1.Congenital Nephrogenic Diabetes Insipidus with Bilateal Hydronephrosis: Indomethacin in Treatment of Nephrogenic Diabetes Insipidus.
Young Mo SOHN ; Chul LEE ; Pyung Kil KIM ; Duk Jin YUN
Yonsei Medical Journal 1980;21(2):116-122
A 13-year-old boy was diagnosed as having primary nephrogenic diabetes insipidus, and symptoms developed at 3 years of age. Subsequently he developed bilateral hydronephrosis and a neurogenic bladder. His pedigree could be explored back 5 generations and represented an inheritance as an X-linked recessive transmission factor. He was treated with indomethacin 2 mg/kg/day plus chlorothiazide 500 mg/day and this new treatment showed a markedly decreased urine output and increased urine osmolarity. (Nephrogenic diabetes insipidus, Hydronephrosis, Indomethacin)
Adolescent
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Bladder, Neurogenic/etiology
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Chlorothiazide/therapeutic use
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Diabetes Insipidus/complications
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Diabetes Insipidus/congenital*
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Diabetes Insipidus/drug therapy
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Diabetes Insipidus/genetics
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Drug Therapy, Combination
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Human
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Hydronephrosis/etiology*
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Indomethacin/therapeutic use*
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Male
2.Case report of a thermal burns patient with diabetes insipidus.
Papua New Guinea medical journal 2011;54(1-2):56-58
We report a rare case of diabetes insipidus following fire burn injury. Meticulous fluid balance and the use of carbamazepine resulted in her survival.
Burns/*complications
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Carbamazepine/therapeutic use
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Diabetes Insipidus, Neurogenic/drug therapy/*etiology
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Female
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Fires
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Fluid Therapy/methods
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Humans
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Self-Injurious Behavior
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Young Adult
3.Lymphocytic Hypophysitis with Diabetes Insipidus: Improvement by Methylprednisolone Pulse Therapy.
Young Suk JO ; Hyo Jin LEE ; So Young RHA ; Woo Jung HONG ; Chang June SONG ; Young Kun KIM ; Heung Kyu RO
The Korean Journal of Internal Medicine 2004;19(3):189-192
Lymphocytic hypophysitis is a rare inflammatory disorder in the pituitary gland. The lesion is usually confined to the adenohypophysis. Although the involvement of the posterior pituitary gland or the stalk is rare, such patients with diabetes insipidus have been reported. Surgery has been used to make the definitive diagnosis. Recent studies suggest, however, that the pathologic diagnosis may not be necessary always. We reported a case of Lymphocytic hypophysitis managed by methylprednisolone pulse therapy. A 50-year-old premenopausal woman with Lymphocytic hypophysitis and diabetes insipidus was treated with methylprednisolone pulse therapy. Her adenopituitary lesion disappeared and the diabetes insipidus resolved. The optimal management for patients with lymphocytic hypophysitis may be the high index of the suspicion prior to the extensive surgical resection. In addition, methylprednisolone pulse therapy may improve the clinical and MRI findings.
Anti-Inflammatory Agents/*administration & dosage
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Diabetes Insipidus/*drug therapy/etiology
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Female
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Humans
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Lymphocytosis/complications/*drug therapy
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Methylprednisolone/*administration & dosage
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Middle Aged
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Pituitary Diseases/complications/*drug therapy
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Pulse Therapy, Drug
4.Diabetes insipidus after traumata of two extremes in severity.
Junichi YOSHIDA ; Akiyo SHIROOZU ; Akinori ZAITSU ; Yasuhiro IMAZONO ; Tomoko KOHROGI ; Kazunori YOKOHATA ; Hideki KISHIKAWA
Yonsei Medical Journal 1990;31(1):71-73
Two patients with post-traumatic diabetes insipidus (DI) are reported. One had suffered a fatal injury and the other a mild contusion without amnesia before DI developed. These two instances exemplify the wide spectrum of post-traumatic DI and, hence, the importance of ruling out DI even afer a mild closed-head injury.
Adult
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Case Report
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Central Nervous System/*injuries
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Desmopressin/therapeutic use
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Diabetes Insipidus/drug therapy/*etiology/physiopathology
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Diuresis/drug effects
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Female
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Human
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Male
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Middle Age
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Vasopressins/therapeutic use
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Wounds and Injuries/*complications/mortality
5.A Case of Transient Central Diabetes Insipidus after Aorto-Coronary Bypass Operation.
Chung Hoon YU ; Jang Hee CHO ; Hee Yeon JUNG ; Jeong Hoon LIM ; Mi Kyung JIN ; Owen KWON ; Kyung Deuk HONG ; Ji Young CHOI ; Se Hee YOON ; Chan Duck KIM ; Yong Lim KIM ; Gun Jik KIM ; Sun Hee PARK
Journal of Korean Medical Science 2012;27(9):1109-1113
Diabetes insipidus (DI) is characterized by excessive urination and thirst. This disease results from inadequate output of antidiuretic hormone (ADH) from the pituitary gland or the absence of the normal response to ADH in the kidney. We present a case of transient central DI in a patient who underwent a cardiopulmonary bypass (CPB) for coronary artery bypass grafting (CABG). A 44-yr-old male underwent a CABG operation. An hour after the operation, the patient developed polyuria and was diagnosed with central DI. The patient responded to desmopressin and completely recovered five days after surgery. It is probable that transient cerebral ischemia resulted in the dysfunction of osmotic receptors in the hypothalamus or hypothalamus-pituitary axis during CPB. It is also possible that cardiac standstill altered the left atrial non-osmotic receptor function and suppressed ADH release. Therefore, we suggest that central DI is a possible cause of polyuria after CPB.
Adult
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Antidiuretic Agents/therapeutic use
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Coronary Artery Bypass/*adverse effects
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Coronary Vessels
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Deamino Arginine Vasopressin/therapeutic use
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Diabetes Insipidus, Neurogenic/*diagnosis/drug therapy/etiology
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Humans
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Hypothalamus/radionuclide imaging
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Magnetic Resonance Imaging
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Male
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Pituitary Gland/radionuclide imaging
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Polyuria/diagnosis/etiology
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Postoperative Complications/*diagnosis/drug therapy/etiology