2021). Recent epidemiological and large-scale community studies have also reported that unhealthy diets or eating habits may contribute heavily to the burden of chronic, non-communicable diseases, such as obesity, type 2 diabetes mellitus (T2DM), hypertension, cardiovascular disease (CVD), cancer, neurodegenerative diseases, arthritis, chronic kidney disease (CKD), and chronic obstructive pulmonary disease (COPD) (Jayedi et al., 2020; Gao et al., 2022). Emerging evidence highlights that a diet rich in fruits and vegetables can prevent various chronic diseases (Chen et al., 2022). Food bioactive compounds including vitamins, phytochemicals, and dietary fibers are responsible for these nutraceutical benefits (Boeing et al., 2012). Recently, phytochemicals such as polyphenols, phytosterols, and carotenoids have gained increasing attention due to their potential health benefits to alleviate chronic diseases (van Breda and de Kok, 2018). Understanding the role of phytochemicals in health promotion and preventing chronic diseases can inform dietary recommendations and the development of functional foods. Therefore, it is crucial to investigate the health benefits of phytochemicals derived from commonly consumed foods for the prevention and management of chronic diseases.
Humans ; Diabetes Mellitus, Type 2 ; Diet ; Vegetables/chemistry* ; Cardiovascular Diseases/prevention & control* ; Phytochemicals ; Chronic Disease

OBJECTIVETo summarize the importance of Mediterranean diet in the prevention and management of type 2 diabetes.

DATA SOURCESWe searched electronic database on PubMed up to 14 April 2014, we identified these articles with following key words: "Mediterranean diet" and "diabetes". The initial search resulted in 451 entries. The search strategy had no language and publication date restrictions. The relevance of the studies was assessed based only on the title and abstract. The studies included in our review had to match the following inclusion criteria: (1) randomized clinical trials and meta-analysis or systematic review, and (2) provided strong evidence for the diet as a way to prevent type 2 diabetes, and improve glycemic control and cardiovascular risk factors in diabetic patients. We reviewed 49 manuscripts and only 22 met our inclusion criteria.

STUDY SELECTIONRelevant literatures including randomized control trials, meta-analysis or systematic review.

RESULTSBased on several studies, Mediterranean diet is inversely related to type 2 diabetes and plays important roles in the management of type 2 diabetes. Based on the evidence gathered and evaluated from various studies, we concluded combination and interaction of Mediterranean diet components, such as fruits, vegetables, nuts, legumes, whole grains, fish and moderate intakes of red wine, which contain essential nutrients and health promoting properties, including high fibers, high magnesium, high anti-oxidant and high monounsaturatal fatty acids (MUFA). Interaction and combination of these essential nutrients and health promoting properties found to lower body weight, hemoglobin A1C (HbA1c), low density lipoprotein (LDL), oxidative-stress and improve high density lipoprotein (HDL) level; which are beneficial for prevention and prognosis improvement of type 2 diabetes.

CONCLUSIONSIn the modern society, poor dietary habits accompanied by inadequate physical activity are associated with the risk of having obesity and type 2 diabetes. Promoting healthy lifestyle and diet are not only beneficial in the prevention and treatment of various diseases but also important in maintaining the overall health. Switching from unhealthy diet to health-friendly diet such as Mediterranean diet represents healthy lifestyle choice.

Antioxidants ; metabolism ; Diabetes Mellitus, Type 2 ; metabolism ; prevention & control ; Diet, Mediterranean ; Fatty Acids, Monounsaturated ; metabolism ; Humans ; Magnesium ; metabolism

OBJECTIVETo investigate the prevention and management of complications after laparoscopic gastric bypass (LRYGB) operation.

METHODSClinical data of 82 cases (9 cases of simple obesity, 55 of obesity complicated with type 2 diabetes, 18 of non-obesity simple type 2 diabetes) undergoing LRYGB in our hospital between May 2010 to May 2013 were retrospectively analyzed. Cause of complication was explored and experience was summarized in order to provide reference to clinical practice.

RESULTS RESULTSThere was no mortality and re-admission within 30 days after procedures. Nine patients developed complications. Punctural injury occurred in 1 patient(1.2%) and laparotomy surgery was performed to stop bleedind. Hemorrhage was observed in 4 patients(4.9%, one patients had concurrent anastomotic ulcer) and was cured by either gastrolavage with solution of epinephrine and normal saline or cautery under gastroscope. Anastomotic leakage occurred in one patient(1.2%) which was cured by placing nose-gastro tube immediately after diagnosis of leakage and total enteral nutrition for one month. Anastomotic stricture occurred in 1 patient(1.2%), general peritonitis occurred after balloon dilation and laparoscopic repair was performed to repair the perforation due to dilation. Gastroplegia occurred in two patients(2.4%) and was cured after fasting, gastrointestinal decompression, usage of gastrointestinal prokinetic medications and enteral nutrition. All complications were cured at last. BMI of all patients dropped in vary extent after a follow up of 19.0-35.0(29.1±5.4) months.

CONCLUSIONSComplication after LRYGB operation may be prevented by active preoperative preparation, surgical precision, and intensive postoperative care. Even complications occur, the corresponding treatments are effective.

Anastomotic Leak ; Diabetes Mellitus, Type 2 ; Gastric Bypass ; adverse effects ; Humans ; Laparoscopy ; Postoperative Complications ; prevention & control ; therapy ; Retrospective Studies

Bariatric Surgery ; adverse effects ; Diabetes Mellitus, Type 2 ; complications ; prevention & control ; Humans ; Obesity, Morbid ; complications ; surgery ; Treatment Outcome ; Weight Loss