A 13 year old boy was diagnosed as primary nephrotic diabetesinsipidus, whose symptom has been devloped from 3 years of age, subsequetly he developed bilateral hydronephrosis and neurogenic bladder. His pedigree could be explored 5 generations and represented inheritace as X-linked recesslive transmission, He was treated with indomethacin 2mg/Kg/day plus chlorothiazid 500mg/dau and this new method shows markedly decreased urine outpur and increased urine osmolarity.
Adolescent ; Diabetes Insipidus, Nephrogenic* ; Family Characteristics ; Humans ; Hydronephrosis ; Indomethacin ; Male ; Osmolar Concentration ; Pedigree ; Urinary Bladder, Neurogenic

No abstract available.
Diabetes Insipidus, Nephrogenic*

Tuberculous menigitis is relatively common disease and delay in treatment is associated with many neurologic sequelae. Of the neurologic disorder, diabets insipidus is extreamly rare. Diabetes insipidus is a syndrome characterized by the excretion of abnormally large volumes of dilute urine. It is divided into central diabets insipidus, nephrogenic diabetes insipidus, primary polydipsia and gestational daibetes insipidus. In this four type of diabetes insipidus, central diabetes insipidus is a polyuric disorder results from a lack of sufficient antidiuretic hormone to effect appropriate concentration of the urine for water conservration. We report a 25-year old male who had prolonged head ache and subsequently followed by polyuria. He was dia gonsed as the tuberculous meningitis by laboratory find ing and smear of CSF, and diagnosed central diabetes insipidus by serum osmolality & Na+ & AVP (arginine va sopressin), urine osmolality & specific gravity, adminis tration of vasopressin. He maintained the water balance of body by administration of vasopressin, but without im provement of mental status, sudden cardiac arrest occurs on 20th hospital day
Adult ; Death, Sudden, Cardiac ; Diabetes Insipidus* ; Diabetes Insipidus, Nephrogenic ; Diabetes Insipidus, Neurogenic ; Head ; Humans ; Male ; Nervous System Diseases ; Osmolar Concentration ; Polydipsia, Psychogenic ; Polyuria ; Specific Gravity ; Tuberculosis, Meningeal* ; Vasopressins ; Water

Brachycephaly is a kind of craniosynostosis. Because of premature closure of the coronal suture, the skull is shorter in the anteroposterior diameter but is widened with a high vault and the occiput and forehead are flattened. Diabetes insipidus had been reported in oxycephaly. We have experienced a case of central diabetes insipidus associated with brachycephaly. A brief review of related literatures is included in this report.
Craniosynostoses* ; Diabetes Insipidus ; Diabetes Insipidus, Neurogenic* ; Forehead ; Skull ; Sutures

No abstract available.
Diabetes Insipidus, Nephrogenic* ; Urinary Bladder*

No abstract available.
Diabetes Insipidus, Nephrogenic* ; Humans ; Siblings*

Diabetes insipidus is a disorder caused by complete or partial deficiency or unresponsiveness to antidiuretic hormone. Both diabetes mellitus and diabetes insipidus are well-known causes of polyuria and polydipsia. Although Wolfram Syndrome, which is characterized by the concurrence of diabetes mellitus and diabetes insipidus along with optic atrophy and ataxia, is frequently reported, the concurrence of diabetes insipidus and type 2 diabetes mellitus without optic atrophy and deafness is rare. We report a 31-year-old woman presenting with hyperglycemic hyperosmolar syndrome caused by type 2 diabetes mellitus complicated with concurrent central diabetes insipidus.
Adult ; Ataxia ; Deafness ; Diabetes Insipidus ; Diabetes Insipidus, Neurogenic ; Diabetes Mellitus ; Diabetes Mellitus, Type 2 ; Female ; Humans ; Hyperglycemia ; Optic Atrophy ; Polycystic Ovary Syndrome ; Polydipsia ; Polyuria ; Wolfram Syndrome

Diabetes insipidus is a disorder caused by complete or partial deficiency or unresponsiveness to antidiuretic hormone. Both diabetes mellitus and diabetes insipidus are well-known causes of polyuria and polydipsia. Although Wolfram Syndrome, which is characterized by the concurrence of diabetes mellitus and diabetes insipidus along with optic atrophy and ataxia, is frequently reported, the concurrence of diabetes insipidus and type 2 diabetes mellitus without optic atrophy and deafness is rare. We report a 31-year-old woman presenting with hyperglycemic hyperosmolar syndrome caused by type 2 diabetes mellitus complicated with concurrent central diabetes insipidus.
Adult ; Ataxia ; Deafness ; Diabetes Insipidus ; Diabetes Insipidus, Neurogenic ; Diabetes Mellitus ; Diabetes Mellitus, Type 2 ; Female ; Humans ; Hyperglycemia ; Optic Atrophy ; Polycystic Ovary Syndrome ; Polydipsia ; Polyuria ; Wolfram Syndrome

Polyuria is occasionally observed after general anesthesia with sevoflurane. Usually the onset of polyuria is abrupt and remission is spontaneous, so it's not so easy to do detailed investigation. The authors came across with two cases of polyuria during general anesthesia with sevoflurane which occurred so early around one hour after induction of anesthesia. Both cases revealed no special problem like central diabetes insipidus.
Anesthesia ; Anesthesia, General ; Diabetes Insipidus, Neurogenic ; Polyuria*

We describe a case of congenital nephrogenic diabetes insipidus with severe dilatation of bilateral urinary tracts without anatomical obstructions. Functional obstruction can be occurred when polyuria surpasses the transporting ability of urine in the urinary tract. The patient was admitted to our hospital due to decreased mentality developed after traffic accident. On radiologic study, bilateral hydronephrosis and hydroureter were noted. Because the patient excreted copious dilute urine, we performed water deprivation test and the result was consistent with nephrogenic diabetes insipidus. We are presenting this case in an attempt to describe strong association between congenital diabetes insipidus and nonobstructive hydronephrosis in which polyuria is responsible for the hydronephrosis.
Accidents, Traffic ; Diabetes Insipidus ; Diabetes Insipidus, Nephrogenic* ; Dilatation ; Humans ; Hydronephrosis* ; Polyuria ; Urinary Tract ; Water Deprivation